Development of a simplified spinal cord ischemia model in mice

Journal of Neuroscience Methods

Volumn 189, Issue 2, 2010, Pages 246-251

  Wang, Zhengfeng ^a,b   Yang, Wei ^b   Britz, Gavin W ^b   Lombard, Frederick W ^b   Warner, David S ^b   Sheng, Huaxin ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Mouse model; Spinal cord ischemia; Thoracoabdominal aneurysm; Thoracotomy

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CLAMPING; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE MODEL; LASER DOPPLER FLOWMETRY; LUMBAR SPINE; MALE; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM FUNCTION; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RECTUM TEMPERATURE; ROTAROD TEST; SPINAL CORD BLOOD FLOW; SPINAL CORD ISCHEMIA; SPINAL CORD VENTRAL HORN; SURVIVAL RATE; THORACIC AORTA; THORACOTOMY; ANIMAL; BLOOD FLOW; C57BL MOUSE; CELL DEATH; LOCOMOTION; NERVE CELL; PATHOLOGY; PROCEDURES; RANDOMIZATION; SPINAL CORD; SURGICAL EQUIPMENT; TIME; VASCULARIZATION;

ANIMALS; AORTA, THORACIC; CELL DEATH; DISEASE MODELS, ANIMAL; LOCOMOTION; MALE; MICE; MICE, INBRED C57BL; NEURONS; RANDOM ALLOCATION; REGIONAL BLOOD FLOW; ROTAROD PERFORMANCE TEST; SPINAL CORD; SPINAL CORD ISCHEMIA; SURGICAL INSTRUMENTS; THORACOTOMY; TIME FACTORS;

EID: 77953135452     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.04.003     Document Type: Article

References (29)

1. Basso D.M., Beattie M.S., Bresnahan J.C. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 1996, 139:244-256.
2. Cambria R.P., Davison J.K., Carter C., Brewster D.C., Chang Y., Clark K.A., Atamian S. Epidural cooling for spinal cord protection during thoracoabdominal aneurysm repair: a five-year experience. J Vasc Surg 2000, 31:1093-1102.
3. Casey P.J., Black J.H., Szabo C., Frosch M., Albadawi H., Chen M., Cambria R.P., Watkins M.T. Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion. J Vasc Surg 2005, 41:99-107.
4. Coselli J.S., Lemaire S.A., Koksoy C., Schmittling Z.C., Curling P.E. Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial. J Vasc Surg 2002, 35:631-639.
5. Farooque M., Suo Z., Arnold P.M., Wulser M.J., Chou C.T., Vancura R.W., Fowler S., Festoff B.W. Gender-related differences in recovery of locomotor function after spinal cord injury in mice. Spinal Cord 2006, 44:182-187.
6. Gaviria M., Bonny J.M., Haton H., Jean B., Teigell M., Renou J.P., Privat A. Time course of acute phase in mouse spinal cord injury monitored by ex vivo quantitative MRI. Neurobiol Dis 2006, 22:694-701.
7. Gaviria M., Haton H., Sandillon F., Privat A. A mouse model of acute ischemic spinal cord injury. J Neurotrauma 2002, 19:205-221.
8. Guertin P.A. Semiquantitative assessment of hindlimb movement recovery without intervention in adult paraplegic mice. Spinal Cord 2005, 43:162-166.
9. Gulino R., Dimartino M., Casabona A., Lombardo S.A., Perciavalle V. Synaptic plasticity modulates the spontaneous recovery of locomotion after spinal cord hemisection. Neurosci Res 2007, 57:148-156.
10. Kanellopoulos G.K., Kato H., Wu Y., Dougenis D., Mackey M., Hsu C.Y., Kouchoukos N.T. Neuronal cell death in the ischemic spinal cord: the effect of methylprednisolone. Ann Thorac Surg 1997, 64:1279-1285. (discussion 86).
11. Lang-Lazdunski L., Matsushita K., Hirt L., Waeber C., Vonsattel J.P., Moskowitz M.A., Dietrich W.D. Spinal cord ischemia. Development of a model in the mouse. Stroke 2000, 31:208-213.
12. Lapointe N.P., Ung R.V., Bergeron M., Cote M., Guertin P.A. Strain-dependent recovery of spontaneous hindlimb movement in spinal cord transected mice (CD1, C57BL/6, BALB/c). Behav Neurosci 2006, 120:826-834.
13. Lee H.J., Jakovcevski I., Radonjic N., Hoelters L., Schachner M., Irintchev A. Better functional outcome of compression spinal cord injury in mice is associated with enhanced H-reflex responses. Exp Neurol 2009, 216:365-374.
14. Marsala M., Yaksh T.L. Transient spinal ischemia in the rat: characterization of behavioral and histopathological consequences as a function of the duration of aortic occlusion. J Cereb Blood Flow Metab 1994, 14:526-535.
15. Safi H.J., Miller C.C., Azizzadeh A., Iliopoulos D.C. Observations on delayed neurologic deficit after thoracoabdominal aortic aneurysm repair. J Vasc Surg 1997, 26:616-622.
16. Safi H.J., Miller C.C., Huynh T.T., Estrera A.L., Porat E.E., Winnerkvist A.N., Allen B.S., Hassoun H.T., Moore F.A. Distal aortic perfusion and cerebrospinal fluid drainage for thoracoabdominal and descending thoracic aortic repair: ten years of organ protection. Ann Surg 2003, 238:372-380. (discussion 80-1).
17. Schepens M.A., Heijmen R.H., Ranschaert W., Sonker U., Morshuis W.J. Thoracoabdominal aortic aneurysm repair: results of conventional open surgery. Eur J Vasc Endovasc Surg 2009, 37:640-645.
18. Stone D.H., Albadawi H., Conrad M.F., Entabi F., Stoner M.C., Casey P.J., Cambria R.P., Watkins M.T. PJ34, a poly-ADP-ribose polymerase inhibitor, modulates visceral mitochondrial activity and CD14 expression following thoracic aortic ischemia-reperfusion. Am J Surg 2009, 198:250-255.
19. Stone D.H., Brewster D.C., Kwolek C.J., Lamuraglia G.M., Conrad M.F., Chung T.K., Cambria R.P. Stent-graft versus open-surgical repair of the thoracic aorta: mid-term results. J Vasc Surg 2006, 44:1188-1197.
20. Stone D.H., Conrad M.F., Albadawi H., Entabi F., Stoner M.C., Cambria R.P., Watkins M.T. Effect of PJ34 on spinal cord tissue viability and gene expression in a murine model of thoracic aortic reperfusion injury. Vasc Endovasc Surg 2009, 43:444-451.
21. Svensson L.G., Crawford E.S., Hess K.R., Coselli J.S., Safi H.J. Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg 1993, 17:357-368. (discussion 68-70).
22. Taira Y., Marsala M. Effect of proximal arterial perfusion pressure on function, spinal cord blood flow, and histopathologic changes after increasing intervals of aortic occlusion in the rat. Stroke 1996, 27:1850-1858.
23. Tiesenhausen K., Amann W., Koch G., Hausegger K.A., Oberwalder P., Rigler B. Cerebrospinal fluid drainage to reverse paraplegia after endovascular thoracic aortic aneurysm repair. J Endovasc Ther 2000, 7:132-135.
24. Tschop J., Czerner S., Nuscheler M., Thiel M. Epidural cooling. Neuroprotective treatment of thoracoabdominal aortic aneurysms. Anaesthesist 2008, 57:988-997.
25. Ung R.V., Lapointe N.P., Tremblay C., Larouche A., Guertin P.A. Spontaneous recovery of hindlimb movement in completely spinal cord transected mice: a comparison of assessment methods and conditions. Spinal Cord 2007, 45:367-379.
26. Wellons J.C., Sheng H., Laskowitz D.T., Burkhard Mackensen G., Pearlstein R.D., Warner D.S. A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. Brain Res 2000, 868:14-21.
27. Weidner N., Ner A., Salimi N., Tuszynski M.H. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proc Natl Acad Sci USA 2001, 98:3513-3518.
28. Wolpaw J.R., Tennissen A.M. Activity-dependent spinal cord plasticity in health and disease. Annu Rev Neurosci 2001, 24:807-843.
29. Yamamoto N., Takano H., Kitagawa H., Kawaguchi Y., Tsuji H. Changes of evoked action potentials and histology of the spinal cord, and hind limb dysfunction in spinal cord ischemia of cats. J Spinal Disord 1994, 7:285-295.