Persistence of a wild type Escherichia coli and its multiple antibiotic-resistant (MAR) derivatives in the abattoir and on chilled pig carcasses

International Journal of Food Microbiology

Volumn 140, Issue 2-3, 2010, Pages 249-253

  Delsol, Anne A ^a   Halfhide, Deborah E ^a   Bagnall, Mary C ^b   Randall, Luke P ^b   Enne, Virve I ^a   Woodward, Martin J ^b   Roe, John M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

Abattoir; E. coli; Food chain; Multiple antibiotic resistance (MAR); Pigs

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; CYCLOHEXANE; MULTIDRUG RESISTANCE PROTEIN; NALIDIXIC ACID; TETRACYCLINE; ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL SHEDDING; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM MUTANT; CARCASS; COLD STRESS; CONTROLLED STUDY; ESCHERICHIA COLI; FOOD CHAIN; FOOD PROCESSING; GENOTYPE; INDUCED HYPOTHERMIA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; SLAUGHTERHOUSE; STRAIN DIFFERENCE; SWINE; WILD TYPE; ANIMAL; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; MEAT; MICROBIOLOGY; MULTIDRUG RESISTANCE; MUTATION;

ABATTOIRS; ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; MEAT; MUTATION; SWINE;

ESCHERICHIA COLI; SUIDAE; SUS;

EID: 77953131918     PISSN: 01681605     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijfoodmicro.2010.03.023     Document Type: Article

References (35)

1. Aarestrupp F.M., Oliver Duran C., Burch D.G. Antimicrobial resistance in swine production. Animal Health Research Reviews 2008, 9:135-148.
2. Aarestrupp F.M., Wegener H.C., Collignon P. Resistance in bacteria of the food chain: epidemiology and control strategies. Expert Review in Anti-infective Therapy 2008, 6:733-750.
3. Alekshun M.N., Levy S.B. Regulation of chromosomally meditated multiple antibiotic resistance: the mar regulon. Antimicrobial Agents and Chemotherapy 1997, 41:2067-2075.
4. Andrews J.M. Determination of minimum inhibitory concentrations. Journal of Antimicrobial Chemotherapy 2001, 48(Supplement 1):5-16.
5. Cohen S.P., Mc Murray L.M., Hooper D.C., Wolfson J.S., Levy S.B. Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to Ompf reduction. Antimicrobial Agents and Chemotherapy 1989, 33:1318-1325.
6. Delsol A.A., Anjum M., Woodward M.J., Sunderland J., Roe J.M. The effect of chlortetracycline treatment and its subsequent withdrawal on multi-resistant Salmonella enterica serovar Typhimurium DT104 and commensal E. coli in the pig. Journal of Applied Microbiology 2003, 95:1226-1234.
7. Delsol A.A., et al. Emergence of fluoroquinolone resistance in the native Campylobacter population of pigs exposed to enrofloxacin. Journal of Antimicrobial Chemotherapy 2004, 53:872-874.
8. Delsol A.A., Woodward M.J., Roe J.M. Effect of a 5-day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig. Journal of Antimicrobial Chemotherapy 2004, 53:396-398.
9. Enne V.I., et al. Assessment of the fitness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element. Journal of Antimicrobial Chemotherapy 2005, 56:544-551.
10. Enne V.I., Cassar C., K.S., Woodward M.J., Bennett P.M. A high prevalence of antimicrobial resistant Escherichia coli isolated from pigs and a low prevalence of antimicrobial resistant E. coli from cattle and sheep in Great Britain at slaughter. FEMS Microbiology Letters 2008, 278:193-199.
11. Fontaine F., Stewart E.J., Lindner A.B., Taddei F. Mutations in two global regulators lower individual mortality in Escherichia coli. Molecular Microbiology 2008, 67:2-14.
12. George A.M., Levy S.B. Amplifiable resistance to tetracycline, chloramphenicol, and other antibiotics in Escherichia coli: involvement of a non-plasmid-determined efflux of tetracycline. Journal of Bacteriology 1983, 155:531-540.
13. Gibb A.P., Lewin C.S., Garden O.J. Development of quinolone resistance and multiple antibiotic resistance in Salmonella bovismorbificans in a pancreatic abscess. Journal of Antimicrobial Agents and Chemotherapy 1991, 28:318-321.
14. Gold H.S., Moellering R.C. Antimicrobial drug resistance. New England Journal of Medicine 1996, 335:1445-1453.
15. Hammerum A.M., Heuer O.E. Human health hazards from antimicrobial-resistant Escherichia coli of animal origin. Clinical Infectious Diseases 2009, 48:916-921.
16. Harwood J.L. Temperature stress: reacting and adapting: lessons from poikilotherms. Annals of the New York Academy of Sciences 2007, 1113:52-57.
17. Howard A.J., et al. The emergence of ciprofloxacin resistance in Salmonella typhimurium. Journal of Antimicrobial Chemotherapy 1990, 26:296-298.
18. Jacoby G.A., Archer G.L. New mechanisms of bacterial resistance to antimicrobial agents. New England Journal of Medicine 1991, 324:601-612.
19. Levy S.B. Antibiotic and antiseptic resistance: impact on public health. The Pediatric Infectious Disease Journal 2000, 19:S120-S122.
20. Lomovskaya O., Bostian K.A. Practical applications and feasibility of efflux pump inhibitors in the clinic-a vision for applied use. Biochemical pharmacology 2006, 71:910-918.
21. Mc Murray L.M., Oethinger M., Levy S.B. Overexpression of marA, soxS or AcrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli. FEMS Microbiology Letters 1998, 166:305-309.
22. Miller P.F., Gambino L.F., Sulavik M.C., Gracheck S.J. Genetic relationship between soxRS and mar loci promoting multiple antibiotic resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy 1994, 38:1773-1779.
23. Moken M.C., Mc Murray L.M., Levy S.B. Selection of multiple antibiotic resistant (mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci. Antimicrobial Agents and Chemotherapy 1997, 41:2270-2272.
24. Nowrouzian F., et al. Escherichia coli in infants' intestinal microflora: colonization rate, strain turnover, and virulence gene carriage. Pediatric Research 2003, 54:8-14.
25. Oethinger M., Podglajen I., Kern W.V., Levy S.B. Overexpression of the marA or soxS regulatory gene in clinical topoisomerase mutants of Escherichia coli. Antimicrobial Agents and Chemotherapy 1998, 42:2089-2094.
26. Okusu H., Nikaido H. AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants. Journal of Bacteriology 1996, 178:306-308.
27. Pers C., Sogaard P., Pallesen L. Selection of multiple resistance in Salmonella enteritidis during treatment with ciprofloxacin. Scandinavian Journal of Infectious Diseases 1996, 28:529-531.
28. Piddock L.J.V., White D.G., Gensberg K., Pumbwe L., Griggs D.J. Evidence for an efflux pump mediating multiple antibiotic resistance in Salmonella enterica serovar Typhimurium. Antimicrobial Agents and Chemotherapy 2000, 44:3118-3121.
29. Randall L.P., Woodward M.J. Multiple antibiotic resistance (mar) locus in Salmonella enterica serovar Typhimurium DT104. Applied and Environmental Microbiology 2001, 67:1190-1197.
30. Randall L.P., Cooles S.W., Sayer A.R., Woodward M.J. Cyclohexane resistance in Salmonella of different serovars is associated with increased resistance to multiple antibiotics, disinfectants and dyes. Journal of Medical Microbiology 2001, 50:1-6.
31. Randall L.P., et al. Farm disinfectants select for cyclohexane resistance, a marker of multiple antibiotic resistance, in Escherichia coli. Journal of Applied Microbiology 2005, 98:556-563.
32. Russell A.D. Do biocides select for antibiotic resistance?. Journal of Pharmacy and Pharmacology 2000, 52:227-233.
33. Russell A.D. Introduction of biocides into clinical practice and the impact on antibiotic resistant bacteria. Journal of Applied Microbiology 2002, 92:S121-S135.
34. Webber M., Piddock L.J.V. Absence of mutations in marRAB or soxRS in acrB-overexpressing fluoroquinolone resistant clinical and veterinary isolates of Escherichia coli. Antimicrobial Agents and Chemotherapy 2001, 45:1550-1552.
35. White D.G., Goldman J.D., Demple B., Levy S.B. Role of the AcrB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli. Journal of Bacteriology 1997, 179:6122-6126.