Do biocides select for antibiotic resistance?

Journal of Pharmacy and Pharmacology

Volumn 52, Issue 2, 2000, Pages 227-233

  Russell, A D ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM DERIVATIVE; ANTIBIOTIC AGENT; CHLORHEXIDINE; TRICLOSAN;

ANTIBIOTIC RESISTANCE; CONFERENCE PAPER; ESCHERICHIA COLI; METABOLIC ACTIVATION; NONHUMAN; STAPHYLOCOCCUS;

EID: 0034006523     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357001773742     Document Type: Conference Paper

References (69)

1. Alqurashi, A., Day, M. J., Russell, A. D. (1996) Susceptibility of some strains of enterococci and streptococci to antibiotics and biocides. J. Antimicrob. Chemother. 38: 745
2. Anderson, R. L., Carr, J. H., Bond, W. W., Favero, M. S. (1997) Susceptibility of vancomycin-resistant enterococci to environmental disinfectants. Infect. Cont. Hosp. Epidemiol. 18: 195-199
3. Bacquero, F., Patron, C., Canton, R., Ferrer, M. M. (1991) Laboratory and in-vitro testing of skin antiseptics: a prediction for in vitro activity. J. Hosp. Infect. 18 (Suppl. B): 5-11
4. Behr, H., Reverdy, M. E., Rabilat, C., Freney, J., Fleurette, J. (1994) Relation entre le niveau des concentrations mini-males inhibitrices de cinq antiseptiques et la prèsence du gène qacA chez Staphylococcus aureus. Pathol. Biol. 42: 438-444
5. Brown, M. L., Aldrich, H. C., Gauthier, J. J. (1995) Relationships between glycocalyx and povidone-iodine resistance in Pseudomonas aeruginosa (ATCC 27853) biofilms. Appl. Environ. Microbiol. 61: 187-193
6. Brown, M. R. W., Gilbert, P. (1993) Sensitivity of biofilms to antimicrobial agents. J. Appl. Bacteriol. Symp. Suppl. 74: 87S-97S
7. Chapman, J. S. (1998) Characterizing bacterial resistance to preservatives and disinfectants. Int. Biodet. Biodeg. 41: 241-245
8. Chapman, J. S., Diehl, M. A., Fearnside, K. B. (1998) Preservative tolerance and resistance. Int. J. Cosmet. Sci. 20: 31-39
9. Chopra, I. (1992) Efflux-based antibiotic resistance mechanisms: the evidence for increasing prevalence. J. Antimicrob. Chemother. 30: 737-739
10. Cohen, S. P., McMurry, L. M., Hooper, D. C., Wolfson, J. S., Levy, S. B. (1989) Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction. Antimicrob. Ag. Chemother. 33: 1318-1325
11. Cookson, B. D., Bolton, M. C., Platt, J. H. (1991a) Chlorhexidine resistance in methicillin resistant Staphylococcus aureus or just an elevated MIC? An in vitro and in vivo assessment. Antimicrob. Ag. Chemother. 35: 1997-2002
12. Cookson, B. D., Farrelly, H., Stapleton, P., Garvey, R. P. J., Price, M. R. (1991b) Transferable resistance to triclosan in MRSA. Lancet 1: 1548-1549
13. Costerton, J. W., Cheng, K.-J., Geesey, G. G., Ladd, T. I., Nickel, J. C., Dasgupta, M., Marrie, T. J. (1987) Bacterial biofilms in nature and disease. Ann. Rev. Microbiol. 41: 435-464
14. Courvalin, P. (1996) Evasion of antibiotic action by bacteria. J. Antimicrob. Chemother. 37: 855-869
15. Day, M. J., Russell, A. D. (1999) Bacterial sensitivity and resistance. F. Antibiotic-resistant cocci. In: Russell, A. D., Hugo, W. B., Ayliffe, G. A. J. (eds) Principles and Practice of Disinfection, Preservation and Sterilization. 3rd edn. Blackwell Science, Oxford, pp 344-359
16. Fitzgerald, K. A., Davies, A., Russell, A. D. (1992) Sensitivity and resistance of Escherichia coli and Staphylococcus aureus to chlorhexidine. Lett. Appl. Microbiol. 14: 33-36
17. Gandhi, P. A., Sawant, A. D., Wilson, L. A., Ahearn, D. G. (1993) Adaptation and growth of Serratia marcescens in contact lens disinfectant solutions containing chlorhexidine gluconate. Appl. Environ. Microbiol. 59: 183-188
18. George, A. M. (1996) Multidrug resistance in enteric and other Gram-negative bacteria. FEMS Microbiol. Lett. 139: 1-10
19. Haines, K. A., Klein, D. A., McDonnell, G., Pretzer, D. (1997) Could antibiotic-resistant pathogens be cross-resistant to hard-surface disinfectants? Am. J. Infect. Control 25: 439-441
20. Handwerger, S., Tomasz, A. (1985) Antibiotic tolerance among clinical isolates of bacteria. Rev. Infect. Dis. 7: 368-386
21. Heath, R. J., Yu, Y.-T., Shapiro, M. A., Olson, E., Rock, C. O. (1998) Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis. J. Biol. Chem. 273: 30316-30320
22. Heath, R. J., Rubin, J. R., Holland, D. R., Zhang, E., Snow, M. E., Rock, C. O. (1999) Mechanism of triclosan inhibition of bacterial fatty acid synthesis. J. Biol. Chem. 274: 11110-11114
23. Heir, E., Sundheim, G., Hoick, A. L. (1995) Resistance to quaternary ammonium compounds in Staphylococcus spp. isolated from the food industry and nucleotide sequence of the resistance plasmid pST827. J. Appl. Bacteriol. 79: 149-156
24. Heir, E., Sundheim, G., Holck, A. L. (1999) The qacG gene on plasmid pST94 confers resistance to quaternary ammonium compounds in staphylococci isolated from the food industry. J. Appl. Microbiol. 86: 378-388
25. Kummerle, N., Feucht, H. H., Kaulfers, P. M. (1996) Plasmid-mediated formaldehyde resistance in Escherichia coli: characterization of the resistance gene. Antimicrob. Ag. Chemother. 40: 2276-2279
26. Leelaporn, A., Paulsen, I. T., Tennent, J. M., Littlejohn, T. G., Skurray, R. A. (1994) Multidrug resistance to antiseptics and disinfectants in coagulase-negative staphylococci. J. Med. Microbiol. 40: 214-220
27. Levy, C. W., Roujeinikova, A., Sedelnikova, S., Baker, P. J., Stuitjet, A. R., Slabast, A. R., Rice, D. W., Rafferty, J. B. (1999) Molecular basis of triclosan activity. Nature 398: 384-385
28. Levy, S. B. (1992) Active efflux mechanisms for antimicrobial resistance. Antimicrob. Ag. Chemother. 36: 695-703
29. Lyon, B. R., Skurray, R. A. (1987) Antimicrobial resistance of Staphylococcus aureus: genetic basis. .Microbiol. Rev. 51: 88-134
30. McDonnell, G., Pretzer, D. (1998) Action and targets of triclosan. ASM News 64: 670-671
31. McDonnell, G., Russell, A. D. (1999) Antiseptics and disinfectants: activity, action and resistance. Clin. Microbiol. Rev. 12: 147-179
32. McMurry, L. M., Oethinger, M., Levy, S. B. (1998a) Triclosan targets lipid synthesis. Nature 394: 531-532
33. McMurry, L. M., Oethinger, M., Levy, S. B. (1998b) Overexpression of marA, soxS or acrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli. FEMS Microbiol. Lett. 166: 305-309
34. McMurry, L. M., McDermott, P. F., Levy, S. B. (1999) Genetic evidence that InhA of Mycobacterium smegmatis is a target for triclosan. Antimicrob. Ag. Chemother. 43: 711-713
35. Miller, P. F., Sulavik, M. C. (1996) Overlaps and parallels in the regulation of intrinsic multiple-antibiotic resistance in Escherichia coli. Mol. Microbiol. 21: 441-448
36. Moken, M. C., McMurry, L. M., Levy, S. B. (1997) Selection of multiple-antibiotic-resistant (Mar) mutants of Escherichia coli by using the disinfectant pine oil: roles of the mar and acrAB loci. Antimicrob. Ag. Chemother. 41: 2770-2772
37. Nicoletti, G., Boghossian, V., Gurevitch, F., Borland, R., Morgenroth, P. (1993) The antimicrobial activity in vitro of chlorhexidine, a mixture of isothiazolinomes ('Kathon' CG) and cetyltrimethylammonium bromide (CTAB). J. Hosp. Infect. 23: 87-111
38. Nies, D. H., Silver, S. (1995) Ion efflux systems involved in bacterial metal resistances. J Indust. Microbiol. 14: 186-199
39. Nikaido, H. (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264: 382-388
40. Ogase, H., Nagai, I., Kameda, K., Kume, S., Ono, S. (1992) Identification and quantitative analysis of degradation products of chlorhexidine with chlorhexidine-resistant bacteria with three-dimensional high performance liquid chromatography. J. Appl. Bacteriol. 73: 71-78
41. Paulsen, I. T., Brown, M. H., Skurray, R. A. (1996) Proton-dependent multidrug efflux systems. Microhiol. Rev. 60: 575-608
42. Paulsen, I. T., Brown, M. H., Skurray, R. A. (1998) Characterization of the earliest known Staphylococcus aureus plasmid encoding a multidrug efflux system. J. Bactcriol. 180: 3477-3479
43. Prince, H. N., Nonemaker, W. S., Norgard, R. C., Prince, D. L. (1978) Drug resistance with topical antiseptics. J. Pharm. Sci. 67: 1627-1631
44. Rouche, D. A., Cram, D. S., DiBeradino, D., Littlejohn, T. G., Skurray, R. A. (1990) Efflux-mediated antiseptic gene qacA from Staphylococcus aureus: common ancestry with tetracycline- and sugar-transport proteins. Mol. Microbiol. 4: 2051-2062
45. Roussow, F. T., Rowbury, R. J. (1984) Effects of the resistance plasmid R124 on the level of the OmpF outer membrane protein and on the response of Escherichia coli to environmental agents. J. Appl. Microbiol. 56: 73-79
46. Russell, A. D. (1997) Plasmids and bacterial resistance to biocides. J. Appl. Microbiol. 82: 155-165
47. Russell, A. D. (1998) Mechanisms of bacterial resistance to antibiotics and biocides. Progr. Med. Chem. 35: 133-197
48. Russell, A. D. (1999a) Bacterial resistance to disinfectants: present knowledge and future problems. J. Hosp. Infect. (Suppl.) In press.
49. Russell, A. D. (1999b) Bacterial sensitivity and resistance. B. Plasmids and bacterial resistance. In: Russell, A. D., Hugo, W. B., Ayliffe, G. A. J. (eds) Principles and Practice of Disinfection, Preservation and Sterilization. 3rd edn. Blackwell Science, Oxford, pp. 297-302
50. Russell, A. D., Chopra, I. (1996) Understanding Antibacterial Action and Resistance. Ellis Horwood, Chichester
51. Russell, A. D., Russell, N. J. (1995) Biocides: activity, action and resistance. In: Hunter, P. A., Darby, G. K., Russell, N. J. (eds) Fifty Years of Antimicrobials: Past Perspectives and Future Trends. 53rd Symposium of the Society for General Microbiology. Cambridge University Press, Cambridge, pp. 327-365
52. Russell, A. D., Furr, J. R., Maillaird, J.-Y. (1997) Microbial susceptibility and resistance to biocides. ASM News 63: 481-487
53. Russell, A. D., Hammond, S. A., Morgan, J. R. (1986) Bacterial resistance to antiseptics and disinfectants. J. Hosp. Infect. 7: 213-225
54. Russell, A. D., Hugo, W. B., Ayliffe, G. A. J. (1999) Eds, Principles and Practice of Disinfection, Preservation and Sterilization. 3rd edn. Blackwell Science, Oxford
55. Russell, A. D., Suller, M. T. E., Maillard, J.-Y., Furr, J. R. (1999) Do antiseptics and disinfectants select for antibiotic resistance? J. Med. Microhiol. 48: 613-615
56. Russell, A. D., Tattawasart, U., Maillard, J.-Y., Furr, J. R. (1998) Possible link between bacterial resistance and use of antibiotics and biocides. Antimicrob. Ag. Chemother. 42: 2151
57. Rutala, W. A. (1996) APIC guideline for selection and use of disinfectants. Amer. J. Infect. Cont. 24: 313-342
58. Rutala, W. A., Stiegel, M. M., Sarabi, F. A., Weber, D. J. (1997) Susceptibility of antibiotic-susceptible and antibiotic-resistant hospital bacteria to disinfectants. Infect. Control Hosp. Epidemiol. 18: 417-421
59. Schweizer, H. P. (1998) Intrinsic resistance to inhibitors of fatty acid biosynthesis in Pseudomonas aeniginosa is due to efflux: application of a novel technique for generation of unmarked Chromosomal mutations for the study of efflux systems. Antimicrob. Ag. Chemother. 42: 394-398
60. Silver, S., Nucifora, G., Chu, L., Misra, T. K. (1989) Bacterial ATPases: primary pumps for exporting toxic cations and anions. Trends Biochem. Sci. 14: 76-80
61. Stewart, M. J., Parikh, S., Xiao, G., Tonge, P. J., Kisker, C. (1999) Structural basis mechanism of enoyl reductase inhibition by triclosan. J. Mol. Biol. 290: 859-865
62. Stickler, D. J., King, J. B. (1999) Bacterial sensitivity and resistance. A. Intrinsic resistance. In Russell, A. D., Hugo, W. B., Ayliffe, G. A. J. (eds) Principles and Practice of Disinfection, Preservation and Sterilization, 3rd edn. Blackwell Science, Oxford
63. Stickler, D. J., Thomas, B., Clayton, J. C., Chawla, J. A. (1983) Studies on the genetic basis of chlorhexidine resistance. Br. J. Clin. Pract. Symp. Suppl. No. 25: 23-28
64. Suller, M. T. E., Russell, A. D. (1999) Antibiotic and biocide resistance in methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. J. Hosp. Inf. In press.
65. Sundheim, G., Langsgrud, S., Heir, E., Holck, A. L. (1998) Bacterial resistance to disinfectants containing quaternary ammonium compounds. Int. Biodet. Biodeg. 41: 235-239
66. Tattawasart, U., Maillard, J.-Y., Furr, J. R., Russell, A. D. (1999) Development of resistance to chlorhexidine diacetate and cetylpyridinium chloride in Pseudomonas stutzeri and changes in antibiotic susceptibility. J. Hosp. Infect. 42: 219-229
67. Thornsberry, C. (1991) Antimicrobial susceptibility testing: general considerations.In: Balows, A., Hausler, W. J., Herrmann, K. L., Isenberg, H. D., Shadomy, H. J. (eds) Manual of Clinical Microbiology 5th edn. American Society for Microbiology, Washington D.C. pp 1059-1064
68. Townsend, D. E., Ashdown, D., Greed, L. C., Grubb, W. B. (1984) Transposition of gentamicin resistance to staphylococcal plasmids encoding resistance to cationic agents. J. Antimicrob. Chemother. 14: 115-124
69. Westland, E. J., Stewart, P. S. (1996) Chlorine penetration into artificial biofilm is limited by a reaction-diffusion interaction. Environ. Sci. Technol. 30: 2078-2083