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Volumn 17, Issue 6, 2010, Pages 717-721

L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinson's disease

Author keywords

Cerebrospinal fluid; Free homocysteine; L Dopa; Oxidative stress; Parkinson's disease; Total homocysteine

Indexed keywords

HOMOCYSTEINE; LEVODOPA; METHIONINE;

EID: 77953130994     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2009.09.034     Document Type: Article
Times cited : (25)

References (25)
  • 1
    • 41149136558 scopus 로고    scopus 로고
    • Environmental exposures and gene regulation in disease etiology
    • Edwards T.M., and Myers J.P. Environmental exposures and gene regulation in disease etiology. Cien Saude Colet 13 (2008) 269-281
    • (2008) Cien Saude Colet , vol.13 , pp. 269-281
    • Edwards, T.M.1    Myers, J.P.2
  • 2
    • 0027319970 scopus 로고
    • Homocysteine, a thrombogenic agent, suppresses anticoagulant heparin sulfate expression in cultured porcine aortic endothelial cells
    • Nishinaga M., Ozawa T., and Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparin sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest 92 (1993) 1381-1386
    • (1993) J Clin Invest , vol.92 , pp. 1381-1386
    • Nishinaga, M.1    Ozawa, T.2    Shimada, K.3
  • 3
    • 0022552919 scopus 로고
    • Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
    • Starkebaum G., and Harian J.M. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 77 (1986) 1370-1376
    • (1986) J Clin Invest , vol.77 , pp. 1370-1376
    • Starkebaum, G.1    Harian, J.M.2
  • 4
    • 0029257541 scopus 로고
    • Homocysteine species as components of plasma redox thiol status
    • Ueland P.M. Homocysteine species as components of plasma redox thiol status. Clin Chem 41 (1995) 340-342
    • (1995) Clin Chem , vol.41 , pp. 340-342
    • Ueland, P.M.1
  • 5
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch G.N., and Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 338 (1998) 1042-1050
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 6
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: a common mutation in methylentetrahydrofolate reductase
    • Frosst P., Blom H.J., Milos R., et al. A candidate genetic risk factor for vascular disease: a common mutation in methylentetrahydrofolate reductase. Nat Genet 10 (1995) 111-113
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 7
    • 0031003514 scopus 로고    scopus 로고
    • Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
    • Joosten E., Lesaffre E., Riezler R., et al. Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?. J Gerontol 252 (1997) 76-79
    • (1997) J Gerontol , vol.252 , pp. 76-79
    • Joosten, E.1    Lesaffre, E.2    Riezler, R.3
  • 8
    • 0028788020 scopus 로고
    • Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study
    • Nygard O., Vollset S.E., Refsum H., et al. Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. JAMA 274 (1995) 1526-1533
    • (1995) JAMA , vol.274 , pp. 1526-1533
    • Nygard, O.1    Vollset, S.E.2    Refsum, H.3
  • 9
    • 0032889343 scopus 로고    scopus 로고
    • Identification of cognitive impairment in the elderly: homocysteine is an early marker
    • Lehmann M., Gottfries C.G., and Regland B. Identification of cognitive impairment in the elderly: homocysteine is an early marker. Dement Geriatr Cogn Disord 10 (1999) 12-20
    • (1999) Dement Geriatr Cogn Disord , vol.10 , pp. 12-20
    • Lehmann, M.1    Gottfries, C.G.2    Regland, B.3
  • 10
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman I.I., Kumaravel T.S., Lohani A., et al. Folic acid deficiency and homocysteine impair DNA in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 22 (2002) 1752-1762
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3
  • 11
    • 33646021307 scopus 로고    scopus 로고
    • Cabergoline scavenges peroxynitrite enhanced by L-DOPA therapy in patients with Parkinson's disease
    • Isobe C., Abe T., Kikuchi T., et al. Cabergoline scavenges peroxynitrite enhanced by L-DOPA therapy in patients with Parkinson's disease. Eur J Neurol 13 (2006) 346-350
    • (2006) Eur J Neurol , vol.13 , pp. 346-350
    • Isobe, C.1    Abe, T.2    Kikuchi, T.3
  • 12
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
    • Hughes A.J., Daniel S.E., Kifford L., et al. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55 (1992) 181-184
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kifford, L.3
  • 13
    • 0028804182 scopus 로고
    • Sulphate and cysteine levels in the plasma of patients with Parkinson's disease
    • Allain P., Bouil A.L., Cordillet E., et al. Sulphate and cysteine levels in the plasma of patients with Parkinson's disease. Neurotoxicol 16 (1995) 527-530
    • (1995) Neurotoxicol , vol.16 , pp. 527-530
    • Allain, P.1    Bouil, A.L.2    Cordillet, E.3
  • 14
    • 0031730543 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia in Parkinson's disease
    • Kuhn W., Roebroek R., Blom H., et al. Hyperhomocysteinaemia in Parkinson's disease. J Neurol 32 (1998) 811-812
    • (1998) J Neurol , vol.32 , pp. 811-812
    • Kuhn, W.1    Roebroek, R.2    Blom, H.3
  • 15
    • 17144464115 scopus 로고    scopus 로고
    • Nigral endothelial dysfunction, homocysteine, and Parkinson's disease
    • Müller T., Werne B., Fowler B., et al. Nigral endothelial dysfunction, homocysteine, and Parkinson's disease. Lancet 354 (1999) 126-127
    • (1999) Lancet , vol.354 , pp. 126-127
    • Müller, T.1    Werne, B.2    Fowler, B.3
  • 16
    • 33750320296 scopus 로고    scopus 로고
    • Iron metabolism in Parkinsonian syndromes
    • Berg D., and Hochstrasser H. Iron metabolism in Parkinsonian syndromes. Mov Disord 21 (2006) 1299-1310
    • (2006) Mov Disord , vol.21 , pp. 1299-1310
    • Berg, D.1    Hochstrasser, H.2
  • 17
    • 58649087623 scopus 로고    scopus 로고
    • Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice
    • Kundu S., Kumar M., Sen U., et al. Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice. J Cell Biochem 106 (2009) 119-126
    • (2009) J Cell Biochem , vol.106 , pp. 119-126
    • Kundu, S.1    Kumar, M.2    Sen, U.3
  • 18
    • 0036270262 scopus 로고    scopus 로고
    • Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease
    • Wenzhem D., Bruce L., Cutler R.G., et al. Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem 80 (2002) 101-110
    • (2002) J Neurochem , vol.80 , pp. 101-110
    • Wenzhem, D.1    Bruce, L.2    Cutler, R.G.3
  • 19
    • 0033845547 scopus 로고    scopus 로고
    • Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD
    • Yasui K, Kowa H, Nakaso K, et al. Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD. Neurology 2000;55:437-40.
    • (2000) Neurology , vol.55 , pp. 437-440
    • Yasui, K.1    Kowa, H.2    Nakaso, K.3
  • 20
    • 0030200681 scopus 로고    scopus 로고
    • Standardized methods to bioassay neurotrophic factors for dopaminergic neurons
    • Takeshima T., Shimoda K., Johnston J.M., et al. Standardized methods to bioassay neurotrophic factors for dopaminergic neurons. J Neurosci Methods 67 (1996) 27-41
    • (1996) J Neurosci Methods , vol.67 , pp. 27-41
    • Takeshima, T.1    Shimoda, K.2    Johnston, J.M.3
  • 21
    • 23044432096 scopus 로고    scopus 로고
    • Increased of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease
    • Isobe C., Murata T., Sato C., et al. Increased of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease. Life Sci 77 (2005) 1836-1843
    • (2005) Life Sci , vol.77 , pp. 1836-1843
    • Isobe, C.1    Murata, T.2    Sato, C.3
  • 22
    • 0034853461 scopus 로고    scopus 로고
    • L-dopa upregulates the expression and activities of methionine adenosyl-transferase and catechol-O-methyltransferase
    • Zhao W.Q., Latinwo L., Liu X.X., et al. L-dopa upregulates the expression and activities of methionine adenosyl-transferase and catechol-O-methyltransferase. Exp Neurol 171 (2001) 127-138
    • (2001) Exp Neurol , vol.171 , pp. 127-138
    • Zhao, W.Q.1    Latinwo, L.2    Liu, X.X.3
  • 23
    • 0030770405 scopus 로고    scopus 로고
    • Role of homocysteine in age-related vascular and non-vascular disease
    • Parnetti L., Bottigliert T., Lowenthal D., et al. Role of homocysteine in age-related vascular and non-vascular disease. Aging (Milano) 9 (1997) 241-257
    • (1997) Aging (Milano) , vol.9 , pp. 241-257
    • Parnetti, L.1    Bottigliert, T.2    Lowenthal, D.3
  • 24
    • 0028246870 scopus 로고
    • Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
    • Rantan R.R., Murphy T.H., and Baraban J.M. Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14 (1994) 4385-4392
    • (1994) J Neurosci , vol.14 , pp. 4385-4392
    • Rantan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 25
    • 0033586471 scopus 로고    scopus 로고
    • Blood vessels change in the mesencephalon of patients with Parkinson's disease
    • Faucheux B.A., Bonner A.M., Agid Y., et al. Blood vessels change in the mesencephalon of patients with Parkinson's disease. Lancet 353 (1999) 981-982
    • (1999) Lancet , vol.353 , pp. 981-982
    • Faucheux, B.A.1    Bonner, A.M.2    Agid, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.