Mechanism of collagen-induced release of 5-HT, PDGF-AB and sCD40L from human platelets: Role of HSP27 phosphorylation via p44/p42 MAPK

Thrombosis Research

Volumn 126, Issue 1, 2010, Pages 39-43

  Kato, Hisaaki ^a   Adachi, Seiji ^a   Doi, Tomoaki ^a   Matsushima Nishiwaki, Rie ^a   Minamitani, Chiho ^a,b   Akamatsu, Shigeru ^c   Enomoto, Yukiko ^a   Tokuda, Haruhiko ^a,d   Otsuka, Takanobu ^b   Iwama, Toru ^a   Kozawa, Osamu ^a   Ogura, Shinji ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c Matsunami General Hospital   (Japan)

^d NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

5 HT; collagen; HSP27; PDGF AB; platelet; release; sCD40L

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CD40 LIGAND; COLLAGEN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR AB; PROTEIN P42; PROTEIN P44; SEROTONIN; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; FLAVONOID; HSPB1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR AB;

ARTICLE; BLOOD DONOR; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SEROTONIN BLOOD LEVEL; SEROTONIN RELEASE; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

BLOOD PLATELETS; CD40 LIGAND; COLLAGEN; FLAVONOIDS; HSP27 HEAT-SHOCK PROTEINS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; SEROTONIN;

EID: 77953123286     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.12.003     Document Type: Article

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