The acid-mediated intramolecular 1,3-dipolar cycloaddition of derived 2-nitro-1,1-ethenediamines for the synthesis of novel fused bicyclic isoxazoles

Tetrahedron Letters

Volumn 51, Issue 26, 2010, Pages 3388-3391

  Page, Lee W ^a   Bailey, Matthew ^a   Beswick, Paul J ^a   Frydrych, Simon ^a   Gleave, Robert J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

1,3 Dipolar cycloaddition; 2 Nitro 1,1 ethenediamine; 6 Ring fused isoxazole; 7 Ring fused isoxazole; Fused bicyclic isoxazole; Nitrile oxide

Indexed keywords

DIAMINE DERIVATIVE; ISOXAZOLE DERIVATIVE; N METHYL 3 PHENYL 4,5 DIHYDROISOXAZOLO[3,4 C]PYRIDIN 7 AMINE; N METHYL 3 PHENYL 4H PYRROLO[3,4 C]ISOXAZOL 6 AMINE; N METHYL 3 PHENYL 5,6 DIHYDRO 4H ISOXAZOLO[3,4 C]AZEPIN 8 AMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 77953121308     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.04.098     Document Type: Article

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