Generation of a stable anti-human CD44v6 scFv and analysis of its cancer-targeting ability in vitro

Cancer Immunology, Immunotherapy

Volumn 59, Issue 6, 2010, Pages 933-942

  Chen, Yinting ^a   Huang, Kaihong ^a   Li, Xuexian ^a   Lin, Xiangan ^a   Zhu, Zhaohua ^a   Wu, Ying ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cancer targeting; CD44 variant 6; Phage display; Single chain antibody fragment

Indexed keywords

CD44V6 ANTIGEN; NUCLEOTIDE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; EPITOPE; HERMES ANTIGEN; PEPTIDE LIBRARY; TUMOR ANTIGEN;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CANCER CELL; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG TARGETING; FLOW CYTOMETRY; GENE LIBRARY; HEAVY CHAIN; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; LIGHT CHAIN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; WESTERN BLOTTING; ANIMAL; ANTIBODY AFFINITY; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; INTESTINE MUCOSA; METABOLISM; MOLECULAR GENETICS; MOUSE; NEOPLASM; PATHOLOGY; PROTEIN BINDING; PROTEIN ENGINEERING; TUMOR CELL LINE;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS, CD44; ANTIGENS, NEOPLASM; BASE SEQUENCE; CELL LINE, TUMOR; EPITOPES; HUMANS; IMMUNOTHERAPY; INTESTINAL MUCOSA; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN ENGINEERING; SINGLE-CHAIN ANTIBODIES;

EID: 77953093639     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-010-0819-z     Document Type: Article

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