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Volumn 328, Issue 5981, 2010, Pages 1021-1025

The onset of collective behavior in social amoebae

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP PHOSPHODIESTERASE; PROTOZOAL PROTEIN; REGA PROTEIN, DICTYOSTELIUM;

EID: 77953080728     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1183415     Document Type: Article
Times cited : (285)

References (31)
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    • Yamaguchi, S.1
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    • (2004) Science , vol.304 , pp. 875
    • Maeda, M.1
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    • 77953043364 scopus 로고    scopus 로고
    • Materials and Methods are available as supporting material on Science Online.
    • Materials and Methods are available as supporting material on Science Online.
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    • At very low k (flow rates < 1ml/min) the effect of extracellular PDE is nonnegligible. Pulses are no longer observed when dithiothreitol is applied to inhibit extracellular PDE (fig. S2), demonstrating that periodic firing under these conditions depends on degradation of extracellular cAMP by extracellular PDE released by the cells. At higher k, clearing of extracellular cAMP from the medium is mainly determined by dilution.
    • At very low k (flow rates < 1ml/min), the effect of extracellular PDE is nonnegligible. Pulses are no longer observed when dithiothreitol is applied to inhibit extracellular PDE (fig. S2), demonstrating that periodic firing under these conditions depends on degradation of extracellular cAMP by extracellular PDE released by the cells. At higher k, clearing of extracellular cAMP from the medium is mainly determined by dilution.
  • 31
    • 77953080112 scopus 로고    scopus 로고
    • We thank V. O. Nikolaev and M. J. Lohse for providing vector containing Epac1-camps; M Kitahara and E. Hada for technical help, E. C Cox, S. Ishihara, K. Kaneko, H. Kori, and J. Teramae for discussions and suggestions; and the Japan Society for the Promotion of Science (JSPS) postdoctoral fellowship (T.G.), K. Kaneko, and the ERATO-JST for support.
    • We thank V. O. Nikolaev and M. J. Lohse for providing vector containing Epac1-camps; M. Kitahara and E. Hada for technical help, E. C. Cox, S. Ishihara, K. Kaneko, H. Kori, and J. Teramae for discussions and suggestions; and the Japan Society for the Promotion of Science (JSPS) postdoctoral fellowship (T.G.), K. Kaneko, and the ERATO-JST for support.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.