Effect of various risk/benefit trade-offs on parents' understanding of a pediatric research study

Pediatrics

Volumn 125, Issue 6, 2010, Pages

  Tait, Alan R ^a   Zikmund Fisher, Brian J ^a   Fagerlin, Angela ^a   Voepel Lewis, Terri ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Decision making; Numeracy; Pediatric research; Risk benefit trade offs

Indexed keywords

ADULT; ADVERSE DRUG REACTION; ARTICLE; CAUCASIAN; CHILD; CLINICAL EFFECTIVENESS; CLINICAL RESEARCH; CONTROLLED STUDY; DECISION MAKING; DEMOGRAPHY; DRUG SAFETY; EDUCATIONAL STATUS; FEMALE; HEALTH SURVEY; HUMAN; INFORMED CONSENT; INTERNET; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; PAIN ASSESSMENT; PARENT; PEDIATRICS; PERCEPTION; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RESEARCH SUBJECT; RISK BENEFIT ANALYSIS; RISK FACTOR; SOCIAL ASPECT; TREATMENT OUTCOME;

ADULT; BIOMEDICAL RESEARCH; COMPREHENSION; DECISION MAKING; FEMALE; HUMANS; MALE; PARENTS; RISK ASSESSMENT;

EID: 77953078929     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2009-1796     Document Type: Article

References (34)

1. Flory J, Emanuel E. Interventions to improve research participants' understanding in informed consent for research. JAMA. 2004; 202(13):1593-1601 (Pubitemid 39314966)
2. Tait AR, Voepel-Lewis T, Malviya S. Factors that influence parents' assessments of the risks and benefits of research involving their children. Pediatrics. 2004;113(4):727-732 (Pubitemid 38437375)
3. Vallance J, Ahmed M, Dhillon B. Cataract surgery and consent: recall, anxiety, and attitude toward trainee surgeons preoperatively and postoperatively. J Cataract Refract Surg. 2004;30(7):1479-1485 (Pubitemid 38802892)
4. Peters E, Hibbard J, Slovic P, Dieckmann N. Numeracy skill and the communication, comprehension, and use of risk-benefit information. Health Aff (Millwood). 2007; 26(3):741-748
5. Zikmund-Fisher B, Sarr B, Fagerlin A, Ubel P. A matter of perspective: choosing for others differs from choosing for yourself in making treatment decisions. J Gen Intern Med. 2006;21(6):618-622
6. Jonas E, Schultz-Hardt S, Frey D. Giving advice or making decisions in someone else's place: the influence of impression, defense, and accuracy motivation on the search for new information. Pers Soc Psychol Bull. 2005;31(7):977-990
7. Kray L, Gonzalez R. Differential weighting in choice versus advice: I'll do this, you do that. Journal of Behavioral Decision Making. 1999;12(3):207-217
8. Hawley S, Zikmund-Fisher B, Ubel P, Jancovic M, Lucas T, Fagerlin A. The impact of the format of graphical presentation on health-related knowledge and treatment choices. Patient Educ Couns. 2008;73(3):448-455
9. Tait AR, Voepel-Lewis T, Zikmund-Fisher B, Fagerlin A. The effect of format on parents' understanding of the risks and benefits of clinical research: a comparison between text, tables, and graphics. J Health Commun. 2010 (in press)
10. Zikmund-Fisher B, Fagerlin A, Roberts T, Derry H, Ubel P. Alternate methods of framing information about medication side effects: incremental risk versus total risk difference. J Health Commun. 2008;13(2):107-124
11. Waters E, Weinstein N, Colditz G, Emmons K. Formats for improving risk communication in medical tradeoff decision. J Health Commun. 2006;11(2):167-182
12. Edwards A, Elwyn G, Covey J, Matthews E, Pill R. Presenting risk information: a review of the effects of "framing" and other manipulations on patient outcomes. J Health Commun. 2001;6(1):61-82
13. Kahneman D, Slovic P, Tversky A. Judgment Under Uncertainty: Heuristics and Biases. Cambridge, United Kingdom: Cambridge University Press; 1982
14. Kahneman D, Tversky A. Prospect theory: an analysis of decision under risk. Econometrica. 1979;47(2):263-291
15. McNeil B, Pauker S, Sox H Jr, Tversky A. On the elicitation of preferences for alternative therapies. N Engl J Med. 1982;306(21): 1259-1262
16. Rothman A, Martino S, Bedell B, Detweiler J, Salovey P. The systematic influence of gainand loss-framed messages on interest in and use of different types of health behavior. Pers Soc Psychol Bull. 1999;25(1): 1355-1369
17. Forrow L, Taylor W, Arnold R. Absolutely relative: how research results are summarized can affect treatment decisions. Am J Med. 1992;92(2):121-124
18. Malenka D, Baron J, Johansen S, Wahrenberger J, Ross J. The framing effect of relative and absolute risk. J Gen Intern Med. 1993;8(10):543-548
19. Fagerlin A, Zikmund-Fisher B, Ubel P, Jankovic A, Derry H, Smith D. Measuring numeracy without a math test: development of the subjective numeracy scale (SNS). Med Decis Making. 2007;27(5):672-680
20. Zikmund-Fisher B, Smith D, Ubel P, Fagerlin A. A validation of the subjective numeracy scale: effects of low numeracy on comprehension of risk communication and utility elicitations. Med Decis Making. 2007;27(5): 663-671
21. Cacioppo J, Petty R, Kao C. The efficient assessment of need for cognition. J Pers Assess. 1984;48(3):306-307
22. Finucane M, Alhakami A, Slovic P, Johnson S. The affect heuristic in judgments of risks and benefits. Journal of Behavioral Decision Making. 2000;13(1):1-17
23. Peters E, Lipkus I, Diefenbach M. The functions of affect in health communications and the construction of health preferences. Journal of Communication. 2006;56(suppl 1):S40-S62
24. Slovic P, Peters E. Risk perception and af- fect. Current Directions in Psychological Science. 2006;15(6):322-325
25. Kirsch I, Jungelblut A, Jenkins L, Kalstad A. Adult Literacy in America: A First Look at the Results of the Adult National Adult Literacy Survey. Washington, DC: National Center for Education Statistics; 1993
26. Schwartz L, Woloshin S, Black W, Welch H. The role of numeracy in understanding the benefit of screening mammography. Ann Intern Med. 1997;127(11):966-972 (Pubitemid 27516607)
27. Lipkus I, Samsa G, Rimer B. General performance on a numeracy scale among highly educated samples. Med Decis Making. 2001; 21(1):37-44 (Pubitemid 32245029)
28. Woloshin S, Schwartz L. How can we help people make sense of medical data. Eff Clin Pract. 1999;2(4):176-183
29. Davids S, Schapira M, McAuliffe T, Nattinger A. Predictors of pessimistic breast cancer risk perceptions in a primary care population. J Gen Intern Med. 2004;19(4): 310-315 (Pubitemid 38530502)
30. Fagerlin A, Zikmund-Fisher B, Ubel P. How making a risk estimate can change the feel of that risk: shifting attitudes towards breast cancer risk in a general public survey. Patient Educ Couns. 2005;57(3):294-299 (Pubitemid 40694008)
31. Weinfurt K, Castel L, Li Y. The correlation between patient characteristics and expectations of benefit from phase I clinical trials. Cancer. 2003;98(1):166-175 (Pubitemid 36741139)
32. Rajakumar K, Thomas S, Musa D, Alamario D, Garza M. Racial differences in parents' distrust of medicine and research. Arch Pediatr Adolesc Med. 2009;163(2): 108-114
33. Jago A, Vroom V. Predicting leader behavior from a measure of behavioral intent. Acad Manage J. 1978;21(4):715-721
34. Robinson M, Clore G. Simulation, scenarios, and emotional appraisal: testing the convergence of real and imagined reactions to emotional stimuli. Pers Soc Psychol Bull. 2001;27(11):1520-1532 (Pubitemid 33351278)