Torsade de pointes associated with low-dose amisulpride: A case report

Journal of Psychopharmacology

Volumn 24, Issue 3, 2010, Pages 433-435

  Chung, A K K ^a   Chua, S E ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AMISULPRIDE; CHLORPROMAZINE; FLUPENTIXOL; HALOPERIDOL; QUETIAPINE; SULPIRIDE; THIORIDAZINE; ZIPRASIDONE; DRUG DERIVATIVE; NEUROLEPTIC AGENT; SULTOPRIDE;

ADULT; AMENORRHEA; ARTICLE; BLOOD ANALYSIS; CARDIOVASCULAR RISK; CASE REPORT; CLINICAL EXAMINATION; DISEASE ASSOCIATION; DISEASE DURATION; DIZZINESS; DRUG DOSE TITRATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; ELECTROCONVULSIVE THERAPY; EXTRAPYRAMIDAL SYNDROME; FATIGUE; FEMALE; GLASGOW COMA SCALE; HEART ARREST; HEART VENTRICLE FIBRILLATION; HUMAN; HYPERPROLACTINEMIA; INSOMNIA; LOW DRUG DOSE; PARANOID SCHIZOPHRENIA; PATIENT MONITORING; PRIORITY JOURNAL; QT PROLONGATION; RELAPSE; REMISSION; RESUSCITATION; SYNCOPE; TORSADE DES POINTES; UNCONSCIOUSNESS; URINALYSIS; CHEMICALLY INDUCED DISORDER; MIDDLE AGED;

ANTIPSYCHOTIC AGENTS; FEMALE; HUMANS; MIDDLE AGED; SULPIRIDE; TORSADES DE POINTES;

EID: 77953037762     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881108098385     Document Type: Article

References (17)

1. Agelink, MW, Majewski, T, Wurthmann, C, Lukas, K, Ullrich, H, Linka, T, et al. (2001) Effects of newer atypical antipsychotics on autonomic neurocardiac function: a comparison between, amisulpride, olanzapine, sertindole and clozapine. J Clin Psychopharmacol 27: 8-13. (Pubitemid 32096744)
2. American Psychiatric Association. (2004) Practice Guidelines for the Treatment of Patients with Schizophrenia, second ed. http://www. psychiatryonline.com/pracGuide/pracGuideTopie-6,aspx (accessed 22.03.08).
3. De Bruin, ML, Pettersson, M, Meyboom, RHB, Hoes, AW, Leufkens, HGM (2005) Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death. Eur Heart J 26: 590-597. (Pubitemid 40461101)
4. European Medicines Agency (2005) Committee for Proprietary Medicinal Products. The Non-Clinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals. Note for Guidance on the NonClinical Evaluation of the Potential, for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals. http://www.emea.europa.eu/pdfs/human/ich/042302en.pdf (accessed 22.03.08).
5. Gil, FP, Grohmann, R, Ruther, E (2001) Asymptomatic bradycardia associated with amisulpride. Pharmacopsychiatry 34: 259-261.
6. Gupta, A, Lawrence, AT, Krishnan, K, Ravinsky, CJ, Trohman, RG (2007) Current concepts in the mechanisms and management of drug-induced QT prolongation and torsade de pointes. Am Heart J 755: 891-899. (Pubitemid 46809861)
7. Isbister, GK, Murray, L, John, S, Hackett, LP, Haider, T, O'Mullane, P, et al. (2006) Amisulpride deliberate self-poisoning causing severe cardiac toxicity including QT prolongation and torsade de pointes. Med J Aust 184: 354-356.
8. Kongsamut, S, Kang, J, Chen, XL, Roehr, J, Rampe, D (2002) A comparison of the receptor binding and HERG channel, affinities for a series of antipsychotic drugs. Eur J Pharm 450: 37-41.
9. Lynch, MJ, Woods, J, George, N Gerostamoulos, D (2008) Fatality due to amisulpride toxicity: a case report. Med Sci Law 48: 173177.
10. Mago, R (2004) Searching the medical literature for case reports. J Clin Psychiatry 65: 444-445.
11. Naranjo, CA, Busto, U, Sellers, EM, Sandor, P, Ruiz, I, Roberts, EA, et al. (1981) A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30: 239-245. (Pubitemid 12149145)
12. National Institute of Clinical Excellence (2002) Guidance on the Use of Newer (atypical) Antipsychotic Drugs for the Treatment of Schizophrenia, http://www.nice.org.uk/guidance/index.jsp?action=download&o=32378 (accessed. 22.03.08).
13. Sanofl-Aventis (2007) Solian (Amisulpride) Product Insert: SanofiAventis. Hong Kong Limited.
14. Titier, K, Canal, M, Deridet, E, Abouelfath, A, Gromb, S, Molimard, M, et al. (2004) Determination of myocardium to plasma concentration ratios of five antipsychotic drugs: comparison with their ability to induce arrhythmia and sudden death in clinical practice. Toxicol. Appl Pharmacol 799: 52-60. (Pubitemid 39099455)
15. Titier, K, Girodet, P, Verdoux, H, Molimard, M, Begaud, B, Haverkamp, W, et al (2005) Atypical antipsychotics from, potassium, channels to torsade de pointes and sudden death. Drug Saf 28: 35-51.
16. Tracqui, A, Mutter-Schmidt, C, Kintz, P, Berton, C, Mangin, P (1995) Amisulpride poisoning: a report of two cases. Hum Exp Toxicol 14: 294-298.
17. Ward, DI (2005) Two cases of amisulpride overdose: a cause for prolonged QT syndrome. Emerg Med Australas 77; 274-276.