Stiff and tight skin: A rear window into fibrosis without inflammation

Science Translational Medicine

Volumn 2, Issue 23, 2010, Pages

  Avvedimento, Enrico V ^a   Gabrielli, Armando ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; FIBRILLIN 1; FIBRONECTIN; LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VITRONECTIN RECEPTOR;

AUTOIMMUNE DISEASE; CELL DEATH; ECTOPIA LENTIS; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR MATRIX; FIBRILLIN 1 GENE; GENE; GENE MUTATION; HUMAN; INFLAMMATION; MARFAN SYNDROME; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; SHORT SURVEY; SKIN FIBROSIS; SKIN TIGHTNESS; STIFF SKIN SYNDROME; SYSTEMIC SCLEROSIS;

ANIMALS; EXTRACELLULAR MATRIX; FIBROSIS; HUMANS; INFLAMMATION; MARFAN SYNDROME; MICE; MICROFILAMENT PROTEINS; SKIN; SKIN DISEASES; SMAD PROTEINS;

EID: 77953037522     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3000949     Document Type: Short Survey

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22. We thank F. Ramirez, D. Rifkin, and S. M. Aloj for critical reading of the text and helpful discussions; A. Porcellini for help in assembly of the figure; and the Associazione Italiana Ricerca contro il Cancro for support. The authors declare no competing interests.