Donor CD8 T cell activation is critical for greater renal disease severity in female chronic graft-vs.-host mice and is associated with increased splenic ICOShi host CD4 T cells and IL-21 expression

Clinical Immunology

Volumn 136, Issue 1, 2010, Pages 61-73

  Foster, Anthony D ^a   Haas, Mark ^b   Puliaeva, Irina ^a   Soloviova, Kateryna ^a   Puliaev, Roman ^a   Via, Charles S ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b Edars Sinai Medical Center   (United States)

Author keywords

CD8 T cells; Glomerulonephritis; Graft vs. host disease; Lupus

Indexed keywords

DNA ANTIBODY; INDUCIBLE COSTIMULATOR PROTEIN; INTERLEUKIN 21; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC GRAFT VERSUS HOST DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; EFFECTOR CELL; FEMALE; GENE EXPRESSION; HELPER CELL; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; LYMPHOCYTE DEPLETION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEINURIA; SEX DIFFERENCE;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; B-LYMPHOCYTES; BLOOD UREA NITROGEN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COUNT; CHOLESTEROL; FEMALE; GENE EXPRESSION; GLOMERULONEPHRITIS, MEMBRANOUS; GRAFT VS HOST DISEASE; IMMUNOGLOBULIN G; INTERLEUKINS; KIDNEY; LUPUS NEPHRITIS; LYMPHOCYTE DEPLETION; MALE; MICE; MICE, INBRED DBA; MICE, INBRED STRAINS; PROTEINURIA; SERUM ALBUMIN; SEX CHARACTERISTICS; SPLEEN; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER; TRIGLYCERIDES;

EID: 77953020478     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.01.005     Document Type: Article

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