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Volumn 63, Issue 5, 2010, Pages 808-812

Synthesis and biological evaluation of a new family of constrained azabicyclic homocholine analogues

Author keywords

[No Author keywords available]

Indexed keywords

AZABICYCLIC RING; BIOLOGICAL ASSAYS; BIOLOGICAL EVALUATION; CARBOCYCLIC RINGS; CYCLIC KETONES; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR); RECEPTOR TARGETS; SIDE-CHAIN; STRUCTURAL DIVERSITY; SYNTHETIC ROUTES;

EID: 77953015801     PISSN: 00049425     EISSN: None     Source Type: Journal    
DOI: 10.1071/CH10024     Document Type: Conference Paper
Times cited : (3)

References (18)
  • 1
    • 0029739680 scopus 로고    scopus 로고
    • doi:10.1023/ A: 1016091631721
    • A. M. Clark, Pharm. Res. 1996, 13, 1133. doi:10.1023/ A:1016091631721
    • (1996) Pharm. Res. , vol.13 , pp. 1133
    • Clark, A.M.1
  • 3
    • 0042844744 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the period 1981-2002
    • DOI 10.1021/np030096l
    • D. J. Newman, G. M. Cragg, K. M. Snader, J. Nat. Prod. 2003, 66, 1022. doi:10.1021/NP030096L (Pubitemid 36909859)
    • (2003) Journal of Natural Products , vol.66 , Issue.7 , pp. 1022-1037
    • Newman, D.J.1    Cragg, G.M.2    Snader, K.M.3
  • 5
    • 0033964077 scopus 로고    scopus 로고
    • doi:10.1016/ S0301-0082(99) 00045-53
    • D. Paterson, A. Nordberg, Prog. Neurobiol. 2000, 61, 75. doi:10.1016/ S0301-0082(99)00045-53
    • (2000) Prog. Neurobiol. , vol.61 , pp. 75
    • Paterson, D.1    Nordberg, A.2
  • 11
    • 33746917485 scopus 로고    scopus 로고
    • Double-Mannich annulation of cyclic ketones using N,N-bis(ethoxymethyl) alkylamine reagents
    • DOI 10.1021/ol061242s
    • J. I. Halliday, M. Chebib, P. Turner, M. D. McLeod, Org. Lett. 2006, 8, 3399. doi:10.1021/OL061242S (Pubitemid 44187463)
    • (2006) Organic Letters , vol.8 , Issue.15 , pp. 3399-3401
    • Halliday, J.I.1    Chebib, M.2    Turner, P.3    McLeod, M.D.4
  • 12
    • 77952972214 scopus 로고    scopus 로고
    • 13C NMR spectra for all new compounds are reported in the Accessory Publication
    • 13C NMR spectra for all new compounds are reported in the Accessory Publication.
  • 14
    • 0343052529 scopus 로고    scopus 로고
    • Structural study of 3-azabicyclo[3.3.1]nonane derivatives functionalized at 1 and/or 9-positions by molecular mechanics calculations and NMR spectroscopy
    • DOI 10.1016/S0040-4020(97)00832-6, PII S0040402097008326
    • M. S. Arias-Pérez, A. Alejo, A. Maroto, Tetrahedron 1997, 53, 13099. doi:10.1016/S0040-4020(97)00832-6 (Pubitemid 27380435)
    • (1997) Tetrahedron , vol.53 , Issue.38 , pp. 13099-13110
    • Arias-Perez, Ma.S.1    Alejo, A.2    Maroto, A.3
  • 15
    • 45949121333 scopus 로고
    • doi:10.1016/ S0040-4039(00) 95769-95771
    • S. Ram, L. D. Spicer, Tetrahedron Lett. 1987, 28, 515. doi:10.1016/ S0040-4039(00)95769-95771
    • (1987) Tetrahedron Lett. , vol.28 , pp. 515
    • Ram, S.1    Spicer, L.D.2
  • 16
    • 0025142350 scopus 로고
    • Reductive amination of aldehydes and ketones by using sodium triacetoxyborohydride
    • DOI 10.1016/S0040-4039(00)97905-X
    • A. F. Abdel-Magid, C. A. Maryanoff, K. G. Carson, Tetrahedron Lett. 1990, 31, 5595. doi:10.1016/S0040-4039(00)97905-X (Pubitemid 20278604)
    • (1990) Tetrahedron Letters , vol.31 , Issue.39 , pp. 5595-5598
    • Abdel-Magid, A.F.1    Maryanoff, C.A.2    Carson, K.G.3
  • 17
    • 77953011506 scopus 로고    scopus 로고
    • The Ki determinations and receptor binding profiles were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program, Contract # HHSN-271-2008-00025-C (NIMH PDSP). The NIMH PDSP is Directed by Bryan L. Roth MD, PhD at the University of North Carolina at Chapel Hill and Project Officer Jamie Driscol at NIMH, Bethesda MD, USA. For experimental details please refer to the PDSP website and click on "Binding Assay" on the menu bar (accessed January 7, 2010)
    • The Ki determinations and receptor binding profiles were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program, Contract # HHSN-271-2008-00025-C (NIMH PDSP). The NIMH PDSP is Directed by Bryan L. Roth MD, PhD at the University of North Carolina at Chapel Hill and Project Officer Jamie Driscol at NIMH, Bethesda MD, USA. For experimental details please refer to the PDSP website http://pdsp.med.unc.edu/ and click on "Binding Assay" on the menu bar (accessed January 7, 2010).
  • 18
    • 77952971320 scopus 로고    scopus 로고
    • The inhibitory concentration (IC50) response curves for each receptor subtype are reported in the Accessory Publication
    • The inhibitory concentration (IC50) response curves for each receptor subtype are reported in the Accessory Publication.


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