Bis-8-hydroxyquinoline and bis-8-hydroxyquinaldine N-substituted amines: A single methyl group structural difference between the two heterocycles, which modulates the antiproliferative effects

Journal of Heterocyclic Chemistry

Volumn 47, Issue 3, 2010, Pages 719-723

  Madonna, Sébastien ^a   Marcowycz, Aline ^b   Lamoral Theys, Delphine ^b   Van Goietsenoven, Gwendoline ^b   Dessolin, Jean ^c   Pirker, Christine ^d   Spiegl Kreinecker, Sabine ^e   Biraboneye, César Alain ^a   Berger, Walter ^d   Kiss, Robert ^b   Krausa, Jean Louis ^a  

^a CNRS   (France)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c CNRS   (France)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e KEPLER UNIVERSITY HOSPITAL   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

5 (CHLOROMETHYL) 2 METHYLQUINOLIN 8 OL HYDROCHLORIDE; 5,5' (3,5 BIS(TRIFLUOROMETHYL)BENZYLAZANEDIYL)BIS(METHYLENE)DIQUINOLINE 8OL; 5,5' (4 (TRIFLUOROMETHYL)BENZYLAZANEDIYL)BIS(METHYLENE)BIS (2 METHYLQUINOLIN 8 OL); 5,5' (THIOPHEN 2 YLMETHYLAZANEDIYL)BIS(METHYLENE)DIQUINALDINE 8 OL; 5,5' (THIOPHEN 2 YLMETHYLAZANEDIYL)BIS(METHYLENE)DIQUINOLIN 8 OL; 5,5'' (3,5 BIS(TRIFLUOROMETHYL)BENZYLAZANEDIYL)BIS(METHYLENE)DIQUINOLINE 8OL; AMINE; ANTINEOPLASTIC AGENT; FUSED HETEROCYCLIC RINGS; METHYL GROUP; QUINALDINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PHYSICAL CHEMISTRY;

EID: 77953013023     PISSN: 0022152X     EISSN: 19435193     Source Type: Journal    
DOI: 10.1002/jhet.304     Document Type: Article

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