Genomic change of chromosome 8 predicts the response to taxane-based neoadjuvant chemotherapy in node-positive breast cancer

Oncology Reports

Volumn 24, Issue 1, 2010, Pages 121-128

  Han, Sehwan ^a   Park, Kyeongmee ^a   Shin, Eunah ^a   Kim, Hyun Jung ^a   Kim, Jung Yeon ^a   Kim, Ji Young ^a   Gwak, Geumhee ^a  

^a Inje University College of Medicine   (South Korea)

Author keywords

Array based comparative genomic hybridization; Breast cancer; Chemotherapy; Response

Indexed keywords

DOCETAXEL; EPIRUBICIN; ANTINEOPLASTIC AGENT; PHARMACOLOGICAL BIOMARKER; TAXOID;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER PATIENT; CHROMOSOME 13Q; CHROMOSOME 17P; CHROMOSOME 20Q; CHROMOSOME 8; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CLONE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DRUG RESPONSE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE CLUSTER; GENE DELETION; GENE IDENTIFICATION; GENOME; GENOMICS; HUMAN; HUMAN TISSUE; MULTIPLE CYCLE TREATMENT; PHYLOGENETIC TREE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; ADJUVANT THERAPY; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHEMICALLY INDUCED; COPY NUMBER VARIATION; DRUG EFFECTS; EVALUATION STUDY; FEMALE; GENETIC ASSOCIATION; GENETICS; LYMPH NODE; LYMPH NODE METASTASIS; METABOLISM; PATHOLOGY; PROCEDURES; PROGNOSIS;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOMARKERS, PHARMACOLOGICAL; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 8; COMPARATIVE GENOMIC HYBRIDIZATION; DNA COPY NUMBER VARIATIONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENOME; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; NEOADJUVANT THERAPY; PROGNOSIS; RETROSPECTIVE STUDIES; TAXOIDS;

EID: 77952970577     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000836     Document Type: Article

References (39)

1. Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000.
2. Albertson DG and Pinkel D: Genomic microarrays in human genetic disease and cancer. Hum Mol Genet 2: R145-R152, 2003. (Pubitemid 37259326)
3. Climent J, Martinez-Climent JA, Blesa D, et al: Genomic loss of 18p predicts an adverse clinical outcome in patients with highrisk breast cancer. Clin Cancer Res 8: 3863-3869, 2002. (Pubitemid 35424781)
4. Climent J, Dimitrow P, Fridlyand J, et al: Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer. Cancer Res 67: 818-826, 2007. (Pubitemid 46192223)
5. Callagy G, Pharoah P, Chin SF, Sangan T, Daigo Y, Jackson L and Caldas C: Identification and validation of prognostic markers in breast cancer with the complementary use of array- CGH and tissue microarrays. J Pathol 205: 388-396, 2005. (Pubitemid 40253928)
6. Chin K, Devries S, Fridlyand J, et al: Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10: 529-541, 2006. (Pubitemid 44854748)
7. Isola JJ, Kallioniemi OP, Chu LW, Fuqua SA, Hilsenbeck SG, Osborne CK and Waldman FM: Genetic aberrations detected by comparative genomic hybridization predict outcome in nodenegative breast cancer. Am J Pathol 147: 905-911, 1995.
8. Hermsen MA, Baak JP, Meijer GA, Weiss JM, Walboomers JW, Snijders PJ and van Diest PJ: Genetic analysis of 53 lymph node-negative breast carcinomas by CGH and relation to clinical, pathological, morphometric, and DNA cytometric prognostic factors. J Pathol 186: 356-362, 1998.
9. Jones C, Foschini MP, Chaggar R, Lu YJ, Wells D, Shipley JM, Eysebi V and Lakhani SR: Comparative genomic hybridizarion analysis of myoepithelial carcinoma of the breast. Lab Invest 80: 831-836, 2000. (Pubitemid 30421800)
10. Fung LF, Wong N, Tang N, et al: Genetic imbalances in pT2 breast cancers of southern Chinese women. Cancer Genet Cytogenet 124: 56-61, 2001. (Pubitemid 32103266)
11. Aubele M, Cummings M, Walsch A, Zitzelsberger H, Nahrig J, Hofler H and Werner M: Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma. Anal Cell Pathol 20: 17-24, 2000.
12. Climent J, Garcia JL, Mao JH, Arsuaga J and Perez-Losada J: Characterization of breast cancer by array comparative genomic hybridization. Biochem Cell Biol 85: 497-508, 2007. (Pubitemid 47518044)
13. Dellas A, Torhorst J, Schultheiss E, Mihatsch MJ and Moch H: DNA sequence losses on chromosomes 11pand 18q are associated with clinical outcome in lymph node-negative ductal breast cancer. Clin Cancer Res 8: 1210-1216, 2002. (Pubitemid 34517660)
14. Hislop RG, Pratt N, Stocks SC, Steel CM, Sales M, Goudie D, Robertson A and Thompson AM: Karyotypic aberrations of chromosomes 16 and 17 are related to survival in patients with breast cancer. Br J Surg 89: 1581-1586, 2002. (Pubitemid 35404329)
15. Zudaire I, Odero MD, Caballero C, Valenti C, Martinez-Penuela JM, Isola J and Calasanz MJ: Genomic imbalances detected by comparative genomic hybridization are prognostic markers in invasive ductal breast carcinomas. Histopathology 40: 547-555, 2002. (Pubitemid 34621813)
16. Cingoz S, Altungoz O, Canda T, Saydam S, Aksakoglu G and Sakizli M: DNA copy number changes detected by comparative genomic hybridization and their association with clinico-pathologic parameters in breast tumors. Cancer Genet Cytogenet 145: 108-114, 2003. (Pubitemid 36993740)
17. Diallo R, Schaefer KL, Bankfalvi A, et al: Secretory carcinoma of the breast: a distinct variant of invasive ductal carcinoma assessed by comparative genomic hybridization and immunohistochemistry. Hum Pathol 34: 1299-1305, 2003. (Pubitemid 38018144)
18. Janssen EA, Baak JP, Guervo MA, van Diest PJ, Jiwa M and Hermsen MA: In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumor diameter, and oestrogen receptor. J Pathol 201: 555-561, 2003.
19. Weber-Mangal S, Sinn HP, Popp S, et al: Breast cancer in young women (< or = 35 years): Genomic aberrations detected by comparative genomic hybridization. Int J Cancer 107: 583-592, 2003. (Pubitemid 37296119)
20. Jones C, Ford E, Gillet C, et al: Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. Clin Cancer Res 10: 5988-5997, 2004. (Pubitemid 39287503)
21. Fridlyand J, Snijders AM, Ylstra B, et al: Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer 6: 96, 2006.
22. Pinkel D and Albertson DG: Array comparative genomic hybridization and its applications in cancer. Nat Genet 37 (Suppl.): S11-S17, 2005. (Pubitemid 40770398)
23. Pinkel D and Albertson DG: Comparative genomic hybridization. Annu Rev Genomics Hum Genet 6: 331-354, 2005.
24. Frijters ACJ, Zhang Z, van Damme M, Wang GL, Ronald PC and Michelmore RW: Construction of a bacterial artificial chromosome library containing large EcoRI and HindIII genomic fragments of lettuce. Theor Appl Genet 94: 390-399, 1997. (Pubitemid 27164901)
25. Do JH, Kim IS, Park TK and Choi DK: Genome-wide examination of chromosomal aberrations in neuroblastoma SH-SY cells by array-based comparative genomic hybridization. Moll Cells 24: 105-112, 2007.
26. Adhikary S and Eilers M: Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6: 635-645, 2005. (Pubitemid 41081267)
27. Bergamaschi A, Kim YH, Wang P, Sorlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Borresen-Dale AL and Pollack JR: Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer. Genes Chromosomes Cancer 45: 1033-1040, 2006. (Pubitemid 44435537)
28. Pollack JR, Sorlie T, Perou CM, et al: Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci USA 99: 12963-12968, 2002.
29. Yao J, Weremowicz S, Feng B, Gentleman RC, Marks JR, Gelman R, Brennan C and Polak K: Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression. Cancer Res 66: 4065-4078, 2006.
30. Davies SR, Watkins G, Mansel RE and Jiang WG: Differential expression and prognostic implications of the CCN family members WISP-1, WISP-2, and WISP-3 in human breast cancer. Ann Surg Oncol 14: 1909-1918, 2007.
31. Xie D, Nakachi K, Wang H, Elashoff R and Koeffler P: Elevated levels of connective tissue growth factor, WISP-1 and CYR61 in primary breast cancers associated with more advanced features. Cancer Res 61: 8917-8923, 2001.
32. Ehlers JP, Worley L, Onken MD and Harbour JW: DDEF1 is located in an amplified region of chromosome 8q and is over-expressed in uveal melanoma. Clin Cancer Res 11: 3609-3613, 2005. (Pubitemid 40685575)
33. Ray ME, Yang ZQ, Albertson D, Kleer CG, Washburn JG, Macoska JA and Ethier SP: Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines. Cancer Res 64: 40-47, 2004. (Pubitemid 38114080)
34. Prentice LM, Shadeo A, Lestou VS, et al: NRG1 gene rear-rangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis. Oncogene 24: 7281-7289, 2005. (Pubitemid 41622232)
35. Garcia MJ, Pole JC, Chin SF, et al: A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogens. Oncogene 24: 5235-5245, 2005.
36. Nessling M, Richter K, Schwaenen C, Wrobel G, Wessendorf S, Fritz B, Bentz M, Sinn HP, Radlwimmer B and Lichter P: Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue. Cancer Res 65: 439-447, 2005.
37. Park K, Kim J, Lim S and Han S: Topoisomerase II-a (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy. Eur J Cancer 39: 631-634, 2003. (Pubitemid 36287375)
38. Park K, Kwak K, Kim J, Lim S and Han S: c-myc amplification is associated with HER2 amplification and closely linked with cell proliferation in tissue microarray of nonselected breast cancers. Hum Pathol 36: 634-639, 2005. (Pubitemid 40922569)
39. Pierga JY, Reis-Filho JS, Cleator SJ, et al: Microarray-based comparative genomic hybridization of breast cancer patients receiving neoadjuvant chemotherapy. Br J Cancer 96: 341-351, 2007.