-
1
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
DOI 10.1038/nrd1691
-
Wang D and Lippard SJ: Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 4: 307-320, 2005. (Pubitemid 41130944)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
2
-
-
0028718808
-
Mechanisms of acquired resistance to cisplatin
-
Andrews PA: Mechanisms of acquired resistance to cisplatin. Cancer Treat Res 73: 217-248, 1994.
-
(1994)
Cancer Treat Res
, vol.73
, pp. 217-248
-
-
Andrews, P.A.1
-
3
-
-
33846404174
-
Molecular mechanisms of resistance and toxicity associated with platinating agents
-
DOI 10.1016/j.ctrv.2006.09.006, PII S030573720600171X
-
Rabik CA and Dolan ME: Molecular mechanisms of resistance and toxicity associated with platinating agents. Cancer Treat Rev 33: 9-23, 2007. (Pubitemid 46137553)
-
(2007)
Cancer Treatment Reviews
, vol.33
, Issue.1
, pp. 9-23
-
-
Rabik, C.A.1
Dolan, M.E.2
-
4
-
-
0030064573
-
Insights into mechanisms of cisplatin resistance and potential for its clinical reversal
-
Gosland M, Lum B, Schimmelpfennig J, Baker J and Doukas M: Insights into mechanisms of cisplatin resistance and potential for its clinical reversal. Pharmacotherapy 16: 16-39, 1996. (Pubitemid 26033168)
-
(1996)
Pharmacotherapy
, vol.16
, Issue.1 I
, pp. 16-39
-
-
Gosland, M.1
Lum, B.2
Schimmelpfennig, J.3
Baker, J.4
Doukas, M.5
-
5
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
Siddik ZH: Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22: 7265-7279, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
6
-
-
33947320115
-
Platinum drug effects on the expression of genes in the polyamine pathway: Time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells
-
DOI 10.1007/s00280-006-0325-3
-
Varma R, Hector S, Greco WR, Clark K, Hawthorn L, Porter C and Pendyala L: Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells. Cancer Chemother Pharmacol 59: 711-723, 2007. (Pubitemid 46440593)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.59
, Issue.6
, pp. 711-723
-
-
Varma, R.1
Hector, S.2
Greco, W.R.3
Clark, K.4
Hawthorn, L.5
Porter, C.6
Pendyala, L.7
-
7
-
-
4444295545
-
1- acetyltransferase
-
1-acetyltransferase. Mol Cancer Ther 3: 813-822, 2004.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 813-822
-
-
Hector, S.1
Porter, C.W.2
Kramer, D.L.3
Clark, K.4
Prey, J.5
Kisiel, N.6
Diegelman, P.7
Chen, Y.8
Pendyala, L.9
-
8
-
-
45849107868
-
Platinum drug effects on polyamine enzymes in A2780 human ovarian carcinoma cells
-
Abs 365
-
Tummala R, Porter CW, Diegelman P, Vujcic S, Clark K, Prey J, Kisiel N, Kramer D and Pendyala L: Platinum drug effects on polyamine enzymes in A2780 human ovarian carcinoma cells. Proc Am Assoc Cancer Res 48: Abs 365, 2007.
-
(2007)
Proc Am Assoc Cancer Res
, vol.48
-
-
Tummala, R.1
Porter, C.W.2
Diegelman, P.3
Vujcic, S.4
Clark, K.5
Prey, J.6
Kisiel, N.7
Kramer, D.8
Pendyala, L.9
-
9
-
-
0035099627
-
Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
-
Thomas T and Thomas TJ: Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 58: 244-258, 2001. (Pubitemid 32217356)
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, Issue.2
, pp. 244-258
-
-
Thomas, T.1
Thomas, T.J.2
-
10
-
-
0023625905
-
Polyamine biosynthetic activity in normal and neoplastic human colorectal tissues
-
DOI 10.1002/1097-0142(19870915)60:6<1275::AID-CNCR2820600619>3.0. CO;2-I
-
Porter C, Herrera-Omelas L, Pera P, Petrelli NF and Mittleman A: Polyamine biosynthetic activity in normal and neoplastic human colorectal tissues. Cancer 60: 1275-1281, 1987. (Pubitemid 17152906)
-
(1987)
Cancer
, vol.60
, Issue.6
, pp. 1275-1281
-
-
Porter, C.W.1
Herrera-Ornelas, L.2
Pera, P.3
Petrelli, N.F.4
Mittelman, A.5
-
11
-
-
0034030477
-
Polyamine profiles in tumor, normal tissue of the homologous breast, blood, and urine of breast cancer sufferers
-
DOI 10.1023/A:1006319818530
-
Leveque J, Foucher F, Bansard JY, Havouis R, Grall JY and Moulinoux JP: Polyamine profiles in tumor, normal tissue of the homologous breast, blood, and urine of breast cancer sufferers. Breast Cancer Res Treat 60: 99-105, 2000. (Pubitemid 30307469)
-
(2000)
Breast Cancer Research and Treatment
, vol.60
, Issue.2
, pp. 99-105
-
-
Leveque, J.1
Foucher, F.2
Bansard, J.-Y.3
Havouis, R.4
Grall, J.-Y.5
Moulinoux, J.-P.6
-
12
-
-
0042229373
-
Development of Polyamine Analogs as Cancer Therapeutic Agents
-
Thomas T, Balabhadrapathruni S, Gallo MA and Thomas TJ: Development of polyamine analogs as cancer therapeutic agents. Oncol Res 13: 123-135, 2002. (Pubitemid 38168454)
-
(2002)
Oncology Research
, vol.13
, Issue.3
, pp. 123-135
-
-
Thomas, T.1
Balabhadrapathruni, S.2
Gallo, M.A.3
Thomas, T.J.4
-
13
-
-
0030659113
-
11 diethylnorspermine in patients with advanced malignancy
-
DOI 10.1023/A:1005827231849
-
Creaven PJ, Perez R, Pendyala L, Meropol NJ, Loewen G, Levine E, Berghorn E and Raghavan D: Unusual central nervous system toxicity in a Phase I study of N1N11 diethylnorspermine in patients with advanced malignancy. Invest New Drugs 15: 227-234, 1997. (Pubitemid 27453877)
-
(1997)
Investigational New Drugs
, vol.15
, Issue.3
, pp. 227-234
-
-
Creaven, P.J.1
Perez, R.2
Pendyala, L.3
Meropol, N.J.4
Loewen, G.5
Levine, E.6
Berghorn, E.7
Raghavan, D.8
-
14
-
-
0035094510
-
11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies
-
11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies. Invest New Drugs 19: 29-39, 2001.
-
(2001)
Invest New Drugs
, vol.19
, pp. 29-39
-
-
Streiff, R.R.1
Bender, J.F.2
-
15
-
-
0036306242
-
11-diethylnorspermine in patients with non-small cell lung cancer
-
11-diethylnorspermine in patients with non-small cell lung cancer. Clin Cancer Res 8: 684-690, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 684-690
-
-
Hahm, H.A.1
Ettinger, D.S.2
Bowling, K.3
Hoker, B.4
Chen, T.L.5
Zabelina, Y.6
Casero, R.A.J.7
-
16
-
-
0346734280
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. Clin Cancer Res 9: 5922-5928, 2001.
-
(2001)
Clin Cancer Res
, vol.9
, pp. 5922-5928
-
-
Wolff, A.C.1
Armstrong, D.K.2
Fetting, J.H.3
Carducci, M.K.4
Riley, C.D.5
Bender, J.F.6
Casero, R.A.J.7
Davidson, N.E.8
-
17
-
-
45849100196
-
11-diethylnorspermine
-
11-diethylnorspermine. Cancer Chemother Pharmacol 62: 517-527, 2008.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 517-527
-
-
Hector, S.1
Tummala, R.2
Kisiel, N.D.3
Diegelman, P.4
Vujcic, S.5
Clark, K.6
Fakih, M.7
Kramer, D.L.8
Porter, C.W.9
Pendyala, L.10
-
18
-
-
33846786758
-
1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells
-
1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. Mol Cancer Ther 6: 128-137, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 128-137
-
-
Allen, W.L.1
McLean, E.G.2
Boyer, J.3
McCulla, A.4
Wilson, P.M.5
Coyle, V.6
Longley, D.B.7
Casero Jr., R.A.8
Johnston, P.G.9
-
19
-
-
36949000648
-
Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes
-
DOI 10.1021/ja075889z
-
Ray S, Mohan R, Singh JK, Samantaray MK, Shaikh MM, Panda D and Ghosh P: Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes. J Am Chem Soc 129: 15042-15053, 2007. (Pubitemid 350237567)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.48
, pp. 15042-15053
-
-
Ray, S.1
Mohan, R.2
Singh, J.K.3
Samantaray, M.K.4
Shaikh, M.M.5
Panda, D.6
Ghosh, P.7
-
20
-
-
3242683430
-
Synthesis, structural, physico-chemical and biological properties of new palladium(II) complexes with 2,6-dimethyl-4-nitropyridine
-
DOI 10.1016/j.jinorgbio.2004.05.008, PII S0162013404001527
-
Kuduk-Jaworska J, Puszko A, Kubiak M and Pelczynska M: Synthesis, structural, physico-chemical and biological properties of new palladium (II) complexes with 2,6-dimethyl-4-nitropyridine. J Inorg Biochem 98: 1447-1456, 2004. (Pubitemid 38951064)
-
(2004)
Journal of Inorganic Biochemistry
, vol.98
, Issue.8
, pp. 1447-1456
-
-
Kuduk-Jaworska, J.1
Puszko, A.2
Kubiak, M.3
Pelczynska, M.4
-
21
-
-
0035205364
-
Synthesis, characterization, DNA binding and cytotoxic studies of platinum(II) and palladium(II) complexes of the 2,2′-bipyridine and an anion of 1,1-cyclobutanedicarboxylic acid
-
DOI 10.1248/cpb.49.1517
-
Mansuri-Torshizi H, Ghadimy S and Akbarzadeh N: Synthesis, characterization, DNA binding and cytotoxic studies of platinum (II) and palladium (II) complexes of the 2,2′-bipyridine and an anion of 1,1-cyclobutanedicarboxylic acid. Chem Pharm Bull 49: 1517-1520, 2001. (Pubitemid 33126576)
-
(2001)
Chemical and Pharmaceutical Bulletin
, vol.49
, Issue.12
, pp. 1517-1520
-
-
Mansuri-Torshizi, H.1
Ghadimy, S.2
Akbarzadeh, N.3
-
22
-
-
33645876182
-
Pt (II) vs Pd (II) polyamine complexes as new anticancer drugs: A structure-activity study
-
Fiuza SM, Amado PJ, Oliveira VA, Sardao VA, Batista de Carvalho LAE and Marques MPM: Pt (II) vs Pd (II) polyamine complexes as new anticancer drugs: a structure-activity study. Lett Drug Des Discov 3:149-151, 2006.
-
(2006)
Lett Drug des Discov
, vol.3
, pp. 149-151
-
-
Fiuza, S.M.1
Amado, P.J.2
Oliveira, V.A.3
Sardao, V.A.4
De Batista Carvalho, L.A.E.5
Marques, M.P.M.6
-
23
-
-
2542477134
-
Cytotoxic activity of metal complexes of biogenic polyamines: Polynuclear platinum(II) chelates
-
DOI 10.1021/jm0311238
-
Teixeira LJ, Seabra M, Reis E, da Cruz MT, de Lima MC, Pereira E, Miranda MA and Marques MP: Cytotoxic activity of metal complexes of biogenic polyamines: polynuclear platinum (II) chelates. J Med Chem 47: 2917-2925, 2004. (Pubitemid 38678513)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.11
, pp. 2917-2925
-
-
Teixeira, L.J.1
Seabra, M.2
Reis, E.3
Da Cruz, M.T.G.4
De Lima, M.C.P.5
Pereira, E.6
Miranda, M.A.7
Marques, M.P.M.8
-
24
-
-
0030991487
-
Palladium(II) compounds with potential antitumour properties and their platinum analogues: A comparative study of the reaction of some erotic acid derivatives with DNA in vitro
-
DOI 10.1016/S0009-2797(97)00022-7, PII S0009279797000227
-
Butour JL, Wimmer S, Wimmer F and Castan P: Palladium(II) compounds with potential antitumour properties and their platinum analogues: a comparative study of the reaction of some orotic acid derivatives with DNA in vitro. Chem Biol Interact 104: 165-178, 1997. (Pubitemid 27263372)
-
(1997)
Chemico-Biological Interactions
, vol.104
, Issue.2-3
, pp. 165-178
-
-
Butour, J.L.1
Wimmer, S.2
Wimmer, F.3
Castan, P.4
-
25
-
-
3843077805
-
Phase II studies of BBR3464, a novel tri-nuclear platinum complex in patients with gastric or gastro-oesophageal adenocarcinoma
-
Jodrell DI, Evans TR, Steward W, Cameron D, Prendiville J, Aschele C, Noberasco C, Lind M, Carmichael J, Dobbs N, Camboni G, Gatti B and De BF: Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma. Eur J Cancer 40: 1872-1877, 2004.
-
(2004)
Eur J Cancer
, vol.40
, pp. 1872-1877
-
-
Jodrell, D.I.1
Evans, T.R.2
Steward, W.3
Cameron, D.4
Prendiville, J.5
Aschele, C.6
Noberasco, C.7
Lind, M.8
Carmichael, J.9
Dobbs, N.10
Camboni, G.11
Gatti, B.12
De, B.F.13
-
26
-
-
35348966192
-
Effect of metal center ib tge antitumor activity of the analogous dinuclear spermine chelates (PdCl2)2(spermine) and (PtCl2)2(spermine)
-
Soares AS, Fiuza SM, Concalves MJ, de Caravalho LAEB, Marques MPM and Urbano AM: Effect of metal center ib tge antitumor activity of the analogous dinuclear spermine chelates (PdCl2)2(spermine) and (PtCl2)2(spermine). Lett Drug Des Discov 4: 460-463, 2007.
-
(2007)
Lett Drug des Discov
, vol.4
, pp. 460-463
-
-
Soares, A.S.1
Fiuza, S.M.2
Concalves, M.J.3
De Caravalho, L.A.E.B.4
Marques, M.P.M.5
Urbano, A.M.6
-
27
-
-
33947320115
-
Platinum drug effects on the expression of genes in the polyamine pathway: Time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells
-
DOI 10.1007/s00280-006-0325-3
-
Varma R, Hector S, Greco WR, Clark K, Hawthorn L, Porter C and Pendyala L: Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells. Cancer Chemother Pharmacol 59: 711-723, 2007. (Pubitemid 46440593)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.59
, Issue.6
, pp. 711-723
-
-
Varma, R.1
Hector, S.2
Greco, W.R.3
Clark, K.4
Hawthorn, L.5
Porter, C.6
Pendyala, L.7
-
28
-
-
40649106953
-
Simultaneous modeling of concentration-effect and time-course patterns in gene expression data from microarrays
-
Brun YF, Varma R, Hector SM, Pendyala L, Tummala R and Greco WR: Simultaneous modeling of concentration-effect and time-course patterns in gene expression data from microarrays. Cancer Genomics Proteomics 5: 43-53, 2008. (Pubitemid 351372036)
-
(2008)
Cancer Genomics and Proteomics
, vol.5
, Issue.1
, pp. 43-53
-
-
Brun, Y.F.1
Varma, R.2
Hector, S.M.3
Pendyala, L.4
Tummala, R.5
Greco, W.R.6
-
31
-
-
0025833516
-
1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines
-
1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines. Cancer Res 51: 3715-3720, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 3715-3720
-
-
Porter, C.W.1
Ganis, B.2
Libby, P.R.3
Bergeron, R.J.4
-
32
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 52: 5115-5118, 1976.
-
(1976)
Anal Biochem
, vol.52
, pp. 5115-5118
-
-
Bradford, M.M.1
-
33
-
-
0034623954
-
1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs
-
DOI 10.1074/jbc.M003270200
-
Vujcic S, Halmekyto M, Diegelman P, Gan G, Kramer DL, Janne J and Porter CW: Effects of conditional overexpression of spermidine/spermine N1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs. J Biol Chem 275: 38319-38328, 2000. (Pubitemid 32009154)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.49
, pp. 38319-38328
-
-
Vujcic, S.1
Halmekyto, M.2
Diegelman, P.3
Gan, G.4
Kramer, D.L.5
Janne, J.6
Porter, C.W.7
-
34
-
-
0025367455
-
Comparison of in vitro anticancer drug screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
-
Rubinstein LV, Shoemaker RH, Paull KD, et al: Comparison of in vitro anticancer drug screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J Natl Cancer Inst 82: 1113-1118, 1990.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1113-1118
-
-
Rubinstein, L.V.1
Shoemaker, R.H.2
Paull, K.D.3
-
35
-
-
0043136753
-
Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling
-
Maxwell P, Longley DB, Latif T, Boyer J, Allen W, Lynch M, McDermott U, Harkin D, Allegra CJ and Johnston PG: Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling. Cancer Res 63: 4602-4606, 2003. (Pubitemid 36951036)
-
(2003)
Cancer Research
, vol.63
, Issue.15
, pp. 4602-4606
-
-
Maxwell, P.J.1
Longley, D.B.2
Latif, T.3
Boyer, J.4
Allen, W.5
Lynch, M.6
McDermott, U.7
Paul Harkin, D.8
Allegra, C.J.9
Johnston, P.G.10
-
36
-
-
33645070534
-
Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer
-
Boyer J, Allen WL, McLean EG, Wilson PM, McCulla A, Moore S, Longley DB, Caldas C and Johnston PG: Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer. Cancer Res 66: 2765-2777, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 2765-2777
-
-
Boyer, J.1
Allen, W.L.2
McLean, E.G.3
Wilson, P.M.4
McCulla, A.5
Moore, S.6
Longley, D.B.7
Caldas, C.8
Johnston, P.G.9
-
37
-
-
0027238083
-
1-acetyltransferase-the turning point in polyamine metabolism
-
1- acetyltransferase-the turning point in polyamine metabolism. FASEB J 7: 653-661, 1993.
-
(1993)
FASEB J
, vol.7
, pp. 653-661
-
-
Casero, R.A.J.1
Pegg, A.E.2
|