Maternal separation produces, and a second separation enhances, core temperature and passive behavioral responses in guinea pig pups

Physiology and Behavior

Volumn 100, Issue 4, 2010, Pages 305-310

  Hennessy, Michael B ^a   Deak, Terrence ^b   Schiml Webb, Patricia A ^a   Carlisle, Cohen W ^a   O'Brien, Erin ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

Author keywords

Acute phase response; Attachment; Core temperature; Fever; Guinea pigs; Maternal separation; Proinflammatory; Sensitization; Sickness; Stress induced sickness behavior

Indexed keywords

ACUTE PHASE RESPONSE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL HOUSING; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORE TEMPERATURE; FEMALE; FEVER; GUINEA PIG; INFLAMMATION; LOCOMOTION; MALE; MATERNAL DEPRIVATION; NONHUMAN; PASSIVE MOVEMENT; PRIORITY JOURNAL; SENSITIZATION; TELEMETRY; TEMPERATURE MEASUREMENT; ANALYSIS OF VARIANCE; ANIMAL; MOTOR ACTIVITY; NEWBORN; PHYSIOLOGY; PSYCHOLOGY; TIME; VOCALIZATION;

ACUTE-PHASE REACTION; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BODY TEMPERATURE; FEVER; GUINEA PIGS; HOUSING, ANIMAL; MATERNAL DEPRIVATION; MOTOR ACTIVITY; TIME FACTORS; VOCALIZATION, ANIMAL;

EID: 77952958697     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2010.02.024     Document Type: Article

References (45)

1. Anisman H., Merali Z., Hayley S. Sensitization associated with stressors and cytokine treatments. Brain Behav Immun 2003, 17:86-93.
2. Barnum C.J., Blandino P., Deak T. Adaptation in the corticosterone and hyperthermic responses to stress following repeated stressor exposure. J Neuroendocrinol 2007, 19:632-642.
3. Baumann H., Gauldie J. The acute phase response. Immunol Today 1994, 15:74-80.
4. Bernheim H.A., Kluger M.J. Fever: effect of drug-induced antipyresis on survival. Science 1976, 193:237-239.
5. Berryman J.C. Guinea pig vocalizations: their structure, causation and function. Zeitschrift Tierpsychol 1976, 41:80-106.
6. Birtchnell J. Early parental death and psychiatric diagnosis. Soc Psychiatry 1972, 7:202-210.
7. Blatteis C.M. Postnatal development of pyrogenic sensitivity in guinea pigs. J Appl Physiol 1975, 39:251-257.
8. Brown G.W., Harris T., Copeland J.R. Depression and loss. Brit J Psychiatry 1977, 130:1-18.
9. Deak T., Bellamy C., Bordner K.A. Protracted increases in core body temperature and interleukin-1 following acute administration of lipopolysaccharide: implications for the stress response. Physiol Behav 2005, 85:296-307.
10. Deak T., Bordner K.A., McElderry N.K., Barnum C.J., Blandino P., Deak M.M., et al. Stress-induced increases in hypothalamic IL-1: a systematic analysis of multiple stressor paradigms. Brain Res Bull 2005, 64:541-556.
11. Deak T., Meriwether J.L., Fleshner M., Spencer R., Abouhamze A., Moldawer L.L., et al. Evidence that brief stress may induce the acute phase response in rats. Amer J Physiol 1997, 273:R1998-R2004.
12. Gillespie C.F., Nemeroff C.B. Corticotropin-releasing factor and the psychobiology of early life stress. Cur Dir Psychol Sci 2007, 16:85-89.
13. Hart B.L. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 1988, 12:123-137.
14. Hashimoto M., Watanabe T., Fujioka T., Tan N., Yamashita H., Nakamura S. Modulating effects of prenatal stress on hyperthermia induced in adult rat offspring by restraint or LPS-induced stress. Physiol Behav 2001, 73:125-132.
15. Hennessy M.B., Deak T., Schiml-Webb P.A. Early attachment-figure separation and increased risk for later depression: potential mediation by proinflammatory processes. Neurosci Biobehav Rev 2010, 34:782-790.
16. Hennessy M.B., Deak T., Schiml-Webb P.A., Barnum C.J. Immune influences on behavior and endocrine activity in early-experience and maternal separation paradigms. Psychoendocrinology research trends 2007, Nova Science Publishers, Hauppauge, NY. M.T. Czerbska (Ed.).
17. Hennessy M.B., Deak T., Schiml-Webb P.A., Wilson S.E., Greenlee T.M., McCall E. Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors. Physiol Behav 2004, 81:5-13.
18. Hennessy M.B., Long S.J., Nigh C.K., Williams M.T., Nolan D.J. Effects of peripherally administered corticotropin-releasing factor (CRF) and a CRF antagonist: does peripheral CRF activity mediate behavior of guinea pig pups during isolation?. Behav Neurosci 1995, 109:1137-1145.
19. Hennessy M.B., Schiml-Webb P.A., Deak T. Separation, sickness, and depression: a new perspective on an old animal model. Cur Dir Psychol Sci 2009, 18:227-231.
20. Hennessy M.B., Schiml-Webb P.A., Miller E.E., Maken D.S., Bullinger K.L., Deak T. Anti-inflammatory agents attenuate the passive responses of guinea pig pups: evidence for stress-induced sickness behavior during maternal separation. Psychoneuroendocrinol 2007, 32:508-515.
21. Kaufman I.C., Rosenblum L.A. The reaction to separation in infant monkeys: anaclitic depression and conservation withdrawal. Psychosom Med 1967, 29:648-675.
22. König B. Maternal activity budget during lactation in species of Caviidae (Cavia porcellus and Galea musteloides). Zeitschrift Tierpsychol 1985, 68:215-230.
23. Kronfol Z. Immune dysregulation in major depression: a critical review of existing evidence. Int J Neuropsychopharmacol 2006, 5:333-343.
24. Maier S.F., Watkins L.R. Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock. Brain Res 1995, 695:279-282.
25. Maier S.F., Watkins L.R. Cytokines for psychologists: implications of bidirectional immune- to-brain communication for understanding behavior, mood, and cognition. Psychol Rev 1998, 105:87-107.
26. McGivern R.F., Zuloaga D.G., Handa R.J. Sex differences in stress-induced hyperthermia in rats: restraint versus confinement. Physiol Behav 2009, 98:416-420.
27. Mineka S., Suomi S.J. Social separation in monkeys. Psychol Bull 1976, 85:1376-1400.
28. Miura H., Ozaki N., Sawada M., Isobe K., Ohta T., Nagatsu T. A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress 2008, 11:198-209.
29. Miyaoka H., Otsubo T., Kamijima K., Ishii M., Onuki M., Mitamura K. Depression from interferon therapy in patients with hepatitis C. Am J Psychiatry 1999, 156:1120.
30. Oka T., Oka K., Hori T. Mechanisms and mediators of psychological stress-induced rise in core temperature. Psychom Med 2001, 63:476-486.
31. A-benzodiazepine receptor complex ligands and stress-induced hyperthermia in singly housed mice. Pharmacol Biochem Behav 2002, 72:179-188.
32. Perkeybile A.M., Schiml-Webb P.A., O'Brien E., Deak T., Hennessy M.B. Anti-inflammatory influences on behavioral, but not cortisol, responses during maternal separation. Psychoneuroendocrinol 2009, 34:1101-1108.
33. Pugh C.R., Nguyen K.T., Gonyea J.L., Fleshner M., Watkins L.R., Maier S.F., et al. Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation. Behav Brain Res 1999, 106:109-118.
34. Raison C.L., Capuron L., Miller A.H. Cytokines sing the blues: Inflammation and the pathogensis of depression. Trends Immunol 2006, 27:24-31.
35. Schiml P.A., Hennessy M.B. Light-dark variation and changes across the lactational period in the behaviors of undisturbed mother and infant guinea pigs. J Comp Psychol 1990, 104:283-288.
36. Schiml-Webb P.A., Deak T., Greenlee T.M., Maken D.S., Hennessy M.B. Alpha-melanocyte stimulating hormone reduces putative stress-induced sickness behaviors in isolated guinea pig pups. Behav Brain Res 2006, 168:326-330.
37. Schmidt E.D., Aguilera G., Binnekade R., Tilders F.J.H. Single administration of interleukin-1 increased corticotropin releasing hormone and corticotropin releasing hormone-receptor mRNA in the hypothalamic paraventricular nucleus which paralleled long-lasting (weeks) sensitization to emotional stressors. Neurosci 2003, 116:275-283.
38. Schulkin J., McEwen B.S., Gold P.W. Allostasis, amygdala, and anticipatory angst. Neurosci Biobehav Rev 1994, 18:385-396.
39. Shen Y., Connor T.J., Nolan Y., Kelly J.P., Leonard B.E. Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat. Life Sci 1999, 65:1773-1786.
40. Spitz R.A. Anaclitic depression: an inquiry into the genesis of psychiatric conditions of early childhood. Psychoanal Study Child 1946, 2:313-342.
41. Vinkers C.H. de Jong, NM, Kalkman CJ, Westphal KGC, van Oorschot R, Olivier B, Korte SM, Groenink L. Stress-induced hyperthermia is reduced by rapid-acting anxiolytic drugs independent of injection stress in rats. Pharmacol Biochem Behav 2009, 93:413-418.
42. Vinkers C.H., Groenink L., van Bogaert M.J.V., Westphal K.G.C., Kalkman C.J., van Oorschot R., et al. Stress-induced hyperthermia and infection-induced fever: two of a kind?. Physiol Behav 2009, 98:37-43.
43. Widom C.S., DuMont K., Czaja S.J. A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grown up. Arch Gen Psychiatry 2007, 64:49-56.
44. Winer B.J. Statistical principles in experimental design 1971, McGraw Hill, New York. 2nd ed.
45. Yirmiya R. Endotoxin produces a depressive-like episode in rats. Brain Res 1996, 711:163-174.