In Vitro optimization of dexamethasone phosphate delivery by iontophoresis

Physical Therapy

Volumn 88, Issue 10, 2008, Pages 1177-1185

  Sylvestre, Jean Philippe ^a   Guy, Richard H ^a   Delgado Charro, M Begoña ^b  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF BATH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; MANNITOL; POTASSIUM ION; SILVER; SILVER CHLORIDE; SODIUM ION;

ANIMAL TISSUE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; ELECTROOSMOSIS; IN VITRO STUDY; ION TRANSPORT; IONTOPHORESIS; NONHUMAN; SWINE;

ADMINISTRATION, CUTANEOUS; ANIMALS; BIOLOGICAL TRANSPORT; DEXAMETHASONE; ELECTROOSMOSIS; GLUCOCORTICOIDS; IONTOPHORESIS; SKIN; SWINE; TISSUE CULTURE TECHNIQUES;

EID: 52049105725     PISSN: 00319023     EISSN: None     Source Type: Journal    
DOI: 10.2522/ptj.20080043     Document Type: Article

References (39)

1. Harmon KG, Hawley C. Physician prescribing patterns of oral corticosteroids for musculoskeletal injuries. J Am Board Fam Pract. 2003;16:209-212.
2. Cole BJ, Schumacher HR Jr. Injectable corticosteroids in modern practice. J Am Acad Orthop Surg. 2005;13:37-46.
3. Ines LP, da Silva JA. Soft tissue injections. Best Pract Res Clin Rheumatol. 2005;19:503-527.
4. Bell AD, Conaway D. Corticosteroid injections for painful shoulders. Int J Clin Pract. 2005;59:1178-1186.
5. Schumacher HR, Chen LX. Injectable corticosteroids in treatment of arthritis of the knee. Am J Med. 2005;118:1208-1214.
6. Goodyear-Smith F, Arroll B. What can family physicians offer patients with carpal tunnel syndrome other than surgery? A systematic review of nonsurgical management. Ann Fam Med. 2004;2:267-273.
7. Hamann H, Hodges M, Evans B. Effectiveness of iontophoresis of anti-inflammatory medications in the treatment of common musculoskeletal inflammatory conditions: a systematic review. Phys Ther Rev. 2006;11:190-194.
8. Banga AK, Panus PC. Clinical applications of iontophoretic devices in rehabilitation medicine. Critical Reviews in Physical and Rehabilitation Medicine. 1998;10:147-179.
9. Petelenz TJ, Buttke JA, Bonds C, et al. Iontophoresis of dexamethasone: laboratory studies. J Control Release. 1992;20:55-66.
10. Kalia YN, Naik A, Garrison J, Guy RH. Iontophoretic drug delivery. Adv Drug Deliv Rev. 2004;56:619-658.
11. Delgado-Charro MB, Guy RH. Transdermal iontophoresis for controlled drug delivery and non-invasive monitoring. S.T.P. Pharma Sciences. 2001;11:403-414.
12. Phipps JB, Gyory JR. Transdermal ion migration. Adv Drug Deliv Rev. 1992;9:137-176.
13. Pikal MJ. The role of electroosmotic flow in transdermal iontophoresis. Adv Drug Deliv Rev. 2001;46:281-305.
14. Pikal MJ, Shah S. Transport mechanisms in iontophoresis, III: an experimental study of the contributions of electroosmotic flow and permeability change in transport of low and high molecular weight solutes. Pharm Res. 1990;7:222-229.
15. Santi P, Guy RH. Reverse iontophoresis: parameters determining electroosmotic flow, I: pH and ionic strength. J Control Release. 1996;38:159-165.
16. Santi P, Guy RH. Reverse iontophoresis, parameters determining electro-osmotic flow, II: electrode chamber formulation. J Control Release. 1996;42:29-36.
17. Harris PR. Iontophoresis: clinical research in musculoskeletal inflammatory conditions. J Orthop Sports Phys Ther. 1982;4:109-112.
18. Bertolucci LE. Introduction of anti-inflammatory drugs by iontophoresis: double blind study. J Orthop Sports Phys Ther. 1982;4:103-108.
19. Pellecchia GL, Hamel H, Behnke P. Treatment of infrapatellar tendinitis: a combination of modalities and transverse friction massage versus iontophoresis. J Sport Rehabil. 1994;3:135-145.
20. Banta CA. A prospective, nonrandomized study of iontophoresis, wrist splinting, and anti-inflammatory medication in the treatment of early-mild carpal tunnel syndrome. J Occup Environ Med. 1994;36:166-173.
21. Schiffman EL, Braun BL, Lindgren BR. Temporomandibular joint iontophoresis: a double-blind randomized clinical trial. J Orofac Pain. 1996;10:157-165.
22. Hasson SM, Wible CL, Reich M, et al. Dexamethasone iontophoresis: effect on delayed muscle soreness and muscle function. Can J Sport Sci. 1992;17:8-13.
23. Neeter C, Thomee R, Silbernagel KG, et al. Iontophoresis with or without dexamethazone in the treatment of acute Achilles tendon pain. Scand J Med Sci Sports. 2003;13:376-382.
24. Nirschl RP, Rodin DM, Ochiai DH, Maartmann-Moe C. Iontophoretic administration of dexamethasone sodium phosphate for acute epicondylitis: a randomized, double-blinded, placebo-controlled study. Am J Sports Med. 2003;31:189-195.
25. Gokoglu F, Findikoglu G, Yorgancioglu ZR, et al. Evaluation of iontophoresis and local corticosteroid injection in the treatment of carpal tunnel syndrome. Am J Phys Med. 2005;84:92-96.
26. Li LC, Scudds RA, Heck CS, Harth M. The efficacy of dexamethasone iontophoresis for the treatment of rheumatoid arthritic knees: a pilot study. Arthritis Care Res. 1996;9:126-132.
27. Gudeman SD, Eisele SA, Heidt RS, et al. Treatment of plantar fasciitis by iontophoresis of 0.4% dexamethasone: a randomized, double-blind, placebo-controlled study. Am J Sports Med. 1997;25:312-316.
28. Reid KI, Dionne RA, Sicard-Rosenbaum L, et al. Evaluation of iontophoretically applied dexamethasone for painful pathologic temporomandibular joints. Oral Surg Oral Med Oral Pathol. 1994;77:605-609.
29. Runeson L, Haker E. Iontophoresis with cortisone in the treatment of lateral epicondylalgia (tennis elbow): a double-blind study. Scand J Med Sci Sports. 2002;12:136-142.
30. Glass JM, Stephen RL, Jacobson SC. The quantity and distribution of radiolabeled dexamethasone delivered to tissue by iontophoresis. Int J Dermatol. 1980;19:519-525.
31. Marro D, Kalia YN, Delgado-Charro MB, Guy RH. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Pharm Res. 2001;18:1701-1708.
32. Scott ER, Phipps B, Gyory R, Padmanabhan RV. Electrotransport system for transdermal delivery: a practical implementation of iontophoresis. In: Wise DL, ed. Handbook of Pharmaceutical Controlled Release Technology. New York, NY: Marcel Dekker Inc; 2000:617-659.
33. Marro D, Guy RH, DelgadoCharro MB. Characterization of the iontophoretic permselectivity properties of human and pig skin. J Control Release. 2001;70:213-217.
34. Ledger PW. Skin biological issues in electrically enhanced transdermal delivery. Adv Drug Deliv Rev. 1992;9:289-307.
35. Anderson CR, Boeh SD, Morris RL, et al. Quantification of total dexamethasone phosphate delivery by iontophoresis. International Journal of Pharmaceutical Compounding. 2003;7:155-159.
36. Mudry B, Carrupt PA, Guy RH, Delgado-Charro MB. Quantitative structure-permeation relationship for iontophoretic transport across the skin. J Control Release. 2007;122:165-172.
37. Mudry B, Guy RH, Delgado-Charro MB. Electromigration of ions across the skin: determination and prediction of transport numbers. J Pharm Sci. 2006;95:561-569.
38. Roberts MS, Lai PM, Cross SE, Yoshida NH. Solute structure as a determinant of iontophoresic transport. In: Potts RO, Guy RH, eds. Mechanisms of Transdermal Drug Delivery. New York, NY: Marcel Dekker Inc; 1997:291-349.
39. Mudry B, Guy RH, Delgado-Charro MB. Prediction of iontophoretic transport across the skin. J Control Release. 2006;111:362-367.