Para-phenylenediamine induced DNA damage and apoptosis through oxidative stress and enhanced caspase-8 and -9 activities in Mardin-Darby canine kidney cells

Toxicology in Vitro

Volumn 24, Issue 4, 2010, Pages 1197-1202

  Chen, S C ^a   Chen, C H ^b   Tioh, Y L ^c   Zhong, P Y ^d   Lin, Y S ^e   Chye, S M ^f  

^a NATIONAL KAOHSIUNG NORMAL UNIVERSITY   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^c University College Tunku Abdul Rahman   (Malaysia)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e FOOYIN UNIVERSITY   (Taiwan)

^f INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

Author keywords

Caspase; DNA damage; Mardin Darby canine kidney cells; Para Phenylenediamine; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; EFFECTOR CASPASE; INITIATOR CASPASE; PHENYLENEDIAMINE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOG; ENZYME ACTIVATION; ENZYME ACTIVITY; GENOTOXICITY; KIDNEY CELL; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASPASE 8; CASPASE 9; CELL LINE; COLORING AGENTS; DNA DAMAGE; DOGS; OXIDATIVE STRESS; PHENYLENEDIAMINES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOXICITY TESTS;

EID: 77952956309     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.02.011     Document Type: Article

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