Pinocembrin protects the neurovascular unit by reducing inflammation and extracellular proteolysis in MCAO rats

Journal of Asian Natural Products Research

Volumn 12, Issue 5, 2010, Pages 407-418

  Gao, Mei ^a   Zhu, Shen Yin ^a,b   Tan, Chu Bing ^a   Xu, Bei ^a   Zhang, Wen Cui ^c   Du, Guan Hua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Extracellular proteolysis; Inflammation; Neurovascular unit; Pinocembrin; Stroke

Indexed keywords

AQUAPORIN 4; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MESSENGER RNA; OCCLUDIN; PINOCEMBRINE; PROTEIN ZO1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN BLOOD VESSEL; BRAIN ISCHEMIA; CAPILLARY; CELL ACTIVATION; CELL SWELLING; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOTHELIUM CELL; GENE EXPRESSION; INFLAMMATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; APOPTOSIS; BRAIN; BRAIN ISCHEMIA; FLAVANONES; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; RATS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

RATTUS;

EID: 77952929011     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2010.485129     Document Type: Article

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