Involvement of glycogen synthase kinase-3β signaling and aberrant nucleocytoplasmic localization of retinoblastoma protein in tumor promotion in a rat two-stage thyroid carcinogenesis model

Experimental and Toxicologic Pathology

Volumn 62, Issue 3, 2010, Pages 269-280

  Ago, Kyohei ^a   Saegusa, Yukie ^a,b   Nishimura, Jihei ^a,b   Dewa, Yasuaki ^a,b   Kemmochi, Sayaka ^a,b   Kawai, Masaomi ^a,b   Harada, Tomoaki ^a   Mitsumori, Kunitoshi ^a   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Cell cycle; Glycogen synthase kinase (GSK) 3 ; Propylthiouracil; Rat; Retinoblastoma (Rb) protein; Thyroid carcinogenesis; Tumor promotion

Indexed keywords

BIS(2 HYDROXYPROPYL)NITROSAMINE; CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE 2; CYCLIN E; GLYCOGEN SYNTHASE KINASE 3BETA; KI 67 ANTIGEN; PROPYLTHIOURACIL; RETINOBLASTOMA PROTEIN; THYROTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER LOCALIZATION; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CELL SUBPOPULATION; CONTROLLED STUDY; HISTOPATHOLOGY; HYPOTHYROIDISM; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; LONG TERM EXPOSURE; MALE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THYROID FOLLICULAR CARCINOMA; THYROTROPIN BLOOD LEVEL; TUMOR GROWTH; TUMOR PROMOTION;

ADENOCARCINOMA, FOLLICULAR; ADENOMA; ANIMALS; CARCINOGENS; CELL CYCLE PROTEINS; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CYTOPLASM; DISEASE MODELS, ANIMAL; GLYCOGEN SYNTHASE KINASE 3; IMMUNOHISTOCHEMISTRY; MALE; NITROSAMINES; PROTEIN TRANSPORT; RATS; RATS, INBRED F344; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; THIOURACIL; THYROID NEOPLASMS;

RATTUS;

EID: 77952889388     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.04.003     Document Type: Article

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