-
1
-
-
33751205030
-
Lapatinib: Current status and future directions in breast cancer
-
Moy B, Goss P: Lapatinib: current status and future directions in breast cancer. Oncologist 2006;11:1047-1057.
-
(2006)
Oncologist
, vol.11
, pp. 1047-1057
-
-
Moy, B.1
Goss, P.2
-
2
-
-
33747146789
-
Lapatinib: A novel EGFR/ HER2 tyrosine kinase inhibitor for cancer
-
Johnston S, Leary A: Lapatinib: a novel EGFR/ HER2 tyrosine kinase inhibitor for cancer. Drugs Today 2006;42:441-453.
-
(2006)
Drugs Today
, vol.42
, pp. 441-453
-
-
Johnston, S.1
Leary, A.2
-
3
-
-
2942592008
-
Dual kinase inhibition in the treatment of breast cancer. Initial experience with the EGFR/ErbB-2 inhibitor lapatinib
-
Burris III HA
-
Burris HA 3rd: Dual kinase inhibition in the treatment of breast cancer. Initial experience with the EGFR/ErbB-2 inhibitor lapatinib. Oncologist 2004; 9(suppl 3):10-15.
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 3
, pp. 10-15
-
-
-
4
-
-
0035476866
-
The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer
-
Rusnak DW, Affleck K, Cockerill SG, et al.: The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Res 2001;61:7196-7203.
-
(2001)
Cancer Res
, vol.61
, pp. 7196-7203
-
-
Rusnak, D.W.1
Affleck, K.2
Cockerill, S.G.3
-
5
-
-
33144481305
-
Lapatinib: A novel dual tyrosine kinase inhibitor with activity in solid tumors
-
Nelson MH, Dolder CR: Lapatinib: a novel dual tyrosine kinase inhibitor with activity in solid tumors. Ann Pharmacother 2006;40:261-269.
-
(2006)
Ann Pharmacother
, vol.40
, pp. 261-269
-
-
Nelson, M.H.1
Dolder, C.R.2
-
6
-
-
1242273590
-
Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016
-
Xia W, Liu LH, Ho P, Spector NL: Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016. Oncogene 2004;23:646-653.
-
(2004)
Oncogene
, vol.23
, pp. 646-653
-
-
Xia, W.1
Liu, L.H.2
Ho, P.3
Spector, N.L.4
-
7
-
-
33746290773
-
Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation
-
Anido J, Scaltriti M, Bech Serra JJ, et al.: Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation. EMBO J 2006;25:3234-3244.
-
(2006)
EMBO J
, vol.25
, pp. 3234-3244
-
-
Anido, J.1
Scaltriti, M.2
Bech Serra, J.J.3
-
8
-
-
33845886440
-
Lapatinib plus capecitabine for HER-2-positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D, et al.: Lapatinib plus capecitabine for HER-2-positive advanced breast cancer. N Engl J Med 2006;355:2733-2743.
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
9
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
Cameron D, Casey M, Press M, et al.: A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat 2008;112:533-534.
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 533-534
-
-
Cameron, D.1
Casey, M.2
Press, M.3
-
10
-
-
52949147180
-
Lapatinib: A dual tyrosine kinase inhibitor for metastatic breast cancer
-
Paul B, Trovato JA, Thompson J: Lapatinib: a dual tyrosine kinase inhibitor for metastatic breast cancer. Am J Health Syst Pharm 2008;65:1703-1710.
-
(2008)
Am J Health Syst Pharm
, vol.65
, pp. 1703-1710
-
-
Paul, B.1
Trovato, J.A.2
Thompson, J.3
-
11
-
-
57149096463
-
Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer
-
Di Leo A, Gomez HL, Aziz Z, et al.: Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer. J Clin Oncol 2008;26:5544-5552.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5544-5552
-
-
Di Leo, A.1
Gomez, H.L.2
Aziz, Z.3
-
12
-
-
65349110371
-
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A German Breast Group 26/Breast International Group 03-05 study
-
Von Minckwitz G, du Bois A, Schmidt M, et al.: Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German Breast Group 26/Breast International Group 03-05 study. J Clin Oncol 2009;27:1999-2006.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1999-2006
-
-
Von Minckwitz, G.1
Du Bois, A.2
Schmidt, M.3
-
13
-
-
65349158268
-
Continuing trastuzumab beyond progression
-
Jahanzeb M: Continuing trastuzumab beyond progression. J Clin Oncol 2009;27:1935-1937.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1935-1937
-
-
Jahanzeb, M.1
-
14
-
-
74549197481
-
Trastuzumab beyond disease progression: Case closed?
-
Valabrega G, Aglietta M: Trastuzumab beyond disease progression: case closed? J Clin Oncol 2009;27:e121-e122.
-
(2009)
J Clin Oncol
, vol.27
-
-
Valabrega, G.1
Aglietta, M.2
-
15
-
-
84930174095
-
Lapatinib (L) plus capecitabine (C) in HER2+ metastatic breast cancer (MBC): Exploratory analyses by prior therapy
-
abstr P-5082
-
Crown J, Casey MA, Cameron D, Newstat B, Stein SH: Lapatinib (L) plus capecitabine (C) in HER2+ metastatic breast cancer (MBC): exploratory analyses by prior therapy. Eur J Cancer 2009; 7(suppl):abstr P-5082.
-
(2009)
Eur J Cancer
, Issue.SUPPL.
, pp. 7
-
-
Crown, J.1
Casey, M.A.2
Cameron, D.3
Newstat, B.4
Stein, S.H.5
-
16
-
-
34247588567
-
Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
-
Scaltriti M, Rojo F, Ocaña A, et al.: Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst 2007;99:628-638.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 628-638
-
-
Scaltriti, M.1
Rojo, F.2
Ocaña, A.3
-
17
-
-
1242273590
-
Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016
-
Xia W, Liu LH, Ho P, Spector NL: Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016. Oncogene 2004;23: 646-653.
-
(2004)
Oncogene
, vol.23
, pp. 646-653
-
-
Xia, W.1
Liu, L.H.2
Ho, P.3
Spector, N.L.4
-
18
-
-
33847013396
-
Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers
-
Xia W, Husain I, Liu L, et al.: Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers. Cancer Res 2007;67:1170-1175.
-
(2007)
Cancer Res
, vol.67
, pp. 1170-1175
-
-
Xia, W.1
Husain, I.2
Liu, L.3
|