Simultaneous determination of memantine and amantadine in human plasma as fluorescein derivatives by micellar electrokinetic chromatography with laser-induced fluorescence detection and its clinical application

Electrophoresis

Volumn 31, Issue 11, 2010, Pages 1903-1911

  Yeh, Hsin Hua ^a   Yang, Yuan Han ^b   Chen, Su Hwei ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

6 carboxyfluorescein N hydroxysuccinimide ester; Alzheimer's disease and Parkinson's disease; Derivatization; Memantine and amantadine; Micellar electrokinetic chromatography

Indexed keywords

AMINES; ELECTRODYNAMICS; ESTERS; LIQUID CHROMATOGRAPHY; NEURODEGENERATIVE DISEASES;

6-CARBOXYFLUORESCEIN N-HYDROXYSUCCINIMIDE ESTER; ALZHEIMER DISEASE AND PARKINSON DISEASE; ALZHEIMERS DISEASE; AMANTADINE; CARBOXYFLUORESCEIN; DERIVATIZATIONS; MEMANTINE; MEMANTINE AND AMANTADINE; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; N-HYDROXYSUCCINIMIDE; PARKINSON'S DISEASE;

NONIONIC SURFACTANTS;

6 CARBOXYFLUORESCEIN N HYDROXYSUCCINIMIDE ESTER; AMANTADINE SULFATE; BORIC ACID; FLUORESCEIN DERIVATIVE; MEMANTINE; POLIDOCANOL; UNCLASSIFIED DRUG; WITGEN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; DERIVATIZATION; DRUG BLOOD LEVEL; DRUG MONITORING; ELECTRIC POTENTIAL; FEMALE; FLUORESCENCE ANALYSIS; HUMAN; LASER INDUCED FLUORESCENCE DETECTION; MALE; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PARKINSON DISEASE; PH; TEMPERATURE;

EID: 77952796442     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201000001     Document Type: Article

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