Reactive oxygen species in the internal spermatic and brachial veins of patients with varicocele-induced infertility

Korean Journal of Urology

Volumn 51, Issue 5, 2010, Pages 348-353

  Yoon, Chang Jin ^a   Park, Hyun Jun ^a   Park, Nam Cheol ^a  

^a Pusan National University School of Medicine   (South Korea)

Author keywords

Infertility; Reactive oxygen species; Varicocele

Indexed keywords

FOLLITROPIN; HORMONE; LUTEINIZING HORMONE; REACTIVE OXYGEN METABOLITE; TESTOSTERONE;

ADULT; ARTICLE; BLOOD SAMPLING; BRACHIAL VEIN; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROL GROUP; CONTROLLED STUDY; DISEASE DURATION; FOLLITROPIN BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; RADIOIMMUNOASSAY; SPECTROPHOTOMETRY; SPERMATIC VEIN; SURGICAL TECHNIQUE; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL; VARICOCELE; VARICOCELECTOMY; VEIN;

EID: 77952786606     PISSN: 20056737     EISSN: 20056745     Source Type: Journal    
DOI: 10.4111/kju.2010.51.5.348     Document Type: Article

References (27)

1. Saypol DC. Varicocele. J Androl 1981;2:61-71.
2. Choi WS, Kim TB, Paick JS, Kim SW. Factors related to improvement or normalization of semen parameters after microsurgical subinguinal varicocelectomy. Korean J Urol 2009;50:39-45.
3. Cho WJ, Yeo MH, You HJ, Chang IY, Moon HY, Kim CS. The expression of p53 and phosphorylation of H2AX in germ cells of varicocele rats. Korean J Urol 2006;47:1354-1360
4. Agarwal A, Saleh RA. Role of oxidants in male infertility: rationale, significance, and treatment. Urol Clin North Am 2002;29: 817-827 (Pubitemid 36015326)
5. Cam K, Simsek F, Yuksel M, Turkeri L, Haklar G, Yalcin S, et al. The role of reactive oxygen species and apoptosis in the pathogenesis of varicocele in a rat model and efficiency of vitamin E treatment. Int J Androl 2004;27:228-233 (Pubitemid 39062084)
6. Celik-Ozenci C, Sahin Z, Ustunel I, Akkoyunlu G, Erdogru T, Korgun ET, et al. The Fas system may have a role in male reproduction. Fertil Steril 2006:85(Suppl 1):1168-1178
7. Gürdal M, Kireççi S, Huri E, Karaman I, Türkeri L. Correlation between duration of varicocele and apoptosis in testicular tissue in an experimental model. Urology 2008;72:933-936
8. Griveau JF, Le Lannou D. Reactive oxygen species and human spermatozoa: physiology and pathology. Int J Androl 1997;20:61-69 (Pubitemid 27390290)
9. Koksal IT, Usta M, Orhan I, Abbasoglu S, Kadioglu A. Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian J Androl 2003;5:95-99 (Pubitemid 36758323)
10. Hendin BN, Kolettis PN, Sharma RK, Thomas AJ Jr, Agarwal A. Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. J Urol 1999;161:1831-1834 (Pubitemid 29420743)
11. Mostafa T, Anis TH, El-Nashar A, Imam H, Othman IA. Varicocelectomy reduces reactive oxygen species levels and increases antioxidant activity of seminal plasma from infertile men with varicocele. Int J Androl 2001;24:261-265 (Pubitemid 34225149)
12. Klein EA, Platz EA, Thompson IM. Abnormalities of the testes and scrotum and their surgical management. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Campbell-Walsh urology. 9th ed. Philadelphia: Saunders; 2007; 3761-3798
13. Sigman M, Jarow JP. Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol 1997;158:605-607 (Pubitemid 27327731)
14. Naughton CK, Nangia AK, Agarwal A. Pathophysiology of varicoceles in male infertility. Hum Reprod Update 2001;7:473-481
15. Weese DL, Peaster ML, Himsl KK, Leach GE, Lad PM, Zimmern PE. Stimulated reactive oxygen species generation in the spermatozoa of infertile men. J Urol 1993;149:64-67 (Pubitemid 23095475)
16. Köksal IT, Tefekli A, Usta M, Erol H, Abbasoglu S, Kadioglu A. The role of reactive oxygen species in testicular dysfunction associated with varicocele. BJU Int 2000;86:549-552
17. Aitken RJ, Irvine DS, Wu FC. Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility. Am J Obstet Gynecol 1991;164:542-551
18. Desai N, Sabanegh E Jr, Kim T, Agarwal A. Free radical theory of aging: implications in male infertility. Urology 2010;75:14-19
19. Santos JH, Meyer JN, Van Houten B. Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondiral DNA damage and apoptosis. Hum Mol Genet 2006; 15:1757-1768 (Pubitemid 43821766)
20. Zirkin BR, Chen H. Regulation of Leydig cell steroidogenic function during aging. Biol Reprod 2000;63:977-981
21. El-Taieb MA, Herwig R, Nada EA, Greilberger J, Marberger M. Oxidative stress and epididymal sperm transport, motility and morphological defects. Eur J Obstet Gynecol Reprod Biol 2009; 144(Suppl 1):S199-203.
22. Shiraishi K, Naito K. Nitric oxide produced in the testis is involved in dilatation of the internal spermatic vein that compromises spermatogenesis in infertile men with varicocele. BJU Int 2007; 99:1086-1090 (Pubitemid 46587921)
23. Pasqualotto FF, Sundaram A, Sharma RK, Borges E Jr, Pasqualotto EB, Agarwal A. Semen quality and oxidative stress scores in fertile and infertile patients with varicocele. Fertil Steril 2008;89:602-607 (Pubitemid 351335033)
24. Villanueva-Diaz CA, Vega-Hernandez EA, Diaz-Perez MA, Echavarria-Sanchez M, Karchmer-Krivitsky S. Sperm dysfunction in subfertile patients with varicocele and marginal semen analysis. Andrologia 1999;31:263-267 (Pubitemid 29446415)
25. Sakamoto H, Ogawa Y, Yoshida H. Relationship between testicular volume and varicocele in patients with infertility. Urology 2008;71:104-109 (Pubitemid 351173256)
26. Pasqualotto FF, Sharma RK, Pasqualotto EB, Agarwal A. Poor semen quality and ROS-TAC scores in patients with idiopathic infertility. Urol Int 2008;81:263-270 (Pubitemid 351335033)
27. Lee SY, Gong EY, Hong CY, Kim KH, Han JS, Ryu JC, et al. ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation. Free Radic Biol Med 2009;47:1591-1600