Paclitaxel acts as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice

Vaccine

Volumn 28, Issue 27, 2010, Pages 4402-4410

  Yuan, Lin ^a   Wu, Lihua ^a   Chen, Jian ^a   Wu, Qiang ^c   Hu, Songhua ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

^c FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

Author keywords

Adjuvant; MicroRNA; Ovalbumin; Paclitaxel; T bet GATA 3; Th1 Th2

Indexed keywords

CONCANAVALIN A; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; MICRORNA; OVALBUMIN; PACLITAXEL; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; FEMALE; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; INTERLEUKIN-10; INTERLEUKIN-12; MICE; MICE, INBRED ICR; OVALBUMIN; PACLITAXEL; POLYMERASE CHAIN REACTION; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77952744020     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.04.046     Document Type: Article

References (43)

1. Singh M., and O'Hagan D.T. Recent advances in veterinary vaccine adjuvants. International Journal for Parasitology 33 May (5-6) (2003) 469-478
2. Medzhitov R., and Janeway C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91 October (3) (1997) 295-298
3. Milgate J., and Roberts D.C.K. The nutritional and biological significance of saponins. Nutrition Research 15 August (8) (1995) 1223-1249
4. Stewart-Tull D. The theory and practical application of adjuvants (1995), John Wiley & Sons, UK
5. O'Hagan D.T., MacKichan M.L., and Singh M. Recent developments in adjuvants for vaccines against infectious diseases. Biomolecular Engineering 18 October (3) (2001) 69-85
6. Bingham J. Taxus brevifolia: clinical gem or endangered species?. Australian Journal of Hospital Pharmacy 24 (1994) 72
7. Wani M., Taylor H., Wall M., Coggon P., and McPhail A. Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of the American Chemical Society 93 9 (1971) 2325-2327
8. Abal M., Andreu J., and Barasoain I. Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action. Current Cancer Drug Targets 3 3 (2003) 193-203
9. Schiff P., Fant J., and Horwitz S. Promotion of microtubule assembly in vitro by taxol. Nature 277 (1979) 665-667
10. Schiff P., and Horwitz S. Taxol stabilizes microtubules in mouse fibroblast cells. Proceedings of the National Academy of Sciences of the United States of America 77 3 (1980) 1561-1565
11. Rowinsky E., and Donehower R. Paclitaxel (taxol). New England Journal of Medicine 332 15 (1995) 1004
12. Dou W.H., Li Y.Q., Dou C.L., and Li W.H. The taxus resources in Shan'xi and its utilization strategies. Shaanxi Forest Science and Technology 4 (1995) 31-35
13. Zagozdzon R., and Golab J. Immunomodulation by anticancer chemotherapy: more is not always better. International Journal of Oncology 18 2 (2001) 417 [Review]
14. Chan O., and Yang L. The immunological effects of taxanes. Cancer Immunology, Immunotherapy 49 4 (2000) 181-185
15. Mullins D., Koci M., Burger C., and Elgert K. Interleukin-12 overcomes paclitaxel-mediated suppression of T-cell proliferation. Immunopharmacology and Immunotoxicology 20 4 (1998) 473-492
16. Sun J., Hu S., and Song X. Adjuvant effects of protopanaxadiol and protopanaxatriol saponins from ginseng roots on the immune responses to ovalbumin in mice. Vaccine 25 6 (2007) 1114-1120
17. Sun H., Ye Y., Pan H., and Pan Y. Adjuvant effect of Panax notoginseng saponins on the immune responses to ovalbumin in mice. Vaccine 22 29-30 (2004) 3882-3889
18. Bustin S. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. Journal of Molecular Endocrinology 25 2 (2000) 169
19. Livak K., and Schmittgen T. Analysis of relative gene expression data using real-time quantitative PCR and the 2 CT method. Methods 25 4 (2001) 402-408
20. Purcell M., Kurath G., Garver K., Herwig R., and Winton J. Quantitative expression profiling of immune response genes in rainbow trout following infectious haematopoietic necrosis virus (IHNV) infection or DNA vaccination. Fish and Shellfish Immunology 17 5 (2004) 447-462
21. Tizard I., and Schubot R. Veterinary immunology: an introduction (1992)
22. Feldmann M. Cell cooperation in the antibody response. Immunology (2000) 121-135
23. Chakir H., Wang H., Lefebvre D., Webb J., and Scott F. T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3. Journal of Immunological Methods 278 1-2 (2003) 157-169
24. Rengarajan J., Szabo S., and Glimcher L. Transcriptional regulation of Th1/Th2 polarization. Immunology Today 21 10 (2000) 479-483
25. Szabo S., Kim S., Costa G., Zhang X., Fathman C., and Glimcher L. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100 6 (2000) 655-669
26. Usui T., Nishikomori R., Kitani A., and Strober W. GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet. Immunity 18 3 (2003) 415-428
27. Tanaka Y., Hamano S., Gotoh K., Murata Y., Kunisaki Y., Nishikimi A., et al. T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2. Nature Immunology 8 10 (2007) 1067-1075
28. Constant S., and Bottomly K. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annual Review of Immunology 15 1 (1997) 297-322
29. Gottwein J., Blanchard T., Targoni O., Eisenberg J., Zagorski B., Redline R., et al. Protective anti-Helicobacter immunity is induced with aluminum hydroxide or complete Freund's adjuvant by systemic immunization. The Journal of Infectious Diseases 184 3 (2001) 308-314
30. Lipford G., Sparwasser T., Zimmermann S., Heeg K., and Wagner H. CpG-DNA-mediated transient lymphadenopathy is associated with a state of Th1 predisposition to antigen-driven responses. The Journal of Immunology 165 3 (2000) 1228
31. Heeger P., Forsthuber T., Shive C., Biekert E., Genain C., Hofstetter H., et al. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. The Journal of Immunology 164 11 (2000) 5771
32. Lindblad E. Aluminium adjuvants-in retrospect and prospect. Vaccine 22 27-28 (2004) 3658-3668
33. Song X., Bao S., Wu L., and Hu S. Ginseng stem-leaf saponins (GSLS) and mineral oil act synergistically to enhance the immune responses to vaccination against foot-and-mouth disease in mice. Vaccine 27 1 (2009) 51-55
34. Sun J., Song X., and Hu S. Ginsenoside Rg1 and aluminum hydroxide synergistically promote immune responses to ovalbumin in BALB/c mice. Clinical and Vaccine Immunology 15 2 (2008) 303
35. Kawasaki K., Akashi S., Shimazu R., Yoshida T., Miyake K., and Nishijima M. Mouse toll-like receptor 4· MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. Journal of Biological Chemistry 275 4 (2000) 2251
36. Ding A., Porteu F., Sanchez E., and Nathan C. Shared actions of endotoxin and taxol on TNF receptors and TNF release. Science 248 4953 (1990) 370
37. Mullins D., Burger C., and Elgert K. Paclitaxel enhances macrophage IL-12 production in tumor-bearing hosts through nitric oxide. The Journal of Immunology 162 11 (1999) 6811
38. Perera P., Mayadas T., Takeuchi O., Akira S., Zaks-Zilberman M., Goyert S., et al. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. The Journal of Immunology 166 1 (2001) 574
39. Shurin G.V., Tourkova I.L., Kaneno R., and Shurin M.R. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism. The Journal of Immunology 183 (2009) 137-144
40. Pedersen I., and David M. MicroRNAs in the immune response. Cytokine 43 (2008) 391-394
41. Rodriguez A., Vigorito E., Clare S., Warren M.V., Couttet P., Soond D.R., et al. Requirement of bic/microRNA-155 for normal immune function. Science 316 (2007) 608-611
42. Taganov K.D., Boldin M.P., Chang K.J., and Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proceedings of the National Academy of Sciences of the United States of America 103 (2006) 12481-12486
43. O'Connell R.M., Taganov K.D., Boldin M.P., Cheng G., and Baltimore D. MicroRNA-155 is induced during the macrophage inflammatory response. Proceedings of the National Academy of Sciences of the United States of America 104 (2007) 1604-1609