Crystal structure of the Ca2+-form and Ca2+-binding kinetics of metastasis-associated protein, S100A4

FEBS Letters

Volumn 582, Issue 12, 2008, Pages 1651-1656

  Gingras, Alexandre R ^a   Basran, Jaswir ^a   Prescott, Andrew ^a   Kriajevska, Marina ^a   Bagshaw, Clive R ^a   Barsukov, Igor L ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Ca2+ binding; Crystal structure; Kinetics; Ligand binding; S100A4; Tyrosine fluorescence

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALVASCULIN; OLIGOMER;

ARTICLE; CALCIUM BINDING; CRYSTAL STRUCTURE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; RESIDUE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CALCIUM; CRYSTALLOGRAPHY, X-RAY; FLUORESCENCE; HUMANS; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; PROTEIN BINDING; PROTEIN CONFORMATION; S100 PROTEINS; TYROSINE;

EID: 43549125729     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.04.017     Document Type: Article

References (21)

1. Donato R. RAGE: a single receptor for several ligands and different cellular responses: the case of certain S100 proteins. Curr. Mol. Med. 7 (2007) 711-724
2. Tarabykina S., Griffiths T.R.L., Tulchinsky E., Mellon J.K., Bronstein I.B., and Kriajevska M. Metastasis-associated protein S100A4: spotlight on its role in cell migration. Curr. Cancer Drug Targets 7 (2007) 217-228
3. Helfman D.M., Kim E.J., Lukanidin E., and Grigorian M. The metastasis associated protein S100A4: role in tumour progression and metastasis. Br. J. Cancer 92 (2005) 1955-1958
4. Garrett S.C., Varney K.M., Weber D.J., and Bresnick A.R. S100A4, a mediator of metastasis. J. Biol. Chem. 281 (2006) 677-680
5. Mejlvang J., Kriajevska M., Berditchevski F., Bronstein I., Lukanidin E.M., Pringle J.H., Mellon J.K., and Tulchinsky E.M. Characterization of E-cadherin-dependent and -independent events in a new model of c-Fos-mediated epithelial-mesenchymal transition. Exp. Cell Res. 313 (2007) 380-393
6. Dulyaninova N.G., Malashkevich V.N., Almo S.C., and Bresnick A.R. Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry 44 (2005) 6867-6876
7. Novitskaya V., Grigorian M., Kriajevska M., Tarabykina S., Bronstein I., Berezin V., Bock E., and Lukanidin E. Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons. J. Biol. Chem. 275 (2000) 41278-41286
8. Kiryushko D., Novitskaya V., Soroka V., Klingelhofer J., Lukanidin E., Berezin V., and Bock E. Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein. Mol. Cell Biol. 26 (2006) 3625-3638
9. Santamaria-Kisiel L., Rintala-Dempsey A.C., and Shaw G.S. Calcium-dependent and -independent interactions of the S100 protein family. Biochem. J. 396 (2006) 201-214
10. Wilder P.T., Lin J., Bair C.L., Charpentier T.H., Yang D., Liriano M., Varney K.M., Lee A., Oppenheim A.B., Adhya S., Carrier F., and Weber D.J. Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B. Biochim. Biophys. Acta 1763 (2006) 1284-1297
11. Dukhanina E.A., Dukhanin A.S., Lomonosov M.Y., Lukanidin E.M., and Georgiev G.P. Spectral studies on the calcium-binding properties of Mts1 protein and its interaction with target protein. FEBS Lett. 410 (1997) 403-406
12. Dutta K., Cox C.J., Huang H., Basavappa R., and Pascal S.M. Calcium coordination studies of the metastatic Mts1 protein. Biochemistry 41 (2002) 4239-4245
13. Garrett S.C., Hodgson L., Rybin A., Toutchkine A., Hahn K.M., Lawrence D.S., and Bresnick A.R. A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics. Biochemistry 47 (2008) 986-996
14. Vallely K.M., Rustandi R.R., Ellis K.C., Varlamova O., Bresnick A.R., and Weber D.J. Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy. Biochemistry 41 (2002) 12670-12680
15. Tarabykina S., Scott D.J., Herzyk P., Hill T.J., Tame J.R., Kriajevska M., Lafitte D., Derrick P.J., Dodson G.G., Maitland N.J., Lukanidin E.M., and Bronstein I.B. The dimerization interface of the metastasis-associated protein S100A4 (Mts1): in vivo and in vitro studies. J. Biol. Chem. 276 (2001) 24212-24222
16. Kabsch W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Crystallogr. 26 (1993) 795-800
17. Murshudov G.N., Vagin A.A., and Dodson E.J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Cryst. D53 (1997) 240-255
18. Laskowski R.A., Macarthur M.W., Moss D.S., and Thornton J.M. PROCHECK - a program to check the stereochemical quality of protein structures. J. Appl. Crystallogr. 26 (1993) 283-291
19. Ostendorp T., Leclerc E., Galichet A., Koch M., Demling N., Weigle B., Heizmann C.W., Kroneck P.M., and Fritz G. Structural and functional insights into RAGE activation by multimeric S100B. EMBO J. 26 (2007) 3868-3878
20. Kriajevska M., Tarabykina S., Bronstein I., Maitland N., Lomonosov M., Hansen K., Georgiev G., and Lukanidin E. Metastasis-associated Mts1 (S100A4) protein modulates protein kinase C phosphorylation of the heavy chain of nonmuscle myosin. J. Biol. Chem. 273 (1998) 9852-9856
21. Bagshaw C.R., and Reed G.H. The significance of the slow dissociation of divalent metal ions from myosin 'regulatory' light chains. FEBS Lett. 81 (1977) 386-390