메뉴 건너뛰기




Volumn 255, Issue 3, 2010, Pages 824-833

Hepatocellular carcinoma: Hepatocyte-selective enhancement at gadoxetic acid-enhanced MR imaging - Correlation with expression of sinusoidal and canalicular transporters and bile accumulation

Author keywords

[No Author keywords available]

Indexed keywords

BILE PIGMENT; GADOXETIC ACID; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1; ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3; UNCLASSIFIED DRUG;

EID: 77952722303     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.10091557     Document Type: Article
Times cited : (235)

References (33)
  • 1
    • 25144495562 scopus 로고    scopus 로고
    • Efficacy and safety of MR imaging with liver-specific contrast agent: U.S. multicenter phase III study
    • Bluemke DA, Sahani D, Amendola M, et al. Efficacy and safety of MR imaging with liver-specific contrast agent: U.S. multicenter phase III study. Radiology 2005;237(1):89-98.
    • (2005) Radiology , vol.237 , Issue.1 , pp. 89-98
    • Bluemke, D.A.1    Sahani, D.2    Amendola, M.3
  • 2
    • 15844425224 scopus 로고    scopus 로고
    • Liver tumors: Comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA
    • Vogl TJ, Kümmel S, Hammerstingl R, et al. Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA. Radiology 1996;200(1):59-67.
    • (1996) Radiology , vol.200 , Issue.1 , pp. 59-67
    • Vogl, T.J.1    Kümmel, S.2    Hammerstingl, R.3
  • 3
    • 41249084500 scopus 로고    scopus 로고
    • Biliary and reticuloendothelial impairment in hepatocarcinogenesis: The diagnostic role of tissue-specific MR contrast media
    • Bartolozzi C, Crocetti L, Lencioni R, Cioni D, Della Pina C, Campani D. Biliary and reticuloendothelial impairment in hepatocarcinogenesis: the diagnostic role of tissue-specific MR contrast media. Eur Radiol 2007;17(10):2519-2530.
    • (2007) Eur Radiol , vol.17 , Issue.10 , pp. 2519-2530
    • Bartolozzi, C.1    Crocetti, L.2    Lencioni, R.3    Cioni, D.4    Della Pina, C.5    Campani, D.6
  • 4
    • 0029003150 scopus 로고
    • Phase I clinical evaluation of Gd-EOB-DTPA as a hepatobiliary MR contrast agent: Safety, pharmacokinetics, and MR imaging
    • Hamm B, Staks T, Mühler A, et al. Phase I clinical evaluation of Gd-EOB-DTPA as a hepatobiliary MR contrast agent: safety, pharmacokinetics, and MR imaging. Radiology 1995;195(3):785-792.
    • (1995) Radiology , vol.195 , Issue.3 , pp. 785-792
    • Hamm, B.1    Staks, T.2    Mühler, A.3
  • 6
    • 0030635909 scopus 로고    scopus 로고
    • Enhancement characteristics of liver metastases, hepatocellular carcinomas, and hemangiomas with Gd-EOB-DTPA: Preliminary results with dynamic MR imaging
    • Reimer P, Rummeny EJ, Daldrup HE, et al. Enhancement characteristics of liver metastases, hepatocellular carcinomas, and hemangiomas with Gd-EOB-DTPA: preliminary results with dynamic MR imaging. Eur Radiol 1997;7(2):275-280.
    • (1997) Eur Radiol , vol.7 , Issue.2 , pp. 275-280
    • Reimer, P.1    Rummeny, E.J.2    Daldrup, H.E.3
  • 7
    • 67049172143 scopus 로고    scopus 로고
    • Gadoxetic acid-enhanced MRI versus triple-phase MDCT for the preoperative detection of hepatocellular carcinoma
    • Kim SH, Kim SH, Lee J, et al. Gadoxetic acid-enhanced MRI versus triple-phase MDCT for the preoperative detection of hepatocellular carcinoma. AJR Am J Roentgenol 2009;192(6):1675-1681.
    • (2009) AJR Am J Roentgenol , vol.192 , Issue.6 , pp. 1675-1681
    • Kim, S.H.1    Kim, S.H.2    Lee, J.3
  • 8
    • 12344296444 scopus 로고    scopus 로고
    • Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: Correlation with histopathologic findings and spiral CT - Initial observations
    • Huppertz A, Haraida S, Kraus A, et al. Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: correlation with histopathologic findings and spiral CT - initial observations. Radiology 2005;234(2):468-478.
    • (2005) Radiology , vol.234 , Issue.2 , pp. 468-478
    • Huppertz, A.1    Haraida, S.2    Kraus, A.3
  • 9
    • 50949093592 scopus 로고    scopus 로고
    • Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: Results of a multicenter trial
    • Zech CJ, Grazioli L, Breuer J, Reiser MF, Schoenberg SO. Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: results of a multicenter trial. Invest Radiol 2008;43(7):504-511.
    • (2008) Invest Radiol , vol.43 , Issue.7 , pp. 504-511
    • Zech, C.J.1    Grazioli, L.2    Breuer, J.3    Reiser, M.F.4    Schoenberg, S.O.5
  • 10
    • 68149084824 scopus 로고    scopus 로고
    • Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma
    • Narita M, Hatano E, Arizono S, et al. Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma. J Gastroenterol 2009;44(7):793-798.
    • (2009) J Gastroenterol , vol.44 , Issue.7 , pp. 793-798
    • Narita, M.1    Hatano, E.2    Arizono, S.3
  • 11
    • 0028438298 scopus 로고
    • Prolonged positive contrast enhancement with Gd-EOB-DTPA in experimental liver tumors potential value in tissue characterization
    • Ni Y, Marchal G, Yu J, Mühler A, Lukito G, Baert AL. Prolonged positive contrast enhancement with Gd-EOB-DTPA in experimental liver tumors: potential value in tissue characterization. J Magn Reson Imaging 1994;4(3):355-363.
    • (1994) J Magn Reson Imaging , vol.4 , Issue.3 , pp. 355-363
    • Ni, Y.1    Marchal, G.2    Yu, J.3    Mühler, A.4    Lukito, G.5    Baert, A.L.6
  • 13
    • 0026712825 scopus 로고
    • Gadoliniumethoxybenzyl-DTPA, a new liver-specific magnetic resonance contrast agent: Kinetic and enhancement patterns in normal and cholestatic rats
    • Clément O, Mühler A, Vexler V, Berthezène Y, Brasch RC. Gadoliniumethoxybenzyl-DTPA, a new liver-specific magnetic resonance contrast agent: kinetic and enhancement patterns in normal and cholestatic rats. Invest Radiol 1992;27(8):612-619.
    • (1992) Invest Radiol , vol.27 , Issue.8 , pp. 612-619
    • Clément, O.1    Mühler, A.2    Vexler, V.3    Berthezène, Y.4    Brasch, R.C.5
  • 14
    • 0034815177 scopus 로고    scopus 로고
    • Abc protein transport of MRI contrast agents in canalicular rat liver plasma vesicles and yeast vacuoles
    • Pascolo L, Petrovic S, Cupelli F, et al. Abc protein transport of MRI contrast agents in canalicular rat liver plasma vesicles and yeast vacuoles. Biochem Biophys Res Commun 2001;282(1):60-66.
    • (2001) Biochem Biophys Res Commun , vol.282 , Issue.1 , pp. 60-66
    • Pascolo, L.1    Petrovic, S.2    Cupelli, F.3
  • 16
    • 0037733365 scopus 로고    scopus 로고
    • A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane
    • König J, Cui Y, Nies AT, Keppler D. A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am J Physiol Gastrointest Liver Physiol 2000;278(1):G156-G164.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278 , Issue.1
    • König, J.1    Cui, Y.2    Nies, A.T.3    Keppler, D.4
  • 17
    • 0034725617 scopus 로고    scopus 로고
    • Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide
    • König J, Cui Y, Nies AT, Keppler D. Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. J Biol Chem 2000;275(30):23161-23168.
    • (2000) J Biol Chem , vol.275 , Issue.30 , pp. 23161-23168
    • König, J.1    Cui, Y.2    Nies, A.T.3    Keppler, D.4
  • 18
    • 29744470059 scopus 로고    scopus 로고
    • Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver
    • Vander Borght S, Libbrecht L, Blokzijl H, et al. Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver. J Pathol 2005;207(4):471-482.
    • (2005) J Pathol , vol.207 , Issue.4 , pp. 471-482
    • Vander Borght, S.1    Libbrecht, L.2    Blokzijl, H.3
  • 20
    • 17044400593 scopus 로고    scopus 로고
    • Hepatobiliary transporter expression in human hepatocellular carcinoma
    • Zollner G, Wagner M, Fickert P, et al. Hepatobiliary transporter expression in human hepatocellular carcinoma. Liver Int 2005;25(2):367-379.
    • (2005) Liver Int , vol.25 , Issue.2 , pp. 367-379
    • Zollner, G.1    Wagner, M.2    Fickert, P.3
  • 21
    • 1642491778 scopus 로고    scopus 로고
    • The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3β in hepatocellular carcinoma
    • Vavricka SR, Jung D, Fried M, Grützner U, Meier PJ, Kullak-Ublick GA. The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3β in hepatocellular carcinoma. J Hepatol 2004;40(2):212-218.
    • (2004) J Hepatol , vol.40 , Issue.2 , pp. 212-218
    • Vavricka, S.R.1    Jung, D.2    Fried, M.3    Grützner, U.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 22
    • 0035889601 scopus 로고    scopus 로고
    • Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma
    • Nies AT, König J, Pfannschmidt M, Klar E, Hofmann WJ, Keppler D. Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma. Int J Cancer 2001;94(4):492-499.
    • (2001) Int J Cancer , vol.94 , Issue.4 , pp. 492-499
    • Nies, A.T.1    König, J.2    Pfannschmidt, M.3    Klar, E.4    Hofmann, W.J.5    Keppler, D.6
  • 23
    • 61949171989 scopus 로고    scopus 로고
    • Pathologic diagnosis of early hepatocellular carcinoma: A report of the International Consensus Group for Hepatocellular Neoplasia
    • International Consensus Group for Hepatocellular Neoplasia
    • International Consensus Group for Hepatocellular Neoplasia. Pathologic diagnosis of early hepatocellular carcinoma: a report of the International Consensus Group for Hepatocellular Neoplasia. Hepatology 2009;49(2):658-664.
    • (2009) Hepatology , vol.49 , Issue.2 , pp. 658-664
  • 25
    • 78651053628 scopus 로고
    • Primary carcinoma of the liver: A study of 100 cases among 48,900 necropsies
    • Edmondson HA, Steiner PE. Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer 1954;7(3):462-503.
    • (1954) Cancer , vol.7 , Issue.3 , pp. 462-503
    • Edmondson, H.A.1    Steiner, P.E.2
  • 26
    • 0033861597 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide-enhanced magnetic resonance images of hepatocellular carcinoma: Correlation with histological grading
    • Imai Y, Murakami T, Yoshida S, et al. Superparamagnetic iron oxide-enhanced magnetic resonance images of hepatocellular carcinoma: correlation with histological grading. Hepatology 2000;32(2):205-212.
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 205-212
    • Imai, Y.1    Murakami, T.2    Yoshida, S.3
  • 27
    • 0026625060 scopus 로고
    • Vascular supply in adenomatous hyperplasia of the liver and hepatocellular carcinoma: A morphometric study
    • Ueda K, Terada T, Nakanuma Y, Matsui O. Vascular supply in adenomatous hyperplasia of the liver and hepatocellular carcinoma: a morphometric study. Hum Pathol 1992;23(6):619-626.
    • (1992) Hum Pathol , vol.23 , Issue.6 , pp. 619-626
    • Ueda, K.1    Terada, T.2    Nakanuma, Y.3    Matsui, O.4
  • 30
    • 0035971239 scopus 로고    scopus 로고
    • Hepatic Uptake of Bilirubin and its Conjugates by the Human Organic Anion Transporter SLC21A6
    • DOI 10.1074/jbc.M004968200
    • Cui Y, König J, Leier I, Buchholz U, Keppler D. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J Biol Chem 2001;276(13): 9626-9630. (Pubitemid 37391856)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.13 , pp. 9626-9630
    • Cui, Y.1    Konig, J.2    Leier, I.3    Buchholz, U.4    Keppler, D.5
  • 31
    • 0032769284 scopus 로고    scopus 로고
    • Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2
    • DOI 10.1002/hep.510300220
    • Kamisako T, Leier I, Cui Y, et al. Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2. Hepatology 1999;30(2):485-490. (Pubitemid 29357515)
    • (1999) Hepatology , vol.30 , Issue.2 , pp. 485-490
    • Kamisako, T.1    Leier, I.2    Gui, Y.3    Konig, J.4    Buchholz, U.5    Hummel-Eisenbeiss, J.6    Keppler, D.7
  • 32
    • 66749184079 scopus 로고    scopus 로고
    • Assessment of hepatic extraction fraction and input relative blood flow using dynamic hepatocyte-specific contrast-enhanced MRI
    • Nilsson H, Nordell A, Vargas R, Douglas L, Jonas E, Blomqvist L. Assessment of hepatic extraction fraction and input relative blood flow using dynamic hepatocyte-specific contrast-enhanced MRI. J Magn Reson Imaging 2009;29(6):1323-1331.
    • (2009) J Magn Reson Imaging , vol.29 , Issue.6 , pp. 1323-1331
    • Nilsson, H.1    Nordell, A.2    Vargas, R.3    Douglas, L.4    Jonas, E.5    Blomqvist, L.6
  • 33
    • 33750610841 scopus 로고    scopus 로고
    • Hepatobiliary transporters and drug-induced cholestasis
    • Pauli-Magnus C, Meier PJ. Hepatobiliary transporters and drug-induced cholestasis. Hepatology 2006;44(4):778-787.
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 778-787
    • Pauli-Magnus, C.1    Meier, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.