Mutation effects on structural stability of polyglutamine peptides by molecular dynamics simulation

Interdisciplinary Sciences – Computational Life Sciences

Volumn 1, Issue 1, 2009, Pages 21-29

  Nakano, Miki ^a   Watanabe, Hirofumi ^a,b   Starikov, E B ^c   Rothstein, Stuart M ^d   Tanaka, Shigenori ^a,b  

^a KOBE UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^d BROCK UNIVERSITY   (Canada)

Author keywords

Huntington's disease; molecular dynamics; polyglutamine; protein aggregation; helix

Indexed keywords

PEPTIDE; POLYGLUTAMINE; PROLINE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENTROPY; GENETICS; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR GENETICS; MUTATION; PROTEIN CONFORMATION; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ENTROPY; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROLINE; PROTEIN CONFORMATION; PROTEIN STABILITY;

EID: 77952692273     PISSN: 19132751     EISSN: 18671462     Source Type: Journal    
DOI: 10.1007/s12539-008-0020-7     Document Type: Article

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