Edaravone directly reacts with singlet oxygen and protects cells from attack

Life Sciences

Volumn 86, Issue 21-22, 2010, Pages 808-813

  Nishinaka, Yoko ^a   Mori, Hiroko ^b   Endo, Nobuyuki ^c   Miyoshi, Takashi ^d   Yamashita, Kouhei ^d   Adachi, Souichi ^a   Arai, Toshiyuki ^d  

^a KYOTO UNIVERSITY   (Japan)

^b Higashiyama Takeda Hospital   (Japan)

^c WAKASA WAN ENERGY RESEARCH CENTER   (Japan)

^d KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Edaravone; Near infrared luminescence; Neuronal cell death; Rose Bengal; Singlet oxygen

Indexed keywords

NORPHENAZONE; ROSE BENGAL; SINGLET OXYGEN;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL LINE; CELL PROTECTION; CHEMICAL REACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ACTIVITY; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED RADIATION; LUMINESCENCE; MITOCHONDRIAL RESPIRATION; NERVE CELL; NONHUMAN; RAT;

ANIMALS; ANTIPYRINE; CELL DEATH; CELL LINE; CELL-FREE SYSTEM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FREE RADICAL SCAVENGERS; MICROSCOPY, CONFOCAL; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; ROSE BENGAL; SINGLET OXYGEN; SPECTROMETRY, FLUORESCENCE;

RATTUS;

EID: 77952670768     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.03.017     Document Type: Article

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