Effect of isomalt as novel binding agent on compressibility of poorly compactable paracetamol evaluated by factorial design

Powder Technology

Volumn 201, Issue 2, 2010, Pages 123-129

  Sáska, Zs ^a   Dredan J ^a   Balogh, E ^a   Luhn, O ^b   Shafir, G ^a   Antal, I ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b BENEO Palatinit GmbH   (Germany)

Author keywords

Binder; Compaction; Compressibility; Factorial design; Isomalt; Wet granulation

Indexed keywords

BINDER PROPERTIES; BINDING AGENT; COMPRESSION FORCE; COMPRESSION PROCESS; DEPENDENT VARIABLES; DOSAGE FORMS; FACTORIAL DESIGN; FRICTION WORK; FULL FACTORIAL DESIGN; INDEPENDENT VARIABLES; ISOMALT; MODEL DRUGS; OPTIMAL COMPOSITION; PARACETAMOL; R VALUE; TABLETTING; WET GRANULATION;

BINDERS; COMPACTION; COMPRESSIBILITY; DESIGN; TENSILE STRENGTH;

GRANULATION;

ISOMALT; PARACETAMOL;

ARTICLE; CRYSTALLIZATION; DRUG DOSAGE FORM; DRUG GRANULATION; ELASTICITY; TABLET COMPRESSION; TABLET DISINTEGRATION; TABLET FRIABILITY; TABLET HARDNESS; TABLET MANUFACTURE; TABLET PROPERTY; TENSILE STRENGTH;

EID: 77952670407     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.03.009     Document Type: Article

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