Correlation between loose density and compactibility of granules prepared by various granulation methods

International Journal of Pharmaceutics

Volumn 216, Issue 1-2, 2001, Pages 159-164

  Murakami, Hideki ^a   Yoneyama, Takashi ^a   Nakajima, Kingo ^a   Kobayashi, Masao ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Compactibility; Compressibility; Loose density; Melt granulation method; Wet granulation method

Indexed keywords

LACTOSE; MACROGOL 6000;

ARTICLE; DENSITY; DRUG GRANULATION; INTERMETHOD COMPARISON; PARTICLE SIZE; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET POROSITY; TENSILE STRENGTH;

CHEMISTRY, PHARMACEUTICAL; LACTOSE;

EID: 0035937450     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00575-0     Document Type: Article

References (18)

1. Tablet strength, porosity, elasticity and solid state structure of tablets compressed at high loads
2. Melt granulation in Roto J high shear mixer
3. The tensile strength of lactose tablets
4. The preparation and properties of tablets containing indomethacin and polyethylene glycol 6000
5. The compressibility and compactibility of pharmaceutical powders
6. The compressibility and compactibility of pharmaceutical powders
7. Compression of lactose, glucose and mannitol granules
8. Change in porosity parameters of lactose, glucose and mannitol granules caused low compression force
9. The compactibillity of powder systems - A novel approach
10. The compressibility and compactibility of powder systems
11. Melting granulation by addition of polyethyleneglycol for stabilization of TAT-591-3
12. Influence of the granulating method on bulk properties and tablettability of a high dosage drug
13. Buoyancy and drug release patterns of floating minitablets containing piretanide and atenolol as model drugs
14. Melt granulation in a laboratory scale high sher mixer
15. Binder functionaly in tabletted systems
16. Preparation
17. Compression characteristics of granulated materials: IV. The effect of granule porosity on the fragmentation propensity and the compactibility of some granulations
18. Effect of binder on the relationship between bulk density and compactibility of lactose granulations