Population pharmacokinetics and pharmacodynamic considerations of amodiaquine and desethylamodiaquine in Kenyan adults with uncomplicated malaria receiving artesunate-amodiaquine combination therapy

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 6, 2010, Pages 2611-2617

  Jullien, Vincent ^a   Ogutu, Bernhards ^b   Juma, Elizabeth ^c   Carn, Gwenaelle ^d   Obonyo, Charles ^c   Kiechel, Jean René ^d  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c Medical Research Institute   (Kenya)

^d Drugs for Neglected Diseases Initiative   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; AMODIAQUINE PLUS ARTESUNATE; ARTESUNATE; DEETHYLAMODIAQUINE;

ADULT; ARTICLE; BODY WEIGHT; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG ABSORPTION; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TRANSFORMATION; FEMALE; HUMAN; KENYA; MAJOR CLINICAL STUDY; MALARIA; MALE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AMODIAQUINE; ANTIMALARIALS; ARTEMISININS; DRUG COMBINATIONS; FEMALE; HALF-LIFE; HUMANS; KENYA; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77952653142     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01496-09     Document Type: Article

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