Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: Studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 6, 2010, Pages 2549-2559

  Lemaire, Sandrine ^a   Kosowska Shick, Klaudia ^b   Appelbaum, Peter C ^b   Verween, Gunther ^c   Tulkens, Paul M ^a   Van Bambeke, Françoise ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c QUEEN ASTRID MILITARY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

LINEZOLID; OXAZOLIDINONE DERIVATIVE; RADEZOLID; RX 1741; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DRUG ACCUMULATION; ENDOTHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; KERATINOCYTE; LEGIONELLA PNEUMOPHILA; LISTERIA MONOCYTOGENES; LYSOSOME; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ACETAMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, BACTERIAL; HUMANS; LEGIONELLA PNEUMOPHILA; LISTERIA MONOCYTOGENES; MICROBIAL SENSITIVITY TESTS; OXAZOLIDINONES; PHAGOCYTES; RATS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 77952641580     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01724-09     Document Type: Article

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