Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): Studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines

Journal of Antimicrobial Chemotherapy

Volumn 64, Issue 5, 2009, Pages

  Lemaire, Sandrine ^a   Van Bambeke, Françoise ^a   Appelbaum, Peter C ^b   Tulkens, Paul M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINEZOLID; OXAZOLIDINONE DERIVATIVE; TOREZOLID; TR 700; UNCLASSIFIED DRUG; 3 (3 FLUORO 4 (6 (2 METHYL 2H TETRAZOL 5 YL)PYRIDIN 3 YL)PHENYL) 5 HYDROXYMETHYLOXAZOLIDIN 2 ONE; 3-(3-FLUORO-4-(6-(2-METHYL-2H-TETRAZOL-5-YL)PYRIDIN-3-YL)PHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE; ANTIINFECTIVE AGENT; TETRAZOLE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIOSTASIS; CELL INVASION; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG POTENCY; DRUG STRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INTRACELLULAR BACTERIUM; INTRACELLULAR KILLING; LEGIONELLA PNEUMOPHILA; LISTERIA MONOCYTOGENES; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS; BACTERIAL COUNT; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOSOL; DRUG EFFECT; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY;

ANTI-BACTERIAL AGENTS; CELL LINE; COLONY COUNT, MICROBIAL; CYTOSOL; ENDOTHELIAL CELLS; HUMANS; LEGIONELLA PNEUMOPHILA; LISTERIA MONOCYTOGENES; MACROPHAGES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXAZOLIDINONES; STAPHYLOCOCCUS AUREUS; TETRAZOLES;

EID: 73949088615     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkp267     Document Type: Article

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