Connexin 43 mediates the tangential to radial migratory switch in ventrally derived cortical interneurons

Journal of Neuroscience

Volumn 30, Issue 20, 2010, Pages 7072-7077

  Elias, Laura A B ^a   Turmaine, Mark ^b   Parnavelas, John G ^b   Kriegstein, Arnold R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 26; CONNEXIN 43; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; GAP JUNCTION; GENE INACTIVATION; GLIA; INTERNEURON; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RNA INTERFERENCE;

ANIMALS; CELL MOVEMENT; CEREBRAL CORTEX; CONNEXIN 43; CONNEXINS; ELECTROPORATION; EMBRYO, MAMMALIAN; FEMALE; GAP JUNCTIONS; GREEN FLUORESCENT PROTEINS; INTERNEURONS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NEURAL INHIBITION; NEUROGLIA; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; TIME FACTORS;

EID: 77952638131     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5728-09.2010     Document Type: Article

References (35)

1. Anderson SA, Eisenstat DD, Shi L, Rubenstein JL (1997) Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278:474-476. (Pubitemid 27454433)
2. Anderson SA, Marín O, Horn C, Jennings K, Rubenstein JL (2001) Distinct cortical migrations from the medial and lateral ganglionic eminences. Development 128:353-363. (Pubitemid 32184376)
3. Ang ES Jr, Haydar TF, Gluncic V, Rakic P (2003) Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex. J Neurosci 23:5805-5815. (Pubitemid 36807860)
4. Beahm DL, Oshima A, Gaietta GM, Hand GM, Smock AE, Zucker SN, Toloue MM, Chandrasekhar A, Nicholson BJ, Sosinsky GE (2006) Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel. J Biol Chem 281:7994-8009. (Pubitemid 43847417)
5. Cina C, Bechberger JF, Ozog MA, Naus CC (2007) Expression of connexins in embryonic mouse neocortical development. J Comp Neurol 504:298-313. (Pubitemid 350012216)
6. Cina C, Maass K, Theis M, Willecke K, Bechberger JF, Naus CC (2009) Involvement of the cytoplasmic C-terminal domain of connexin43 in neuronal migration. J Neurosci 29:2009-2021.
7. Edmunds SM, Parnavelas JG (1982) Retzius-Cajal cells: an ultrastructural study in the developing visual cortex of the rat. J Neurocytol 11:427-446. (Pubitemid 12114617)
8. Elias L, Kriegstein A (2007) Organotypic slice culture of E18 rat brains. J Vis Exp:235.
9. Elias LA, Kriegstein AR (2008) Gap junctions: multifaceted regulators of embryonic cortical development. Trends Neurosci 31:243-250.
10. Elias LA, Wang DD, Kriegstein AR (2007) Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448:901-907.
11. Fairén A, Cobas A, Fonseca M (1986) Times of generation of glutamic acid decarboxylase immunoreactive neurons in mouse somatosensory cortex. J Comp Neurol 251:67-83. (Pubitemid 16012189)
12. Friocourt G, Liu JS, Antypa M, Rakic S, Walsh CA, Parnavelas JG (2007) Both doublecortin and doublecortin-like kinase play a role in cortical interneuron migration. J Neurosci 27:3875-3883. (Pubitemid 46557665)
13. Fushiki S, Perez Velazquez JL, Zhang L, Bechberger JF, Carlen PL, Naus CC (2003) Changes in neuronal migration in neocortex of connexin43 null mutant mice. J Neuropathol Exp Neurol 62:304-314. (Pubitemid 36330681)
14. Giepmans BN (2004) Gap junctions and connexin-interacting proteins. Cardiovasc Res 62:233-245.
15. Giepmans BN, Moolenaar WH (1998) The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol 8:931-934.
16. Giepmans BN, Verlaan I, Hengeveld T, Janssen H, Calafat J, Falk MM, Moolenaar WH (2001) Gap junction protein connexin-43 interacts directly with microtubules. Curr Biol 11:1364-1368. (Pubitemid 32835878)
17. Harris AL (2007) Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol 94:120-143.
18. Lavdas AA, Grigoriou M, Pachnis V, Parnavelas JG (1999) The medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex. J Neurosci 19:7881-7888. (Pubitemid 30225786)
19. Lin JH, Takano T, Cotrina ML, Arcuino G, Kang J, Liu S, Gao Q, Jiang L, Li F, Lichtenberg-Frate H, Haubrich S, Willecke K, Goldman SA, Nedergaard M (2002) Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J Neurosci 22:4302-4311. (Pubitemid 37465645)
20. Lin R, Warn-Cramer BJ, Kurata WE, Lau AF (2001) v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication. J Cell Biol 154:815-827. (Pubitemid 34292962)
21. Malatesta P, Hartfuss E, Götz M (2000) Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development 127:5253-5263. (Pubitemid 32049182)
22. Malatesta P, Hack MA, Hartfuss E, Kettenmann H, Klinkert W, Kirchhoff F, Götz M (2003) Neuronal or glial progeny: regional differences in radial glia fate. Neuron 37:751-764. (Pubitemid 36288548)
23. Miller MW (1985) Cogeneration of retrogradely labeled corticocortical projection and GABA-immunoreactive local circuit neurons in cerebral cortex. Brain Res 355:187-192.
24. Nadarajah B, Parnavelas JG (2002) Modes of neuronal migration in the developing cerebral cortex. Nat Rev Neurosci 3:423-432. (Pubitemid 135711798)
25. Nadarajah B, Jones AM, Evans WH, Parnavelas JG (1997) Differential expression of connexins during neocortical development and neuronal circuit formation. J Neurosci 17:3096-3111. (Pubitemid 27175822)
26. Noctor SC, Flint AC, Weissman TA, Dammerman RS, Kriegstein AR (2001) Neurons derived from radial glial cells establish radial units in neocortex. Nature 409:714-720.
27. Noctor SC, Flint AC, Weissman TA, Wong WS, Clinton BK, Kriegstein AR (2002) Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia. J Neurosci 22:3161-3173.
28. Polleux F, Whitford KL, Dijkhuizen PA, Vitalis T, Ghosh A (2002) Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling. Development 129:3147-3160. (Pubitemid 34874289)
29. Poluch S, Juliano SL (2007) A normal radial glial scaffold is necessary for migration of interneurons during neocortical development. Glia 55:822-830. (Pubitemid 46787193)
30. Rakic P (1971) Guidance of neurons migrating to the fetal monkey neocortex. Brain Res 33:471-476.
31. Rakic P (1972) Mode of cell migration to the superficial layers of fetal monkey neocortex. J Comp Neurol 145:61-83.
32. Rakic P (1988) Specification of cerebral cortical areas. Science 241:170-176.
33. Rakić S, Yanagawa Y, Obata K, Faux C, Parnavelas JG, Nikolić M (2009) Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Cereb Cortex 19:1857-1869.
34. Tanaka D, Nakaya Y, Yanagawa Y, Obata K, Murakami F (2003) Multimodal tangential migration of neocortical GABAergic neurons independent of GPI-anchored proteins. Development 130:5803-5813. (Pubitemid 37540853)
35. Yokota Y, Gashghaei HT, Han C, Watson H, Campbell KJ, Anton ES (2007) Radial glial dependent and independent dynamics of interneuronal migration in the developing cerebral cortex. PLoS ONE 2:e794. (Pubitemid 351409135)