Correlation of cell strain in single osteocytes with intracellular calcium, but not intracellular nitric oxide, in response to fluid flow

Journal of Biomechanics

Volumn 43, Issue 8, 2010, Pages 1560-1564

  Rath, Amber L ^a,b   Bonewald, Lynda F ^c   Ling, Jian ^b   Jiang, Jean X ^d   Van Dyke, Mark E ^a   Nicolella, Daniel P ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b SOUTHWEST RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF DENTISTRY   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Calcium; Fluid flow; Osteocytes; Shear stress; Strain

Indexed keywords

BASAL LEVELS; BIOLOGICAL RESPONSE; BONE CELLS; CELL STRAINS; DIGITAL IMAGE CORRELATIONS; FLUID FLOW; FLUID FLOW RATES; FLUORESCENCE INTENSITIES; IN-CELL; INDIVIDUAL CELLS; INTRACELLULAR CALCIUM; INTRACELLULAR CALCIUM CONCENTRATION; LAMINAR FLUID FLOW; MECHANOSENSING; MECHANOSENSORS; OSTEOCYTES; SINGLE-CELL LEVEL; UP-REGULATION;

BONE; CALCIUM; CELLS; CYTOLOGY; FLUIDS; NITRIC OXIDE; SHEAR STRESS; STRAIN; STRENGTH OF MATERIALS;

FLOW OF FLUIDS;

CALCIUM; DIAMINORHODAMINE 4M ACETOXYMETHYL ESTER; FLUO 4 ACETOXYMETHYL ESTER; FLUORESCENT DYE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL STIMULATION; CELLULAR STRESS RESPONSE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOMETRY; DIGITAL IMAGING; FLUID FLOW; FLUORESCENCE ANALYSIS; LAMINAR FLOW; OSTEOCYTE; PRIORITY JOURNAL; SHEAR STRESS; STRESS STRAIN RELATIONSHIP; UPREGULATION;

ANIMALS; BODY FLUIDS; CALCIUM; CELL LINE; COMPUTER SIMULATION; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; NITRIC OXIDE; OSTEOCYTES; RATS; SHEAR STRENGTH; STATISTICS AS TOPIC; STRESS, MECHANICAL;

EID: 77952584430     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.01.030     Document Type: Article

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