메뉴 건너뛰기




Volumn 28, Issue 25, 2010, Pages 4145-4152

Soluble recombinant human metapneumovirus G protein is immunogenic but not protective

Author keywords

Glycoprotein; Metapneumovirus; Paramyxovirus; Vaccine

Indexed keywords

NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS GLYCOPROTEIN G;

EID: 77952582621     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.04.007     Document Type: Article
Times cited : (41)

References (44)
  • 1
    • 31044434930 scopus 로고    scopus 로고
    • The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience
    • Williams J.V., Wang C.K., Yang C.F., Tollefson S.J., House F.S., Heck J.M., et al. The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J Infect Dis 193 February (3) (2006) 387-395
    • (2006) J Infect Dis , vol.193 , Issue.February 3 , pp. 387-395
    • Williams, J.V.1    Wang, C.K.2    Yang, C.F.3    Tollefson, S.J.4    House, F.S.5    Heck, J.M.6
  • 2
    • 1642499234 scopus 로고    scopus 로고
    • Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children
    • Williams J.V., Harris P.A., Tollefson S.J., Halburnt-Rush L.L., Pingsterhaus J.M., Edwards K.M., et al. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med 350 January (5) (2004) 443-450
    • (2004) N Engl J Med , vol.350 , Issue.January 5 , pp. 443-450
    • Williams, J.V.1    Harris, P.A.2    Tollefson, S.J.3    Halburnt-Rush, L.L.4    Pingsterhaus, J.M.5    Edwards, K.M.6
  • 3
  • 4
    • 0034953901 scopus 로고    scopus 로고
    • A newly discovered human pneumovirus isolated from young children with respiratory tract disease
    • van den Hoogen B.G., de Jong J.C., Groen J., Kuiken T., de Groot R., Fouchier R.A., et al. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 7 June (6) (2001) 719-724
    • (2001) Nat Med , vol.7 , Issue.June 6 , pp. 719-724
    • van den Hoogen, B.G.1    de Jong, J.C.2    Groen, J.3    Kuiken, T.4    de Groot, R.5    Fouchier, R.A.6
  • 6
    • 0037711390 scopus 로고    scopus 로고
    • Children with respiratory disease associated with metapneumovirus in Hong Kong
    • Peiris J.S., Tang W.H., Chan K.H., Khong P.L., Guan Y., Lau Y.L., et al. Children with respiratory disease associated with metapneumovirus in Hong Kong. Emerg Infect Dis 9 June (6) (2003) 628-633
    • (2003) Emerg Infect Dis , vol.9 , Issue.June 6 , pp. 628-633
    • Peiris, J.S.1    Tang, W.H.2    Chan, K.H.3    Khong, P.L.4    Guan, Y.5    Lau, Y.L.6
  • 7
    • 1842588559 scopus 로고    scopus 로고
    • Human metapneumovirus infection among children hospitalized with acute respiratory illness
    • Mullins J.A., Erdman D.D., Weinberg G.A., Edwards K., Hall C.B., Walker F.J., et al. Human metapneumovirus infection among children hospitalized with acute respiratory illness. Emerg Infect Dis 10 April (4) (2004) 700-705
    • (2004) Emerg Infect Dis , vol.10 , Issue.April 4 , pp. 700-705
    • Mullins, J.A.1    Erdman, D.D.2    Weinberg, G.A.3    Edwards, K.4    Hall, C.B.5    Walker, F.J.6
  • 8
    • 33746327008 scopus 로고    scopus 로고
    • Human metapneumovirus and exacerbations of chronic obstructive pulmonary disease
    • Martinello R.A., Esper F., Weibel C., Ferguson D., Landry M.L., and Kahn J.S. Human metapneumovirus and exacerbations of chronic obstructive pulmonary disease. J Infect 53 October (4) (2006) 248-254
    • (2006) J Infect , vol.53 , Issue.October 4 , pp. 248-254
    • Martinello, R.A.1    Esper, F.2    Weibel, C.3    Ferguson, D.4    Landry, M.L.5    Kahn, J.S.6
  • 9
    • 0037333256 scopus 로고    scopus 로고
    • Human metapneumovirus infections in young and elderly adults
    • Falsey A.R., Erdman D., Anderson L.J., and Walsh E.E. Human metapneumovirus infections in young and elderly adults. J Infect Dis 187 March (5) (2003) 785-790
    • (2003) J Infect Dis , vol.187 , Issue.March 5 , pp. 785-790
    • Falsey, A.R.1    Erdman, D.2    Anderson, L.J.3    Walsh, E.E.4
  • 10
    • 2142708094 scopus 로고    scopus 로고
    • A 1-year experience with human metapneumovirus in children aged <5 years
    • Esper F., Martinello R.A., Boucher D., Weibel C., Ferguson D., Landry M.L., et al. A 1-year experience with human metapneumovirus in children aged <5 years. J Infect Dis 189 April (8) (2004) 1388-1396
    • (2004) J Infect Dis , vol.189 , Issue.April 8 , pp. 1388-1396
    • Esper, F.1    Martinello, R.A.2    Boucher, D.3    Weibel, C.4    Ferguson, D.5    Landry, M.L.6
  • 13
  • 14
    • 33645122915 scopus 로고    scopus 로고
    • Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients
    • Englund J.A., Boeckh M., Kuypers J., Nichols W.G., Hackman R.C., Morrow R.A., et al. Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients. Ann Intern Med 144 March (5) (2006) 344-349
    • (2006) Ann Intern Med , vol.144 , Issue.March 5 , pp. 344-349
    • Englund, J.A.1    Boeckh, M.2    Kuypers, J.3    Nichols, W.G.4    Hackman, R.C.5    Morrow, R.A.6
  • 15
    • 27844455579 scopus 로고    scopus 로고
    • Human metapneumovirus infection in lung transplant recipients: clinical presentation and epidemiology
    • Larcher C., Geltner C., Fischer H., Nachbaur D., Muller L.C., and Huemer H.P. Human metapneumovirus infection in lung transplant recipients: clinical presentation and epidemiology. J Heart Lung Transplant 24 11 (2005 Nov) 1891-1901
    • (2005) J Heart Lung Transplant , vol.24 , Issue.11 , pp. 1891-1901
    • Larcher, C.1    Geltner, C.2    Fischer, H.3    Nachbaur, D.4    Muller, L.C.5    Huemer, H.P.6
  • 16
    • 34247219202 scopus 로고    scopus 로고
    • An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility
    • Boivin G., De Serres G., Hamelin M.E., Cote S., Argouin M., Tremblay G., et al. An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility. Clin Infect Dis 44 May (9) (2007) 1152-1158
    • (2007) Clin Infect Dis , vol.44 , Issue.May 9 , pp. 1152-1158
    • Boivin, G.1    De Serres, G.2    Hamelin, M.E.3    Cote, S.4    Argouin, M.5    Tremblay, G.6
  • 17
    • 23244452361 scopus 로고    scopus 로고
    • Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease
    • Hamelin M.E., Cote S., Laforge J., Lampron N., Bourbeau J., Weiss K., et al. Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease. Clin Infect Dis 41 August (4) (2005) 498-502
    • (2005) Clin Infect Dis , vol.41 , Issue.August 4 , pp. 498-502
    • Hamelin, M.E.1    Cote, S.2    Laforge, J.3    Lampron, N.4    Bourbeau, J.5    Weiss, K.6
  • 18
    • 34247249922 scopus 로고    scopus 로고
    • Respiratory tract infection due to human metapneumovirus among elderly patients
    • van den Hoogen B.G. Respiratory tract infection due to human metapneumovirus among elderly patients. Clin Infect Dis 44 May (9) (2007) 1159-1160
    • (2007) Clin Infect Dis , vol.44 , Issue.May 9 , pp. 1159-1160
    • van den Hoogen, B.G.1
  • 19
    • 3042815029 scopus 로고    scopus 로고
    • Human metapneumovirus and chronic obstructive pulmonary disease
    • Vicente D., Montes M., Cilla G., and Perez-Trallero E. Human metapneumovirus and chronic obstructive pulmonary disease. Emerg Infect Dis 10 July (7) (2004) 1338-1339
    • (2004) Emerg Infect Dis , vol.10 , Issue.July 7 , pp. 1338-1339
    • Vicente, D.1    Montes, M.2    Cilla, G.3    Perez-Trallero, E.4
  • 20
    • 25444439052 scopus 로고    scopus 로고
    • Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults
    • Williams J.V., Crowe Jr. J.E., Enriquez R., Minton P., Peebles Jr. R.S., Hamilton R.G., et al. Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis 192 October (7) (2005) 1149-1153
    • (2005) J Infect Dis , vol.192 , Issue.October 7 , pp. 1149-1153
    • Williams, J.V.1    Crowe Jr., J.E.2    Enriquez, R.3    Minton, P.4    Peebles Jr., R.S.5    Hamilton, R.G.6
  • 21
    • 24644471867 scopus 로고    scopus 로고
    • A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections
    • Williams J.V., Martino R., Rabella N., Otegui M., Parody R., Heck J.M., et al. A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis 192 September (6) (2005) 1061-1065
    • (2005) J Infect Dis , vol.192 , Issue.September 6 , pp. 1061-1065
    • Williams, J.V.1    Martino, R.2    Rabella, N.3    Otegui, M.4    Parody, R.5    Heck, J.M.6
  • 22
    • 33846100643 scopus 로고    scopus 로고
    • Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats
    • Cseke G., Wright D.W., Tollefson S.J., Johnson J.E., Crowe Jr. J.E., and Williams J.V. Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol 81 January (2) (2007) 698-707
    • (2007) J Virol , vol.81 , Issue.January 2 , pp. 698-707
    • Cseke, G.1    Wright, D.W.2    Tollefson, S.J.3    Johnson, J.E.4    Crowe Jr., J.E.5    Williams, J.V.6
  • 23
    • 35048829250 scopus 로고    scopus 로고
    • Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains
    • Herfst S., de Graaf M., Schrauwen E.J., Ulbrandt N.D., Barnes A.S., Senthil K., et al. Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains. J Gen Virol 88 October (Pt 10) (2007) 2702-2709
    • (2007) J Gen Virol , vol.88 , Issue.October PART 10 , pp. 2702-2709
    • Herfst, S.1    de Graaf, M.2    Schrauwen, E.J.3    Ulbrandt, N.D.4    Barnes, A.S.5    Senthil, K.6
  • 24
    • 2942676473 scopus 로고    scopus 로고
    • The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness
    • Skiadopoulos M.H., Biacchesi S., Buchholz U.J., Riggs J.M., Surman S.R., Amaro-Carambot E., et al. The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness. J Virol 78 July (13) (2004) 6927-6937
    • (2004) J Virol , vol.78 , Issue.July 13 , pp. 6927-6937
    • Skiadopoulos, M.H.1    Biacchesi, S.2    Buchholz, U.J.3    Riggs, J.M.4    Surman, S.R.5    Amaro-Carambot, E.6
  • 25
    • 13544266576 scopus 로고    scopus 로고
    • A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys
    • Tang R.S., Mahmood K., Macphail M., Guzzetta J.M., Haller A.A., Liu H., et al. A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys. Vaccine 23 February (14) (2005) 1657-1667
    • (2005) Vaccine , vol.23 , Issue.February 14 , pp. 1657-1667
    • Tang, R.S.1    Mahmood, K.2    Macphail, M.3    Guzzetta, J.M.4    Haller, A.A.5    Liu, H.6
  • 26
    • 25144456514 scopus 로고    scopus 로고
    • Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates
    • Biacchesi S., Pham Q.N., Skiadopoulos M.H., Murphy B.R., Collins P.L., and Buchholz U.J. Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates. J Virol 79 October (19) (2005) 12608-12613
    • (2005) J Virol , vol.79 , Issue.October 19 , pp. 12608-12613
    • Biacchesi, S.1    Pham, Q.N.2    Skiadopoulos, M.H.3    Murphy, B.R.4    Collins, P.L.5    Buchholz, U.J.6
  • 27
    • 8644281996 scopus 로고    scopus 로고
    • Recombinant human Metapneumovirus lacking the small hydrophobic SH and/or attachment G glycoprotein: deletion of G yields a promising vaccine candidate
    • Biacchesi S., Skiadopoulos M.H., Yang L., Lamirande E.W., Tran K.C., Murphy B.R., et al. Recombinant human Metapneumovirus lacking the small hydrophobic SH and/or attachment G glycoprotein: deletion of G yields a promising vaccine candidate. J Virol 78 December (23) (2004) 12877-12887
    • (2004) J Virol , vol.78 , Issue.December 23 , pp. 12877-12887
    • Biacchesi, S.1    Skiadopoulos, M.H.2    Yang, L.3    Lamirande, E.W.4    Tran, K.C.5    Murphy, B.R.6
  • 28
    • 37049020254 scopus 로고    scopus 로고
    • Intracellular processing, glycosylation, and cell surface expression of human metapneumovirus attachment glycoprotein
    • Liu L., Bastien N., and Li Y. Intracellular processing, glycosylation, and cell surface expression of human metapneumovirus attachment glycoprotein. J Virol October (2007)
    • (2007) J Virol , Issue.October
    • Liu, L.1    Bastien, N.2    Li, Y.3
  • 30
    • 44949111358 scopus 로고    scopus 로고
    • Human metapneumovirus glycoprotein G inhibits innate immune responses
    • Bao X., Liu T., Shan Y., Li K., Garofalo R.P., and Casola A. Human metapneumovirus glycoprotein G inhibits innate immune responses. PLoS Pathog 4 5 (2008) e1000077
    • (2008) PLoS Pathog , vol.4 , Issue.5
    • Bao, X.1    Liu, T.2    Shan, Y.3    Li, K.4    Garofalo, R.P.5    Casola, A.6
  • 31
  • 32
    • 23844454493 scopus 로고    scopus 로고
    • The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity
    • Williams J.V., Tollefson S.J., Johnson J.E., and Crowe Jr. J.E. The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol 79 September (17) (2005) 10944-10951
    • (2005) J Virol , vol.79 , Issue.September 17 , pp. 10944-10951
    • Williams, J.V.1    Tollefson, S.J.2    Johnson, J.E.3    Crowe Jr., J.E.4
  • 34
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 May (1976) 248-254
    • (1976) Anal Biochem , vol.72 , Issue.May , pp. 248-254
    • Bradford, M.M.1
  • 35
    • 0018121934 scopus 로고
    • Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0. 5 to 50 microgram of protein
    • Spector T. Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0. 5 to 50 microgram of protein. Anal Biochem 86 May (1) (1978) 142-146
    • (1978) Anal Biochem , vol.86 , Issue.May 1 , pp. 142-146
    • Spector, T.1
  • 36
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 December (4) (2001) 402-408
    • (2001) Methods , vol.25 , Issue.December 4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 31944443421 scopus 로고    scopus 로고
    • Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity
    • Skiadopoulos M.H., Biacchesi S., Buchholz U.J., Amaro-Carambot E., Surman S.R., Collins P.L., et al. Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity. Virology 345 February (2) (2006) 492-501
    • (2006) Virology , vol.345 , Issue.February 2 , pp. 492-501
    • Skiadopoulos, M.H.1    Biacchesi, S.2    Buchholz, U.J.3    Amaro-Carambot, E.4    Surman, S.R.5    Collins, P.L.6
  • 38
    • 34547129591 scopus 로고    scopus 로고
    • A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo
    • Williams J.V., Chen Z., Cseke G., Wright D.W., Keefer C.J., Tollefson S.J., et al. A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J Virol 81 August (15) (2007) 8315-8324
    • (2007) J Virol , vol.81 , Issue.August 15 , pp. 8315-8324
    • Williams, J.V.1    Chen, Z.2    Cseke, G.3    Wright, D.W.4    Keefer, C.J.5    Tollefson, S.J.6
  • 39
    • 0037435937 scopus 로고    scopus 로고
    • Investigation of several selected adjuvants regarding their efficacy and side effects for the production of a vaccine for parakeets to prevent a disease caused by a paramyxovirus type 3
    • Beck I., Gerlach H., Burkhardt E., and Kaleta E.F. Investigation of several selected adjuvants regarding their efficacy and side effects for the production of a vaccine for parakeets to prevent a disease caused by a paramyxovirus type 3. Vaccine 21 February (9-10) (2003) 1006-1022
    • (2003) Vaccine , vol.21 , Issue.February 9-10 , pp. 1006-1022
    • Beck, I.1    Gerlach, H.2    Burkhardt, E.3    Kaleta, E.F.4
  • 40
    • 41149156364 scopus 로고    scopus 로고
    • Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge
    • Berhanu A., Wilson R.L., Kirkwood-Watts D.L., King D.S., Warren T.K., Lund S.A., et al. Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge. J Virol 82 April (7) (2008) 3517-3529
    • (2008) J Virol , vol.82 , Issue.April 7 , pp. 3517-3529
    • Berhanu, A.1    Wilson, R.L.2    Kirkwood-Watts, D.L.3    King, D.S.4    Warren, T.K.5    Lund, S.A.6
  • 41
    • 55549147517 scopus 로고    scopus 로고
    • An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats
    • Mok H., Tollefson S.J., Podsiad A.B., Shepherd B.E., Polosukhin V.V., Johnston R.E., et al. An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. J Virol 82 November (22) (2008) 11410-11418
    • (2008) J Virol , vol.82 , Issue.November 22 , pp. 11410-11418
    • Mok, H.1    Tollefson, S.J.2    Podsiad, A.B.3    Shepherd, B.E.4    Polosukhin, V.V.5    Johnston, R.E.6
  • 42
    • 77952584183 scopus 로고    scopus 로고
    • Positive natural selection in the evolution of human metapneumovirus attachment glycoprotein
    • Padhi A., and Verghese B. Positive natural selection in the evolution of human metapneumovirus attachment glycoprotein. Virus Res October (2007)
    • (2007) Virus Res , Issue.October
    • Padhi, A.1    Verghese, B.2
  • 43
    • 35148884680 scopus 로고    scopus 로고
    • Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus
    • Melendi G.A., Zavala F., Buchholz U.J., Boivin G., Collins P.L., Kleeberger S.R., et al. Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus. J Virol 81 October (20) (2007) 11461-11467
    • (2007) J Virol , vol.81 , Issue.October 20 , pp. 11461-11467
    • Melendi, G.A.1    Zavala, F.2    Buchholz, U.J.3    Boivin, G.4    Collins, P.L.5    Kleeberger, S.R.6
  • 44
    • 32444432815 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice
    • Herd K.A., Mahalingam S., Mackay I.M., Nissen M., Sloots T.P., and Tindle R.W. Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. J Virol 80 February (4) (2006) 2034-2044
    • (2006) J Virol , vol.80 , Issue.February 4 , pp. 2034-2044
    • Herd, K.A.1    Mahalingam, S.2    Mackay, I.M.3    Nissen, M.4    Sloots, T.P.5    Tindle, R.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.