A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo

Journal of Virology

Volumn 81, Issue 15, 2007, Pages 8315-8324

  Williams, John V ^a,b   Chen, Zhifeng ^c   Cseke, Gabriella ^a   Wright, David W ^a   Keefer, Christopher J ^a   Tollefson, Sharon J ^a   Hessell, Ann ^c   Podsiad, Amy ^a   Shepherd, Bryan E ^a   Sanna, Pietro Paolo ^c   Burton, Dennis R ^c   Crowe Jr , James E ^a,b   Williamson, R Anthony ^c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT HUMAN METAPNEUMOVIRUS FUSION PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIBODY LIBRARY; ARTICLE; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOFLUORESCENCE; IN VIVO STUDY; LOWER RESPIRATORY TRACT; METAPNEUMOVIRUS; NONHUMAN; PARAMYXOVIRUS; PHAGE DISPLAY; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE; TURBINATE; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; EPITOPES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INFANT; METAPNEUMOVIRUS; NEUTRALIZATION TESTS; PARAMYXOVIRIDAE INFECTIONS; PEPTIDE LIBRARY; RATS; RECOMBINANT PROTEINS; SIGMODONTINAE; VIRAL FUSION PROTEINS; VIRAL LOAD;

ANIMALIA; HUMAN METAPNEUMOVIRUS; PARAMYXOVIRIDAE; SIGMODON;

EID: 34547129591     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00106-07     Document Type: Article

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