An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats

Journal of Virology

Volumn 82, Issue 22, 2008, Pages 11410-11418

  Mok, Hoyin ^a   Tollefson, Sharon J ^a   Podsiad, Amy B ^a   Shepherd, Bryan E ^a   Polosukhin, Vasiliy V ^a   Johnston, Robert E ^c   Williams, John V ^a,b   Crowe Jr , James E ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HYBRID PROTEIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; MESSENGER RNA; METAPNEUMOVIRUS VACCINE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; COTTON RAT; DRUG EFFICACY; HISTOPATHOLOGY; HUMAN METAPNEUMOVIRUS; IMMUNOGENICITY; INFLAMMATION; LOWER RESPIRATORY TRACT; LUNG; MOLECULAR CLONING; MOUSE; MUCUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPLICON; RESPIRATORY TRACT MUCOSA; TURBINATE; UPPER RESPIRATORY TRACT; VACCINATION; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS; VIRAL RESPIRATORY TRACT INFECTION; VIRUS PARTICLE; VIRUS REPLICATION; WILD TYPE; ANIMAL; BLOOD; CELL LINE; DBA MOUSE; GENETICS; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; MACACA; METAPNEUMOVIRUS; MUCOSA; PATHOLOGY; RESPIRATORY SYSTEM; SERODIAGNOSIS; SIGMODONTINAE; VIROLOGY; VIRUS INFECTION;

ALPHAVIRUS; ANIMALIA; HUMAN METAPNEUMOVIRUS; MOROCCAN PEPPER VIRUS; MUS; PARAMYXOVIRIDAE; SIGMODON; VENEZUELAN EQUINE ENCEPHALITIS VIRUS;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; CELL LINE; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LUNG; MACACA MULATTA; METAPNEUMOVIRUS; MICE; MICE, INBRED DBA; MUCOUS MEMBRANE; NEUTRALIZATION TESTS; PARAMYXOVIRIDAE INFECTIONS; RATS; RESPIRATORY SYSTEM; SIGMODONTINAE; VIRAL STRUCTURAL PROTEINS; VIRAL VACCINES;

EID: 55549147517     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01688-08     Document Type: Article

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