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Volumn 87, Issue 6, 2010, Pages 706-713

A comprehensive hepatitis c viral kinetic model explaining cure

Author keywords

[No Author keywords available]

Indexed keywords

PEGINTERFERON ALPHA2A; RIBAVIRIN; VIRUS RNA;

EID: 77952581566     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2010.35     Document Type: Article
Times cited : (101)

References (40)
  • 1
    • 0003514452 scopus 로고    scopus 로고
    • Accessed 15 September 2008
    • World Health Organization. Hepatitis C http://www.who.int/mediacentre/ factsheets/fs164/en. Accessed 15 September 2008.
    • World Health Organization. Hepatitis C
  • 2
    • 0036829649 scopus 로고    scopus 로고
    • National Institutes of Health. National Institutes of Health Consensus Development Conference Statement: management of hepatitis C: 2002\June 10-12, 2002
    • National Institutes of Health. National Institutes of Health Consensus Development Conference Statement: management of hepatitis C: 2002\June 10-12, 2002. Hepatology 36, S3-S20 (2002).
    • (2002) Hepatology , vol.36
  • 3
    • 1842479859 scopus 로고    scopus 로고
    • American Association for the Study of Liver Diseases, Diagnosis, management, and treatment of hepatitis C
    • Strader, D.B., Wright, T., Thomas, D.L. & Seef, L.B.; American Association for the Study of Liver Diseases. Diagnosis, management, and treatment of hepatitis C. Hepatology 39, 1147-1171 (2004).
    • (2004) Hepatology , vol.39 , pp. 1147-1171
    • Strader, D.B.1    Wright, T.2    Thomas, D.L.3    Seef, L.B.4
  • 4
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried, M.W. et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N. Engl. J. Med. 347, 975-982 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , pp. 975-982
    • Fried, M.W.1
  • 5
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • PEGASYS International Study Group
    • Hadziyannis, S.J. et al.; PEGASYS International Study Group. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann. Intern. Med. 140, 346-355 (2004).
    • (2004) Ann. Intern. Med. , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1
  • 6
    • 0030587906 scopus 로고    scopus 로고
    • Hepatitis C virus genotypes in the United States: Epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group
    • Zein, N.N., Rakela, J., Krawitt, E.L., Reddy, K.R., Tominaga, T. & Persing, D.H. Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group. Ann. Intern. Med. 125, 634-639 (1996).
    • (1996) Ann. Intern. Med. , vol.125 , pp. 634-639
    • Zein, N.N.1    Rakela, J.2    Krawitt, E.L.3    Reddy, K.R.4    Tominaga, T.5    Persing, D.H.6
  • 7
    • 11144330097 scopus 로고    scopus 로고
    • Modelling how ribavirin improves interferon response rates in hepatitis C virus infection
    • Dixit, N.M., Layden-Almer, J.E., Layden, T.J. & Perelson, A.S. Modelling how ribavirin improves interferon response rates in hepatitis C virus infection. Nature 432, 922-924 (2004).
    • (2004) Nature , vol.432 , pp. 922-924
    • Dixit, N.M.1    Layden-Almer, J.E.2    Layden, T.J.3    Perelson, A.S.4
  • 8
  • 9
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral efcacy of interferon-alpha therapy
    • Neumann, A.U. et al. Hepatitis C viral dynamics in vivo and the antiviral efcacy of interferon-alpha therapy. Science 282, 103-107 (1998).
    • (1998) Science , vol.282 , pp. 103-107
    • Neumann, A.U.1
  • 10
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson, A.S., Neumann, A.U., Markowitz, M., Leonard, J.M. & Ho, D.D. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271, 1582-1586 (1996).
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 11
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodefciency virus type 1 infection
    • Wei, X. et al. Viral dynamics in human immunodefciency virus type 1 infection. Nature 373, 117-122 (1995).
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1
  • 12
    • 0348223940 scopus 로고    scopus 로고
    • Sustained response to interferon-ribavirin combination therapy predicted by a model of hepatitis C virus dynamics using both HCV RNA and alanine aminotransferase
    • Colombatto, P. et al. Sustained response to interferon-ribavirin combination therapy predicted by a model of hepatitis C virus dynamics using both HCV RNA and alanine aminotransferase. Antivir. Ther. (Lond.) 8, 519-530 (2003).
    • (2003) Antivir. Ther. (Lond.) , vol.8 , pp. 519-530
    • Colombatto, P.1
  • 13
    • 0034783406 scopus 로고    scopus 로고
    • The kinetics of hepatitis C virus infection
    • Zeuzem, S. The kinetics of hepatitis C virus infection. Clin. Liver Dis. 5, 917-930 (2001).
    • (2001) Clin. Liver Dis. , vol.5 , pp. 917-930
    • Zeuzem, S.1
  • 14
    • 0036211304 scopus 로고    scopus 로고
    • Viral kinetics of hepatitis C: New insights and remaining limitations
    • Layden, J.E. & Layden, T.J. Viral kinetics of hepatitis C: new insights and remaining limitations. Hepatology 35, 967-970 (2002).
    • (2002) Hepatology , vol.35 , pp. 967-970
    • Layden, J.E.1    Layden, T.J.2
  • 15
    • 33746239302 scopus 로고    scopus 로고
    • Viral kinetics in the treatment of chronic hepatitis C
    • Layden-Almer, J.E., Cotler, S.J. & Layden, T.J. Viral kinetics in the treatment of chronic hepatitis C. J. Viral Hepat. 13, 499-504 (2006).
    • (2006) J. Viral Hepat. , vol.13 , pp. 499-504
    • Layden-Almer, J.E.1    Cotler, S.J.2    Layden, T.J.3
  • 16
    • 34249896188 scopus 로고    scopus 로고
    • Modeling hepatitis C virus dynamics: Liver regeneration and critical drug efcacy
    • Dahari, H., Lo, A., Ribeiro, R.M. & Perelson, A.S. Modeling hepatitis C virus dynamics: liver regeneration and critical drug efcacy. J. Theor. Biol. 247, 371-381 (2007).
    • (2007) J. Theor. Biol. , vol.247 , pp. 371-381
    • Dahari, H.1    Lo, A.2    Ribeiro, R.M.3    Perelson, A.S.4
  • 17
    • 0036381110 scopus 로고    scopus 로고
    • HIV-1 infection and low steady state viral loads
    • Callaway, D.S. & Perelson, A.S. HIV-1 infection and low steady state viral loads. Bull. Math. Biol. 64, 29-64 (2002).
    • (2002) Bull. Math. Biol. , vol.64 , pp. 29-64
    • Callaway, D.S.1    Perelson, A.S.2
  • 18
    • 0037962332 scopus 로고    scopus 로고
    • Liver regeneration and surgical outcome in donors of right-lobe liver grafts
    • Pomfret, E.A. et al. Liver regeneration and surgical outcome in donors of right-lobe liver grafts. Transplantation 76, 5-10 (2003).
    • (2003) Transplantation , vol.76 , pp. 5-10
    • Pomfret, E.A.1
  • 19
    • 0033914625 scopus 로고    scopus 로고
    • Diferences in viral dynamics between genotypes 1 and 2 of hepatitis C virus
    • Neumann, A.U. et al. Diferences in viral dynamics between genotypes 1 and 2 of hepatitis C virus. J. Infect. Dis. 182, 28-35 (2000).
    • (2000) J. Infect. Dis. , vol.182 , pp. 28-35
    • Neumann, A.U.1
  • 20
    • 77952586239 scopus 로고    scopus 로고
    • US Food and Drug Administration
    • US Food and Drug Administration. Label information for Pegasys http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088679.pdf.
    • Label Information for Pegasys
  • 21
    • 77952583770 scopus 로고    scopus 로고
    • US Food and Drug Administration
    • US Food and Drug Administration. Label information for Copegus http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088576.pdf.
    • Label Information for Copegus
  • 22
    • 33750740728 scopus 로고    scopus 로고
    • Extension of the SAEM algorithm to left-censored data in nonlinear mixed-efects model: Application to HIV dynamics model
    • Samson, A., Lavielle, M. & Mentré, F. Extension of the SAEM algorithm to left-censored data in nonlinear mixed-efects model: Application to HIV dynamics model. Comput. Statist. Data Anal. 51, 1562-1574 (2006).
    • (2006) Comput. Statist. Data Anal. , vol.51 , pp. 1562-1574
    • Samson, A.1    Lavielle, M.2    Mentré, F.3
  • 24
    • 43949124553 scopus 로고    scopus 로고
    • Clearance of hepatitis C virus RNA from the peripheral blood mononuclear cells of blood donors who spontaneously or therapeutically control their plasma viremia
    • Bernardin, F., Tobler, L., Walsh, I., Williams, J.D., Busch, M. & Delwart, E. Clearance of hepatitis C virus RNA from the peripheral blood mononuclear cells of blood donors who spontaneously or therapeutically control their plasma viremia. Hepatology 47, 1446-1452 (2008).
    • (2008) Hepatology , vol.47 , pp. 1446-1452
    • Bernardin, F.1    Tobler, L.2    Walsh, I.3    Williams, J.D.4    Busch, M.5    Delwart, E.6
  • 25
    • 23344441748 scopus 로고    scopus 로고
    • Mathematical models of immune efector responses to viral infections: Virus control versus the development of pathology
    • Wodarz, D. Mathematical models of immune efector responses to viral infections: virus control versus the development of pathology. J. Comp. Appl. Math. 184, 301-319 (2005).
    • (2005) J. Comp. Appl. Math. , vol.184 , pp. 301-319
    • Wodarz, D.1
  • 26
    • 30044432484 scopus 로고    scopus 로고
    • American Gastroenterological Association technical review on the management of hepatitis C
    • quiz 214
    • Dienstag, J.L. & McHutchison, J.G. American Gastroenterological Association technical review on the management of hepatitis C. Gastroenterology 130, 231-64; quiz 214 (2006).
    • (2006) Gastroenterology , vol.130 , pp. 231-64
    • Dienstag, J.L.1    McHutchison, J.G.2
  • 27
    • 35948944562 scopus 로고    scopus 로고
    • The SAEM algorithm for group comparison tests in longitudinal data analysis based on non-linear mixed-efects model
    • Samson, A., Lavielle, M. & Mentré, F. The SAEM algorithm for group comparison tests in longitudinal data analysis based on non-linear mixed-efects model. Stat. Med. 26, 4860-4875 (2007).
    • (2007) Stat. Med. , vol.26 , pp. 4860-4875
    • Samson, A.1    Lavielle, M.2    Mentré, F.3
  • 28
    • 0034619980 scopus 로고    scopus 로고
    • Peginterferon α-2a in patients with chronic hepatitis C and cirrhosis
    • Heathcote, E.J. et al. Peginterferon α-2a in patients with chronic hepatitis C and cirrhosis. N. Engl. J. Med. 343, 1673-1680 (2000).
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1673-1680
    • Heathcote, E.J.1
  • 29
    • 77952585278 scopus 로고    scopus 로고
    • Peginterferon α-2a in patients with chronic hepatitis C
    • Zeuzem, S. et al. Peginterferon α-2a in patients with chronic hepatitis C. N. Engl. J. Med. 357, 124-134 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 124-134
    • Zeuzem, S.1
  • 30
    • 17744389383 scopus 로고    scopus 로고
    • Efcacy and safety of pegylated (40-kd) interferon alpha-2a compared with interferon alpha-2a in noncirrhotic patients with chronic hepatitis C
    • Reddy, K.R. et al. Efcacy and safety of pegylated (40-kd) interferon alpha-2a compared with interferon alpha-2a in noncirrhotic patients with chronic hepatitis C. Hepatology 33, 433-438 (2001).
    • (2001) Hepatology , vol.33 , pp. 433-438
    • Reddy, K.R.1
  • 31
    • 3843139484 scopus 로고    scopus 로고
    • Efcacy and safety of two-dose regimens of peginterferon alpha-2a compared with interferon alpha-2a in chronic hepatitis C: A multicenter, randomized controlled trial
    • PEGASYS International Study Group
    • Pockros, P.J. et al.; PEGASYS International Study Group. Efcacy and safety of two-dose regimens of peginterferon alpha-2a compared with interferon alpha-2a in chronic hepatitis C: a multicenter, randomized controlled trial. Am. J. Gastroenterol. 99, 1298-1305 (2004).
    • (2004) Am. J. Gastroenterol. , vol.99 , pp. 1298-1305
    • Pockros, P.J.1
  • 32
    • 0034461502 scopus 로고    scopus 로고
    • Improved version 2.0 qualitative and quantitative AMPLICOR reverse transcription-PCR tests for hepatitis C virus RNA: Calibration to international units, enhanced genotype reactivity, and performance characteristics
    • Lee, S.C. et al. Improved version 2.0 qualitative and quantitative AMPLICOR reverse transcription-PCR tests for hepatitis C virus RNA: calibration to international units, enhanced genotype reactivity, and performance characteristics. J. Clin. Microbiol. 38, 4171-4179 (2000).
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 4171-4179
    • Lee, S.C.1
  • 33
    • 33750987680 scopus 로고    scopus 로고
    • Predicting sustained virological response and anaemia in chronic hepatitis C patients treated with peginterferon α-2a (40KD) plus ribavirin
    • Snoeck, E., Wade, J.R., Duf, F., Lamb, M. & Jorga, K. Predicting sustained virological response and anaemia in chronic hepatitis C patients treated with peginterferon α-2a (40KD) plus ribavirin. Br. J. Clin. Pharmacol. 62, 699-709 (2006).
    • (2006) Br. J. Clin. Pharmacol. , vol.62 , pp. 699-709
    • Snoeck, E.1    Wade, J.R.2    Duf, F.3    Lamb, M.4    Jorga, K.5
  • 37
    • 0033243858 scopus 로고    scopus 로고
    • Covergence of a stochastic approximation version of the em algorithm
    • Delyon, B., Lavielle, M. & Moulines, E. Covergence of a stochastic approximation version of the EM algorithm. Ann. Statist. 27, 94-128 (1999).
    • (1999) Ann. Statist. , vol.27 , pp. 94-128
    • Delyon, B.1    Lavielle, M.2    Moulines, E.3
  • 38
    • 19044400906 scopus 로고    scopus 로고
    • Maximum likelihood estimation in nonlinear mixed efects models
    • Kuhn, E. & Laveille, M. Maximum likelihood estimation in nonlinear mixed efects models. Comput. Statist. Data Anal. 1020-1038 (2005).
    • (2005) Comput. Statist. Data Anal. , pp. 1020-1038
    • Kuhn, E.1    Laveille, M.2
  • 39
    • 84970866422 scopus 로고
    • Diagnostic tests. 1: Sensitivity and specifcity
    • Altman, D.G. & Bland, J.M. Diagnostic tests. 1: Sensitivity and specifcity. BMJ 308, 1552 (1994).
    • (1994) BMJ , vol.308 , pp. 1552
    • Altman, D.G.1    Bland, J.M.2


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