Placental restriction increases adipose leptin gene expression and plasma leptin and alters their relationship to feeding activity in the young lamb

Pediatric Research

Volumn 67, Issue 6, 2010, Pages 603-608

  De Blasio, Miles J ^a   Blache, Dominique ^b   Gatford, Kathryn L ^a   Robinson, Jeffrey S ^a   Owens, Julie A ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; BODY SIZE; CONTROLLED STUDY; FEEDING BEHAVIOR; FEMALE; GENE EXPRESSION; HORMONE BLOOD LEVEL; LAMB; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PLACENTA; PRIORITY JOURNAL; SUCKLING;

ADIPOSE TISSUE; ADIPOSITY; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; BIRTH WEIGHT; BLOOD GLUCOSE; DISEASE MODELS, ANIMAL; FATTY ACIDS, NONESTERIFIED; FEEDING BEHAVIOR; FEMALE; FETAL GROWTH RETARDATION; HYPERPHAGIA; INSULIN; LACTATION; LEPTIN; MALE; PLACENTAL INSUFFICIENCY; PREGNANCY; RECEPTORS, LEPTIN; SHEEP; UP-REGULATION;

EID: 77952550728     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e3181dbc471     Document Type: Article

References (42)

1. Rogers I; EURO-BLCS Study Group 2003 The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life. Int J Obes Relat Metab Disord 27:755-777
2. Ong KK, Ahmed ML, Emmett PM, Preece MA, Dunger DB 2000 Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. BMJ 320:967-971
3. Friedman JM, Halaas JL 1998 Leptin and the regulation of body weight in mammals. Nature 395:763-770
4. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM 1995 Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161
5. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF 1996 Serum immunore-active-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295
6. Huang L, Li C 2000 Leptin: a multifunctional hormone. Cell Res 10:81-92
7. Phillips DI, Fall CH, Cooper C, Norman RJ, Robinson JS, Owens PC 1999 Size at birth and plasma leptin concentrations in adult life. Int J Obes Relat Metab Disord 23:1025-1029
8. Bouret SG, Gorski JN, Patterson CM, Chen S, Levin BE, Simerly RB 2008 Hypothalamic neural projections are permanently disrupted in diet-induced obese rats. Cell Metab 7:179-185
9. Bouret SG, Simerly RB 2006 Developmental programming of hypothalamic feeding circuits. Clin Genet 70:295-301
10. Cianfarani S, Germani D, Branca F 1999 Low birthweight and adult insulin resistance: the "catch-up growth" hypothesis. ch Dis Child Fetal Neonatal Ed 81:F71-F73
11. Yura S, Itoh H, Sagawa N, Yamamoto H, Masuzaki H, Nakao K, Kawamura M, Takemura M, Kakui K, Ogawa Y, Fujii S 2005 Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab 1:371-378
12. Vickers MH, Breier BH, Cutfield WS, Hofman PL, Gluckman PD 2000 Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hyperca-loric nutrition. Am J Physiol Endocrinol Metab 279:E83-E87
13. Yuen BS, Owens PC, McFarlane JR, Symonds ME, Edwards LJ, Kauter KG, McMillen IC 2002 Circulating leptin concentrations are positively related to leptin messenger rna expression in the adipose tissue of fetal sheep in the pregnant ewe fed at or below maintenance energy requirements during late gestation. Biol Reprod 67:911-916
14. Husted SM, Nielsen MO, Tygesen MP, Kiani A, Blache D, Ingvartsen KL 2007 Programming of intermediate metabolism in young lambs affected by late gestational maternal undernourishment. Am J Physiol Endocrinol Metab 293:E548-E557
15. Greenwood PL, Hunt AS, Hermanson JW, Bell AW 1998 Effects of birth weight and postnatal nutrition on neonatal sheep: I. Body growth and composition, and some aspects of energetic efficiency. J Anim Sci 76:2354-2367
16. Ehrhardt RA, Greenwood PL, Bell AW, Boisclair YR 2003 Plasma leptin is regulated predominantly by nutrition in preruminant lambs. J Nutr 133:4196-4201
17. Pardi G, Marconi AM, Cetin I 2002 Placental-fetal interrelationship in IUGR fetuses-a review. Placenta 23:S136-S141
18. De Blasio MJ, Gatford KL, Robinson JS, Owens JA 2007 Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity and adiposity in the young lamb. Am J Physiol Regul Integr Comp Physiol 292:R875-R886
19. Robinson JS, Kingston EJ, Jones CT, Thornburn GD 1979 Studies on experimental growth retardation in sheep. The effect of removal of endometrial caruncles on fetal size and metabolism. J Dev Physiol 1:379-398
20. Owens JA, Falconer J, Robinson JS 1987 Effect of restriction of placental growth on oxygen delivery to and consumption by the pregnant uterus and fetus. J Dev Physiol 9:137-150
21. De Blasio MJ, Gatford KL, McMillen IC, Robinson JS, Owens JA 2007 Placental restriction of fetal growth increases insulin action, growth and adiposity in the young lamb. Endocrinology 148:1350-1358
22. De Blasio MJ, Gatford KL, Robinson JS, Owens JA 2006 Placental restriction alters circulating thyroid hormone in the young lamb postnatally. Am J Physiol Regul Integr Comp Physiol 291:R1016-R1024
23. Blache D, Tellam RL, Chagas LM, Blackberry MA, Vercoe PE, Martin GB 2000 Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep. J Endocrinol 165:625-637
24. Gatford KL, Mohammad SN, Harland ML, De Blasio MJ, Fowden AL, Robinson JS, Owens JA 2008 Impaired {beta}-cell function and inadequate compensatory increases in {beta}-cell mass following intrauterine growth restriction in sheep. Endocrinology 149:5118-5127
25. Irving-Rodgers HF, Harland ML, Sullivan TR, Rodgers RJ 2009 Studies of granu-losa cell maturation in dominant and subordinate bovine follicles: novel extracellular matrix focimatrix is co-ordinately regulated with cholesterol side-chain cleavage CYP11A1. Reproduction 137:825-834
26. Jaquet D, Leger J, Tabone MD, Czernichow P, Levy-Marchal C 1999 High serum leptin concentrations during catch-up growth of children born with intrauterine growth retardation. J Clin Endocrinol Metab 84:1949-1953
27. McFadin EL, Morrison CD, Buff PR, Whitley NC, Keisler DH 2002 Leptin concentrations in periparturient ewes and their subsequent offspring. J Anim Sci 80:738-743
28. Blum WF, Englaro P, Hanitsch S, Juul A, Hertel NT, Muller J, Skakkebak NE, Heiman ML, Birkett M, Attanasio AM, Kiess W, Rascher W 1997 Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone. J Clin Endocrinol Metab 82:2904-2910
29. Duffield JA, Vuocolo T, Tellam R, Yuen BS, Muhlhausler BS, McMillen IC 2008 Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep. Am J Physiol Regul Integr Comp Physiol 294:R1413-R1419
30. Steinberger J, Steffen L, Jacobs DR Jr, Moran A, Hong C, Sinaiko AR 2003 Relation of Leptin to Insulin Resistance Syndrome in Children. Obes Res 11:1124-1130
31. Haffner SM, Miettinen H, Mykkanen L, Karhapaa P, Rainwater DL, Laakso M 1997 Leptin concentrations and insulin sensitivity in normoglycemic men. Int J Obes Relat Metab Disord 21:393-399 (Pubitemid 27190192)
32. Boden G, Chen X, Kolaczynski JW, Polansky M 1997 Effects of Prolonged Hyperinsulinemia on Serum Leptin in Normal Human Subjects. J Clin Invest 100:1107-1113
33. Segal KR, Landt M, Klein S 1996 Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes 45:988-991
34. McMillen IC, Edwards LJ, Duffield J, Muhlhausler BS 2006 Regulation of leptin synthesis and secretion before birth: implications for the early programming of adult obesity. Reproduction 131:415-427
35. Grove KL, Smith MS 2003 Ontogeny of the hypothalamic neuropeptide Y system. Physiol Behav 79:47-63
36. Koutcherov Y, Mai JK, Paxinos G 2003 Hypothalamus of the human fetus. J Chem Neuroanat 26:253-270
37. Warnes KE, Morris MJ, Symonds ME, Phillips ID, Clarke IJ, Owens JA, McMillen IC 1998 Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus. J Neuroendocrinol 10:51-57
38. Grayson BE, Allen SE, Billes SK, Williams SM, Smith MS, Grove KL 2006 Prenatal development of hypothalamic neuropeptide systems in the nonhuman primate. Neuroscience 143:975-986
39. Grove KL, Allen S, Grayson BE, Smith MS 2003 Postnatal development of the hypothalamic neuropeptide Y system. Neuroscience 116:393-406
40. Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D Jr 1992 Insulin in the brain: a hormonal regulator of energy balance. Endocr Rev 13:387-414
41. O'Dowd R, Kent JC, Moseley JM, Wlodek ME 2008 Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth. Am J Physiol Regul Integr Comp Physiol 294:R539-R548
42. Delahaye F, Breton C, Risold P, Enache M, Dutriez-Casteloot I, Laborie C, Lesage J, Vieau D 2008 Maternal Perinatal Undernutrition Drastically Reduces Postnatal Leptin Surge and Affects the Development of Arcuate Nucleus Proopiomelanocortin Neurons in Neonatal Male Rat Pups. Endocrinology 149:470-475