메뉴 건너뛰기




Volumn 31, Issue 6, 2010, Pages 506-511

Transplacental Transfer and Biotransformation of Genistein in Human Placenta

Author keywords

Endocrine disruptors; Genistein; Genistein glucuronide; Phytoestrogens; Placental perfusion; Placental transfer

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GENISTEIN; GLUCURONIDE; PHENAZONE; SULFATE;

EID: 77952549105     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2010.03.007     Document Type: Article
Times cited : (39)

References (50)
  • 1
    • 0028822138 scopus 로고
    • Cellular and molecular effects of developmental exposure to diethylstilbestrol: implications for other environmental estrogens
    • Newbold R. Cellular and molecular effects of developmental exposure to diethylstilbestrol: implications for other environmental estrogens. Environ Health Perspect 103 Suppl. 7 (1995) 83-87
    • (1995) Environ Health Perspect , vol.103 , Issue.SUPPL. 7 , pp. 83-87
    • Newbold, R.1
  • 2
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn T., vom Saal F.S., and Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101 5 (1993) 378-384
    • (1993) Environ Health Perspect , vol.101 , Issue.5 , pp. 378-384
    • Colborn, T.1    vom Saal, F.S.2    Soto, A.M.3
  • 3
    • 0031973887 scopus 로고    scopus 로고
    • A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior
    • vom Saal F.S., Cooke P.S., Buchanan D.L., Palanza P., Thayer K.A., Nagel S.C., et al. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol Ind Health 14 1-2 (1998) 239-260
    • (1998) Toxicol Ind Health , vol.14 , Issue.1-2 , pp. 239-260
    • vom Saal, F.S.1    Cooke, P.S.2    Buchanan, D.L.3    Palanza, P.4    Thayer, K.A.5    Nagel, S.C.6
  • 5
    • 0036001270 scopus 로고    scopus 로고
    • Purified phytoestrogens in postmenopausal bone health: is there a role for genistein?
    • Albertazzi P. Purified phytoestrogens in postmenopausal bone health: is there a role for genistein?. Climacteric 5 2 (2002) 190-196
    • (2002) Climacteric , vol.5 , Issue.2 , pp. 190-196
    • Albertazzi, P.1
  • 6
    • 52649144703 scopus 로고    scopus 로고
    • The effects of soy isoflavones on obesity
    • Orgaard A., and Jensen L. The effects of soy isoflavones on obesity. Exp Biol Med (Maywood) 233 9 (2008) 1066-1080
    • (2008) Exp Biol Med (Maywood) , vol.233 , Issue.9 , pp. 1066-1080
    • Orgaard, A.1    Jensen, L.2
  • 7
    • 34548642951 scopus 로고    scopus 로고
    • Genistein genotoxicity: critical considerations of in vitro exposure dose
    • Klein C.B., and King A.A. Genistein genotoxicity: critical considerations of in vitro exposure dose. Toxicol Appl Pharmacol 224 1 (2007) 1-11
    • (2007) Toxicol Appl Pharmacol , vol.224 , Issue.1 , pp. 1-11
    • Klein, C.B.1    King, A.A.2
  • 8
    • 0013879912 scopus 로고
    • The interaction in the immature mouse of potent oestrogens with coumestrol, genistein and other utero-vaginotrophic compounds of low potency
    • Folman Y., and Pope G.S. The interaction in the immature mouse of potent oestrogens with coumestrol, genistein and other utero-vaginotrophic compounds of low potency. J Endocrinol 34 2 (1966) 215-225
    • (1966) J Endocrinol , vol.34 , Issue.2 , pp. 215-225
    • Folman, Y.1    Pope, G.S.2
  • 9
  • 10
    • 43249085452 scopus 로고    scopus 로고
    • The role of early life genistein exposures in modifying breast cancer risk
    • Warri A., Saarinen N.M., Makela S., and Hilakivi-Clarke L. The role of early life genistein exposures in modifying breast cancer risk. Br J Cancer 98 9 (2008) 1485-1493
    • (2008) Br J Cancer , vol.98 , Issue.9 , pp. 1485-1493
    • Warri, A.1    Saarinen, N.M.2    Makela, S.3    Hilakivi-Clarke, L.4
  • 11
    • 0035037554 scopus 로고    scopus 로고
    • Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats
    • Doerge D.R., Churchwell M.I., Chang H.C., Newbold R.R., and Delclos K.B. Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats. Reprod Toxicol 15 2 (2001) 105-110
    • (2001) Reprod Toxicol , vol.15 , Issue.2 , pp. 105-110
    • Doerge, D.R.1    Churchwell, M.I.2    Chang, H.C.3    Newbold, R.R.4    Delclos, K.B.5
  • 12
    • 33144467452 scopus 로고    scopus 로고
    • Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration
    • Soucy N.V., Parkinson H.D., Sochaski M.A., and Borghoff S.J. Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration. Toxicol Sci 90 1 (2006) 230-240
    • (2006) Toxicol Sci , vol.90 , Issue.1 , pp. 230-240
    • Soucy, N.V.1    Parkinson, H.D.2    Sochaski, M.A.3    Borghoff, S.J.4
  • 13
    • 0037376958 scopus 로고    scopus 로고
    • Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats
    • Wisniewski A.B., Klein S.L., Lakshmanan Y., and Gearhart J.P. Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats. J Urol 169 4 (2003) 1582-1586
    • (2003) J Urol , vol.169 , Issue.4 , pp. 1582-1586
    • Wisniewski, A.B.1    Klein, S.L.2    Lakshmanan, Y.3    Gearhart, J.P.4
  • 14
    • 0035360280 scopus 로고    scopus 로고
    • Uterine adenocarcinoma in mice treated neonatally with genistein
    • Newbold R.R., Banks E.P., Bullock B., and Jefferson W.N. Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61 11 (2001) 4325-4328
    • (2001) Cancer Res , vol.61 , Issue.11 , pp. 4325-4328
    • Newbold, R.R.1    Banks, E.P.2    Bullock, B.3    Jefferson, W.N.4
  • 15
    • 34547493433 scopus 로고    scopus 로고
    • Disruption of the developing female reproductive system by phytoestrogens: genistein as an example
    • Jefferson W.N., Padilla-Banks E., and Newbold R.R. Disruption of the developing female reproductive system by phytoestrogens: genistein as an example. Mol Nutr Food Res 51 7 (2007) 832-844
    • (2007) Mol Nutr Food Res , vol.51 , Issue.7 , pp. 832-844
    • Jefferson, W.N.1    Padilla-Banks, E.2    Newbold, R.R.3
  • 16
    • 34247375238 scopus 로고    scopus 로고
    • Disruption of the female reproductive system by the phytoestrogen genistein
    • Jefferson W.N., Padilla-Banks E., and Newbold R.R. Disruption of the female reproductive system by the phytoestrogen genistein. Reprod Toxicol 23 3 (2007) 308-316
    • (2007) Reprod Toxicol , vol.23 , Issue.3 , pp. 308-316
    • Jefferson, W.N.1    Padilla-Banks, E.2    Newbold, R.R.3
  • 17
    • 70349983562 scopus 로고    scopus 로고
    • Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague-Dawley rats
    • Latendresse J.R., Bucci T.J., Olson G., Mellick P., Weis C.C., Thorn B., et al. Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague-Dawley rats. Reprod Toxicol 28 3 (2009) 342-353
    • (2009) Reprod Toxicol , vol.28 , Issue.3 , pp. 342-353
    • Latendresse, J.R.1    Bucci, T.J.2    Olson, G.3    Mellick, P.4    Weis, C.C.5    Thorn, B.6
  • 18
    • 60749137152 scopus 로고    scopus 로고
    • Effects of phytoestrogens genistein and daidzein on progesterone and estrogen (estradiol) production of human term trophoblast cells in vitro
    • Richter D.U., Mylonas I., Toth B., Scholz C., Briese V., Friese K., et al. Effects of phytoestrogens genistein and daidzein on progesterone and estrogen (estradiol) production of human term trophoblast cells in vitro. Gynecol Endocrinol 25 1 (2009) 32-38
    • (2009) Gynecol Endocrinol , vol.25 , Issue.1 , pp. 32-38
    • Richter, D.U.1    Mylonas, I.2    Toth, B.3    Scholz, C.4    Briese, V.5    Friese, K.6
  • 19
    • 27744472489 scopus 로고    scopus 로고
    • Effects of phytoestrogens genistein and daidzein on production of human chorionic gonadotropin in term trophoblast cells in vitro
    • Jeschke U., Briese V., Richter D.U., Bruer G., Plessow D., Waldschlager J., et al. Effects of phytoestrogens genistein and daidzein on production of human chorionic gonadotropin in term trophoblast cells in vitro. Gynecol Endocrinol 21 3 (2005) 180-184
    • (2005) Gynecol Endocrinol , vol.21 , Issue.3 , pp. 180-184
    • Jeschke, U.1    Briese, V.2    Richter, D.U.3    Bruer, G.4    Plessow, D.5    Waldschlager, J.6
  • 20
    • 0033973630 scopus 로고    scopus 로고
    • A maternal vegetarian diet in pregnancy is associated with hypospadias. The ALSPAC Study Team. Avon longitudinal study of pregnancy and childhood
    • North K., and Golding J. A maternal vegetarian diet in pregnancy is associated with hypospadias. The ALSPAC Study Team. Avon longitudinal study of pregnancy and childhood. BJU Int 85 1 (2000) 107-113
    • (2000) BJU Int , vol.85 , Issue.1 , pp. 107-113
    • North, K.1    Golding, J.2
  • 21
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: bioavailability, metabolic effects, and safety
    • Ross J.A., and Kasum C.M. Dietary flavonoids: bioavailability, metabolic effects, and safety. Annu Rev Nutr 22 (2002) 19-34
    • (2002) Annu Rev Nutr , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 22
    • 0032980823 scopus 로고    scopus 로고
    • Maternal and neonatal phytoestrogens in Japanese women during birth
    • Adlercreutz H., Yamada T., Wahala K., and Watanabe S. Maternal and neonatal phytoestrogens in Japanese women during birth. Am J Obstet Gynecol 180 3 Pt 1 (1999) 737-743
    • (1999) Am J Obstet Gynecol , vol.180 , Issue.3 PART 1 , pp. 737-743
    • Adlercreutz, H.1    Yamada, T.2    Wahala, K.3    Watanabe, S.4
  • 23
    • 0037187358 scopus 로고    scopus 로고
    • Detection of phytoestrogens in samples of second trimester human amniotic fluid
    • Foster W.G., Chan S., Platt L., and Hughes Jr. C.L. Detection of phytoestrogens in samples of second trimester human amniotic fluid. Toxicol Lett 129 3 (2002) 199-205
    • (2002) Toxicol Lett , vol.129 , Issue.3 , pp. 199-205
    • Foster, W.G.1    Chan, S.2    Platt, L.3    Hughes Jr., C.L.4
  • 24
    • 30044436575 scopus 로고    scopus 로고
    • Xenobiotic phenols in early pregnancy amniotic fluid
    • Engel S.M., Levy B., Liu Z., Kaplan D., and Wolff M.S. Xenobiotic phenols in early pregnancy amniotic fluid. Reprod Toxicol 21 1 (2006) 110-112
    • (2006) Reprod Toxicol , vol.21 , Issue.1 , pp. 110-112
    • Engel, S.M.1    Levy, B.2    Liu, Z.3    Kaplan, D.4    Wolff, M.S.5
  • 25
    • 23744472139 scopus 로고    scopus 로고
    • Fetal exposure to phytoestrogens - the difference in phytoestrogen status between mother and fetus
    • Todaka E., Sakurai K., Fukata H., Miyagawa H., Uzuki M., Omori M., et al. Fetal exposure to phytoestrogens - the difference in phytoestrogen status between mother and fetus. Environ Res 99 2 (2005) 195-203
    • (2005) Environ Res , vol.99 , Issue.2 , pp. 195-203
    • Todaka, E.1    Sakurai, K.2    Fukata, H.3    Miyagawa, H.4    Uzuki, M.5    Omori, M.6
  • 26
    • 34250777876 scopus 로고    scopus 로고
    • Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations
    • Mustafa A.M., Malintan N.T., Seelan S., Zhan Z., Mohamed Z., Hassan J., et al. Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations. Toxicol Appl Pharmacol 222 1 (2007) 25-32
    • (2007) Toxicol Appl Pharmacol , vol.222 , Issue.1 , pp. 25-32
    • Mustafa, A.M.1    Malintan, N.T.2    Seelan, S.3    Zhan, Z.4    Mohamed, Z.5    Hassan, J.6
  • 27
    • 0034062036 scopus 로고    scopus 로고
    • Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry
    • Doerge D.R., Chang H.C., Churchwell M.I., and Holder C.L. Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry. Drug Metab Dispos 28 3 (2000) 298-307
    • (2000) Drug Metab Dispos , vol.28 , Issue.3 , pp. 298-307
    • Doerge, D.R.1    Chang, H.C.2    Churchwell, M.I.3    Holder, C.L.4
  • 29
    • 3242697694 scopus 로고    scopus 로고
    • Human placental glucuronidation and transport of 3′azido-3′-deoxythymidine and uridine diphosphate glucuronic acid
    • Collier A.C., Keelan J.A., Van Zijl P.E., Paxton J.W., Mitchell M.D., and Tingle M.D. Human placental glucuronidation and transport of 3′azido-3′-deoxythymidine and uridine diphosphate glucuronic acid. Drug Metab Dispos 32 8 (2004) 813-820
    • (2004) Drug Metab Dispos , vol.32 , Issue.8 , pp. 813-820
    • Collier, A.C.1    Keelan, J.A.2    Van Zijl, P.E.3    Paxton, J.W.4    Mitchell, M.D.5    Tingle, M.D.6
  • 32
    • 0021276426 scopus 로고
    • The effects of the components of the renin-angiotensin system on the isolated perfused human placental cotyledon
    • Glance D.G., Elder M.G., Bloxam D.L., and Myatt L. The effects of the components of the renin-angiotensin system on the isolated perfused human placental cotyledon. Am J Obstet Gynecol 149 4 (1984) 450-454
    • (1984) Am J Obstet Gynecol , vol.149 , Issue.4 , pp. 450-454
    • Glance, D.G.1    Elder, M.G.2    Bloxam, D.L.3    Myatt, L.4
  • 33
    • 0141704078 scopus 로고    scopus 로고
    • Marginal transfer of ReoPro (Abciximab) compared with immunoglobulin G (F105), inulin and water in the perfused human placenta in vitro
    • Miller R.K., Mace K., Polliotti B., DeRita R., Hall W., and Treacy G. Marginal transfer of ReoPro (Abciximab) compared with immunoglobulin G (F105), inulin and water in the perfused human placenta in vitro. Placenta 24 7 (2003) 727-738
    • (2003) Placenta , vol.24 , Issue.7 , pp. 727-738
    • Miller, R.K.1    Mace, K.2    Polliotti, B.3    DeRita, R.4    Hall, W.5    Treacy, G.6
  • 34
    • 33745253793 scopus 로고    scopus 로고
    • Perfusion studies of glyburide transfer across the human placenta: implications for fetal safety
    • Kraemer J., Klein J., Lubetsky A., and Koren G. Perfusion studies of glyburide transfer across the human placenta: implications for fetal safety. Am J Obstet Gynecol 195 1 (2006) 270-274
    • (2006) Am J Obstet Gynecol , vol.195 , Issue.1 , pp. 270-274
    • Kraemer, J.1    Klein, J.2    Lubetsky, A.3    Koren, G.4
  • 35
    • 0023026826 scopus 로고
    • Effect of fetal and maternal intravascular antipyrine infusion on maternal plasma prostaglandin concentrations in the pregnant sheep at 104 to 127 days' gestation
    • Pimentel G., Figueroa J.P., Mitchell M.D., Massmann A., and Nathanielsz P.W. Effect of fetal and maternal intravascular antipyrine infusion on maternal plasma prostaglandin concentrations in the pregnant sheep at 104 to 127 days' gestation. Am J Obstet Gynecol 155 6 (1986) 1181-1185
    • (1986) Am J Obstet Gynecol , vol.155 , Issue.6 , pp. 1181-1185
    • Pimentel, G.1    Figueroa, J.P.2    Mitchell, M.D.3    Massmann, A.4    Nathanielsz, P.W.5
  • 37
    • 1642299877 scopus 로고    scopus 로고
    • An examination of whether human placental perfusion allows accurate prediction of placental drug transport: studies with diazepam
    • Myllynen P., and Vahakangas K. An examination of whether human placental perfusion allows accurate prediction of placental drug transport: studies with diazepam. J Pharmacol Toxicol Methods 48 3 (2002) 131-138
    • (2002) J Pharmacol Toxicol Methods , vol.48 , Issue.3 , pp. 131-138
    • Myllynen, P.1    Vahakangas, K.2
  • 38
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
    • Imai Y., Tsukahara S., Asada S., and Sugimoto Y. Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res 64 12 (2004) 4346-4352
    • (2004) Cancer Res , vol.64 , Issue.12 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 39
    • 34248186154 scopus 로고    scopus 로고
    • Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor
    • Yeboah D., Sun M., Kingdom J., Baczyk D., Lye S.J., Matthews S.G., et al. Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor. Can J Physiol Pharmacol 84 12 (2006) 1251-1258
    • (2006) Can J Physiol Pharmacol , vol.84 , Issue.12 , pp. 1251-1258
    • Yeboah, D.1    Sun, M.2    Kingdom, J.3    Baczyk, D.4    Lye, S.J.5    Matthews, S.G.6
  • 40
    • 33646471830 scopus 로고    scopus 로고
    • ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast
    • Evseenko D.A., Paxton J.W., and Keelan J.A. ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast. Am J Physiol Regul Integr Comp Physiol 290 5 (2006) R1357-R1365
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290 , Issue.5
    • Evseenko, D.A.1    Paxton, J.W.2    Keelan, J.A.3
  • 41
    • 34748926909 scopus 로고    scopus 로고
    • Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens
    • Enokizono J., Kusuhara H., and Sugiyama Y. Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens. Mol Pharmacol 72 4 (2007) 967-975
    • (2007) Mol Pharmacol , vol.72 , Issue.4 , pp. 967-975
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 42
    • 33846207538 scopus 로고    scopus 로고
    • Active transport across the human placenta: impact on drug efficacy and toxicity
    • Evseenko D., Paxton J.W., and Keelan J.A. Active transport across the human placenta: impact on drug efficacy and toxicity. Expert Opin Drug Metab Toxicol 2 1 (2006) 51-69
    • (2006) Expert Opin Drug Metab Toxicol , vol.2 , Issue.1 , pp. 51-69
    • Evseenko, D.1    Paxton, J.W.2    Keelan, J.A.3
  • 43
    • 25844485913 scopus 로고    scopus 로고
    • P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages
    • Mathias A.A., Hitti J., and Unadkat J.D. P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages. Am J Physiol Regul Integr Comp Physiol 289 4 (2005) R963-R969
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289 , Issue.4
    • Mathias, A.A.1    Hitti, J.2    Unadkat, J.D.3
  • 44
    • 70350049066 scopus 로고    scopus 로고
    • Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones
    • Tang L., Singh R., Liu Z., and Hu M. Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones. Mol Pharm 6 5 (2009) 1466-1482
    • (2009) Mol Pharm , vol.6 , Issue.5 , pp. 1466-1482
    • Tang, L.1    Singh, R.2    Liu, Z.3    Hu, M.4
  • 45
    • 3042725709 scopus 로고    scopus 로고
    • Drug transfer and metabolism by the human placenta
    • Syme M.R., Paxton J.W., and Keelan J.A. Drug transfer and metabolism by the human placenta. Clin Pharmacokinet 43 8 (2004) 487-514
    • (2004) Clin Pharmacokinet , vol.43 , Issue.8 , pp. 487-514
    • Syme, M.R.1    Paxton, J.W.2    Keelan, J.A.3
  • 46
    • 0036471022 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term
    • Collier A.C., Ganley N.A., Tingle M.D., Blumenstein M., Marvin K.W., Paxton J.W., et al. UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term. Biochem Pharmacol 63 3 (2002) 409-419
    • (2002) Biochem Pharmacol , vol.63 , Issue.3 , pp. 409-419
    • Collier, A.C.1    Ganley, N.A.2    Tingle, M.D.3    Blumenstein, M.4    Marvin, K.W.5    Paxton, J.W.6
  • 47
    • 0036799064 scopus 로고    scopus 로고
    • Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption
    • Collier A.C., Tingle M.D., Paxton J.W., Mitchell M.D., and Keelan J.A. Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption. Hum Reprod 17 10 (2002) 2564-2572
    • (2002) Hum Reprod , vol.17 , Issue.10 , pp. 2564-2572
    • Collier, A.C.1    Tingle, M.D.2    Paxton, J.W.3    Mitchell, M.D.4    Keelan, J.A.5
  • 48
    • 0024340713 scopus 로고
    • Immunological characterization of human phenol sulfotransferase
    • Heroux J.A., Falany C.N., and Roth J.A. Immunological characterization of human phenol sulfotransferase. Mol Pharmacol 36 1 (1989) 29-33
    • (1989) Mol Pharmacol , vol.36 , Issue.1 , pp. 29-33
    • Heroux, J.A.1    Falany, C.N.2    Roth, J.A.3
  • 49
    • 0036174950 scopus 로고    scopus 로고
    • Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy
    • Matsumoto J., Yokota H., and Yuasa A. Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy. Environ Health Perspect 110 2 (2002) 193-196
    • (2002) Environ Health Perspect , vol.110 , Issue.2 , pp. 193-196
    • Matsumoto, J.1    Yokota, H.2    Yuasa, A.3
  • 50
    • 0024272881 scopus 로고
    • The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes
    • Coughtrie M.W., Burchell B., Leakey J.E., and Hume R. The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes. Mol Pharmacol 34 6 (1988) 729-735
    • (1988) Mol Pharmacol , vol.34 , Issue.6 , pp. 729-735
    • Coughtrie, M.W.1    Burchell, B.2    Leakey, J.E.3    Hume, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.