Artificial microRNA-based neurokinin-1 receptor gene silencing reduces alcohol consumption in mice

Neuroscience Letters

Volumn 475, Issue 3, 2010, Pages 124-128

  Baek, Mi Na ^a   Jung, Kyoung Hwa ^a   Halder, Debasish ^a   Choi, Mi Ran ^a   Lee, Byung Hwa ^a   Lee, Boung Chul ^b   Jung, Myung Hun ^b   Choi, Ihn Geun ^b   Chung, Mi Kyung ^c   Oh, Dong Yul ^d   Chai, Young Gyu ^a  

^a Hanyang University   (South Korea)

^b Hallym University   (South Korea)

^c CHA University   (South Korea)

^d Kwandong University College of Medicine   (South Korea)

Author keywords

Alcohol consumption; Alcohol dependence; Artificial microRNA; Lentivirus; Neurokinin 1 receptor (NK1R)

Indexed keywords

ARTIFICIAL MICRORNA; MICRORNA; NALTREXONE; NEUROKININ 1 RECEPTOR; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG TARGETING; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE SILENCING; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RNA INTERFERENCE; VIRAL GENE DELIVERY SYSTEM;

ALCOHOL DRINKING; ANIMALS; BRAIN; GENE KNOCKDOWN TECHNIQUES; LENTIVIRUS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; NALTREXONE; NARCOTIC ANTAGONISTS; RECEPTORS, NEUROKININ-1; RNA INTERFERENCE;

EID: 77952545540     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.03.051     Document Type: Article

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