Synthesis and structure-activity relationships of mono- and dialkyl-substituted oxaliplatin derivatives

European Journal of Medicinal Chemistry

Volumn 40, Issue 11, 2005, Pages 1149-1155

  Habala, Ladislav ^a   Galanski, Mathea S ^a   Yasemi, Afshin ^a   Nazarov, Alexey A ^a   Von Keyserlingk, Nikolai Graf ^b   Keppler, Bernhard K ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Faustus Forschungs Compagnie Translational Cancer Research GmbH   (Germany)

Author keywords

Anticancer complexes; Cytotoxic activity; Oxaliplatin; Platinum; Structure activity relationships (SAR)

Indexed keywords

(4 ETHYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (4 METHYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (4 TERT BUTYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (4,4 DIMETHYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (4,5 DIMETHYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (CYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; ANTINEOPLASTIC AGENT; CARBON; OXALIPLATIN; PLATINUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; RACEMIC MIXTURE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 26844514573     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.06.003     Document Type: Article

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