Characterisation of the hepatic progenitor cell compartment in normal liver and in hepatitis: An immunohistochemical comparison between dog and man

Veterinary Journal

Volumn 184, Issue 3, 2010, Pages 308-314

  IJzer, J ^a   Schotanus, B A ^b   Vander Borght, S ^c   Roskams, T A D ^c   Kisjes, R ^a   Penning, L C ^b   Rothuizen, J ^b   van den Ingh, T S G A M ^d  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d TCCI Consultancy BV   (Netherlands)

Author keywords

Dog; Hepatitis; Immunohistochemistry; Liver; Progenitor cells

Indexed keywords

BIOLOGICAL MARKER; BREAST CANCER RESISTANCE PROTEIN; CYTOKERATIN 7; LIVER PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; PARAFFIN; PROTEIN HEP PAR 1; UNCLASSIFIED DRUG;

ACUTE HEPATITIS; ANIMAL CELL; ARTICLE; BILE DUCT; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOG DISEASE; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER DISEASE; NONHUMAN; PROTEIN EXPRESSION; SPECIES COMPARISON; STEM CELL;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DOGS; HEPATITIS; HEPATITIS, ANIMAL; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-7; LIVER; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; SPECIES SPECIFICITY; STEM CELLS;

CANIS FAMILIARIS;

EID: 77952543808     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2009.02.016     Document Type: Article

References (27)

1. Alison M.R. Characterization of the differentiation capacity of rat-derived hepatic stem cells. Seminars in Liver Disease 2003, 23:325-336.
2. Arends B., Spee B., Hoffmann G., Jansen G.E., Slump E., Auriemma E., IJzer J., Hemrika W., Romijn R.A., van der Heijden-Liefkens K.H., Sondermeijer P.J., van den Ingh T.S., Penning L.C., Rothuizen J. In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor. The Veterinary Journal 2008, 178:70-77.
3. Borst P., Elferink R.O. Mammalian ABC transporters in health and disease. Annual Reviews in Biochemistry 2002, 71:537-592.
4. Hixson D.C., Chapman L., McBride A., Faris R., Yang L. Antigenic phenotypes common to rat oval cells, primary hepatocellular carcinomas and developing bile ducts. Carcinogenesis 1997, 18:1169-1175.
5. IJzer, J., Kisjes, J.R., Penning, L.C., Rothuizen, J., van den Ingh, T.S.G.A.M., 2009. The progenitor cell compartment in the feline liver: An (immuno)histochemical investigation. Veterinary Pathology, 46(4).
6. Iredale J.P. Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ. Journal of Clinical Investigation 2007, 117:539-548.
7. Katoonizadeh A., Nevens F., Verslype C., Pirenne J., Roskams T. Liver regeneration in acute severe liver impairment: A clinicopathological correlation study. Liver International 2006, 26:1225-1233.
8. Libbrecht L., Desmet V., Van Damme B., Roskams T. Deep intralobular extension of human hepatic 'progenitor cells' correlates with parenchymal inflammation in chronic viral hepatitis: Can 'progenitor cells' migrate?. Journal of Pathology 2000, 192:373-378.
9. Lowes K.N., Brennan B.A., Yeoh G.C., Olynyk J.K. Oval cell numbers in human chronic liver diseases are directly related to disease severity. American Journal of Pathology 1999, 154:537-541.
10. Michalopoulos G.K. Hepatocyte growth factor in liver growth and differentiation. Liver Growth and Repair 1998, 219-231. Chapman & Hall Ltd., London, Great Britain. A.J. Strain, A.M. Diehl (Eds.).
11. Michalopoulos G.K., DeFrances M.C. Liver regeneration. Science 1997, 276:60-66.
12. Ramos-Vara J.A., Miller M.A., Johnson G.C. Immunohistochemical characterization of canine hyperplastic hepatic lesions and hepatocellular and biliary neoplasms with monoclonal antibody hepatocyte paraffin 1 and a monoclonal antibody to cytokeratin 7. Veterinary Pathology 2001, 38:636-643.
13. Rao M.S., Khan A.A., Parveen N., Habeeb M.A., Habibullah C.M., Pande G. Characterization of hepatic progenitors from human fetal liver during second trimester. World Journal of Gastroenterology 2008, 14:5730-5737.
14. Ros J.E., Libbrecht L., Geuken M., Jansen P.L., Roskams T.A. High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease. Journal of Pathology 2003, 200:553-560.
15. Ros J.E., Roskams T.A., Geuken M., Havinga R., Splinter P.L., Petersen B.E., LaRusso N.F., van der Kolk D.M., Kuipers F., Faber K.N., Muller M., Jansen P.L. ATP binding cassette transporter gene expression in rat liver progenitor cells. Gut 2003, 52:1060-1067.
16. Roskams T., De Vos R., Van Eyken P., Myazaki H., Van Damme B., Desmet V. Hepatic OV-6 expression in human liver disease and rat experiments: Evidence for hepatic progenitor cells in man. Journal of Hepatology 1998, 29:455-463.
17. Roskams T.A., Libbrecht L., Desmet V.J. Progenitor cells in diseased human liver. Seminars in Liver Disease 2003, 23:385-396.
18. Roskams T., Cassiman D., De Vos R., Libbrecht L. Neuroregulation of the neuroendocrine compartment of the liver. The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology 2004, 280:910-923. 2004.
19. Roskams T.A., Theise N.D., Balabaud C., Bhagat G., Bhathal P.S., Bioulac-Sage P., Brunt E.M., Crawford J.M., Crosby H.A., Desmet V., Finegold M.J., Geller S.A., Gouw A.S.H., Hytiroglou P., Knisely A.S., Kojiro M., Lefkowitch J.H., Nakanuma Y., Olynyk J.K., Park Y.N., Portmann B., Saxena R., Scheuer P.J., Strain A.J., Thung S.N., Wanless I.R., West A.B. Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers. Hepatology 2004, 39:1739-1745.
20. Santoni-Rugiu E., Jelnes P., Thorgeirsson S.S., Bisgaard H.C. Progenitor cells in liver regeneration: Molecular responses controlling their activation and expansion. Acta pathologic, Microbiologica et Immunologica Scandinavica 2005, 113:876-902.
21. Spee B., Arends B., van den Ingh T.S., Brinkhof B., Nederbragt H., IJzer J., Roskams T.A.D., Penning L.C., Rothuisen J. Transforming growth factor beta-1 signalling in canine hepatic diseases: New models for human fibrotic liver pathologies. Liver International 2006, 26:716-725.
22. Tan J., Hytiroglou P., Wieczorek R., Park Y.N., Thung S.N., Arias B., Theise N.D. Immunohistochemical evidence for hepatic progenitor cells in liver diseases. Liver 2002, 22:365-373.
23. van den Ingh T.S.G.A.M., Van Winkle T., Cullen J.M., Charles J.A., Desmet V.J. Morphological classification of parenchymal disorders of the canine and feline liver: 2 hepatocellular death, hepatitis and cirrhosis. WSAVA Liver Standardization Group: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases 2006, 85-102. Saunders-Elsevier, Edinburgh, Great Britain. J. Rothuizen, S.E. Bunch, J.A. Charles, J.M. Cullen, V.J. Desmet, V. Szatmari, D.C. Twedt, T.S.G.A.M. van den Ingh, T. Van Winkle, R.J. Washabau (Eds.).
24. Vander Borght S., Libbrecht L., Katoonizadeh A., van Pelt J., Cassiman D., Nevens F., Van Lommel A., Petersen B.E., Fevery J., Jansen P.L., Roskams T.A. Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: Possible functional consequences. Journal of Histochemistry and Cytochemistry 2006, 54:1051-1059.
25. Yoshioka K., Enaga S., Taniguchi K., Fukushima U., Uechi M., Mutoh K. Morphological characterization of ductular reactions in canine liver disease. Journal of Comparative Pathology 2004, 130:92-98.
26. Yovchev M.I., Grozdanov P.N., Joseph B., Gupta S., Dabeva M.D. Novel hepatic progenitor surface cell markers in the adult rat liver. Hepatology 2007, 45:139-149.
27. Zhou H., Rogler L.E., Teperman L., Morgan G., Rogler C.E. Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver. Hepatology 2007, 45:716-724.