The progenitor cell compartment in the feline liver: An (immuno)histochemical investigation

Veterinary Pathology

Volumn 46, Issue 4, 2009, Pages 614-621

  IJzer, J ^a   Kisjes, J R ^a   Penning, L C ^b   Rothuizen, J ^b   Van Den Ingh, T S G A M ^c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c TCCI Consultancy BV   (Netherlands)

Author keywords

Cats; Ductular reaction; Immunohistochemistry; Liver; Progenitor cells

Indexed keywords

CYTOKERATIN 7; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2;

ANIMAL; ANIMAL DISEASE; ARTICLE; CAT; CYTOLOGY; IMMUNOHISTOCHEMISTRY; LIVER; STEM CELL;

ANIMALS; CATS; IMMUNOHISTOCHEMISTRY; KERATIN-7; LIVER; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; STEM CELLS;

CANIS FAMILIARIS; FELIDAE;

EID: 67650879495     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1354/vp.07-VP-0097-I-FL     Document Type: Article

References (25)

1. Borst P, Elferink RO: Mammalian ABC transporters in health and disease. Annu Rev Biochem 71: 537-592, 2002
2. Cullen JM, van den Ingh TSGAM, Van Winkle T, Charles JA, Desmet VJ: Morphological classification of parenchymal disorders in the canine and feline liver: 1 Normal histology, reversible hepatocytic injury and hepatic amyloidosis. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Disease, ed. Rothuizen J, Bunch SE, Charles JA, Cullen JM, Desmet VJ, and Szatmari V, et al. 2006
3. Fausto N: Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 39:1477-1487, 2004
4. Hatch HM, Zheng D, Jorgensen ML, Petersen BE: SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells 4:339-351, 2002
5. Hixson DC, Chapman L, McBride A, Faris R, Yang L: Antigenic phenotypes common to rat oval cells, primary hepatocellular carcinomas and developing bile ducts. Carcinogenesis 18:1169-1175, 1997
6. IJzer J, Schotanus BA, Vander Borght S, Roskams TAD, Kisjes JR, Penning LC, et al.: Characterization of the hepatic progenitor cell compartment in acute and chronic hepatitis and in the normal liver: a comparative immunohistochemical study in dog and man. (in press) 2007
7. Kallis YN, Alison MR, Forbes SJ: Bone marrow stem cells and liver disease. Gut 56:716-724, 2007
8. Katoonizadeh A, Nevens F, Verslype C, Pirenne J, Roskams T: Liver regeneration in acute severe liver impairment: a clinicopathological correlation study. Liver Int 26:1225-1233, 2006
9. Michalopoulos GK: Liver regeneration. J Cell Physiol 2007
10. Michalopoulos GK, Barua L, Bowen WC: Trans-differentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury. Hepatology 41:535-544, 2005
11. Oh SH, Witek RP, Bae SH, Zheng D, Jung Y, Piscaglia AC, et al.: Bone marrow-derived hepatic oval cells differentiate into hepatocytes in 2-acetyl-aminofluorene/partial hepatectomy-induced liver regeneration. Gastroenterology 132:1077-1087, 2007
12. Preisegger KH, Factor VM, Fuchsbichler A, Stumptner C, Denk H, Thorgeirsson SS: Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4- dihydrocollidine mouse model for chronic alcoholic liver disease. Lab Invest 79:103-109, 1999
13. Roskams T, Cassiman D, De Vos R, Libbrecht L: Neuroregulation of the neuroendocrine compartment of the liver. Anat Rec A Discov Mol Cell Evol Biol 280:910-923, 2004
14. Roskams T, De Vos R, Van Eyken P, Myazaki H, Van Damme B, Desmet V: Hepatic OV-6 expression in human liver disease and rat experiments: evidence for hepatic progenitor cells in man. J Hepatol 29:455-463, 1998
15. Roskams T, Yang SQ, Koteish A, Durnez A, DeVos R, Huang X, et al.: Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. Am J Pathol 163:1301-1311, 2003
16. Roskams TA, Libbrecht L, Desmet VJ: Progenitor cells in diseased human liver. Semin Liver Dis 23:385-396, 2003
17. Roskams TA, Theise ND, Balabaud C, Bhagat G, Bhathal PS, Bioulac-Sage P, et al.: Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers. Hepatology 39:1739-1745, 2004
18. Santoni-Rugiu E, Jelnes P, Thorgeirsson SS, Bisgaard HC: Progenitor cells in liver regeneration: molecular responses controlling their activation and expansion. APMIS 113:876-902, 2005
19. Tan J, Hytiroglou P, Wieczorek R, Park YN, Thung SN, Arias B, et al.: Immunohistochemical evidence for hepatic progenitor cells in liver diseases. Liver 22:365-373, 2002
20. van den Ingh TS, Rothuizen J, Cupery R: Chronic active hepatitis with cirrhosis in the Doberman pinscher. Vet Q 10:84-89, 1988
21. van den Ingh TSGAM, Cullen JM, Twedt DC, Van Winkle T, Desmet VJ, Rothuizen J: Morphological classification of biliary disorders of the canine and feline liver. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases, ed. Rothuizen J, Bunch SE, Charles JA, Cullen JM, Desmet VJ, and Szatmari V, et al. 2006
22. van den Ingh TSGAM, Van Winkle T, Cullen JM, Charles JA, Desmet VJ: Morphological classification of parenchymal disorders of the canine and feline liver: 2. Hepatocellular death, hepatitis and cirrhosis. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases, ed. WSAVA liver standardization group: Rothuizen J, Bunch SE, Charles JA, Cullen JM, Desmet VJ, and Szatmari V, et al. 2006
23. Van Winkle T, Cullen JM, van den Ingh TSGAM, Charles JA, Desmet VJ: Morphological classification of parenchymal disorders of the canine and feline liver: 3. Hepatic abcesses and granulomas, hepatic metabolic storage disorders and miscellaneous conditions. In: WSAVA Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases, ed. Rothuizen J, Bunch SE, Charles JA, Cullen JM, Desmet VJ, and Szatmari V, et al. 2006
24. Yang S, Koteish A, Lin H, Huang J, Roskams T, Dawson V, et al.: Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. Hepatology 39:403-411, 2004
25. Zhou H, Rogler LE, Teperman L, Morgan G, Rogler CE: Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver. Hepatology 45:716-724, 2007