Management of hyperglycaemia in acute coronary syndrome

British Journal of Diabetes and Vascular Disease

Volumn 10, Issue 2, 2010, Pages 59-65

  Devine, Matthew J ^a   Chandrasekara, Wasala M H S ^b   Hardy, Kevin J ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ST HELENS AND KNOWSLEY TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Acute coronary syndrome; Diabetes; Hyperglycaemia

Indexed keywords

GLUCOSE; INSULIN; POTASSIUM;

ACUTE CORONARY SYNDROME; CLINICAL TRIAL; DRUG INFUSION; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; HEART MUSCLE ISCHEMIA; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN TREATMENT; LOW DRUG DOSE; MORTALITY; REVIEW; VASOCONSTRICTION;

EID: 77952498343     PISSN: 14746514     EISSN: None     Source Type: Journal    
DOI: 10.1177/1474651409357480     Document Type: Review

References (29)

1. Allender S, Peto V, Scarborough P et al. Coronary Heart Disease Statistics. London: BHF, 2007.
2. National Diabetes Support Team. Improving Emergency and Inpatient Care for People with Diabetes. March 2008. Leicester: NDST, 2008.
3. Norhammar A, Tenerz A, Nilsson G et al. Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study. Lancet 2002;359:2140-2144
4. Stranders I, Diamant M, Van Gelder RE et al. Admission blood glucose level as risk indicator of death after myocardial infarction in patients with and without diabetes mellitus. Arch Intern Med 2004;164: 982-988
5. Marfella R, Verrazzo G, Acampora R et al. Glutathione reverses systemic hemodynamic changes by acute hyperglycemia in healthy subjects. Am J Physiol 1995;268:E1 167-173
6. Kawano H, Motoyama T, Hirashima O et al. Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. J Am Coll Cardiol 1999;34:146-154
7. Ishihara M, Inoue I, Kawagoe T et al. Impact of acute hyperglycemia on left ventricular function after reperfusion therapy in patients with a first anterior wall acute myocardial infarction. Am Heart J 2003;146:674-678 (Pubitemid 37281713)
8. Marfella R, Nappo F, De Angelis L et al. The effect of acute hyperglycemia on QTc duration in healthy man. Diabetologia 2000;43:571-575
9. Libby P, Marroko PR, Braunwald E. The effects of hypoglycaemia on myocardial ischaemic injury during acute experimental coronary artery occlusion. Circulation 1975;51:621-626
10. Kosiborod M, Inzucchi SE, Goyal A et al. Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction. JAMA 2009;301:1556-1564
11. Weston C, Walker L, Birkhead J. Early impact of insulin treatment on mortality for hyperglycaemic patients without known diabetes who present with an acute coronary syndrome. Heart 2007;93:1542-1546
12. Kosiborod M, Rathore SS, Inzucchi SE et al. Admission glucose and mortality in elderly patients hospitalised with acute myocardial infarction: implications for patients with and without recognised diabetes. Circulation 2005;111:3078-3086
13. Malmberg K, Ryden L, Efendic S et al. Randomised trial of Insulin glucose Infusion followed by subcutaneous Insulin treatment In diabetic patients with acute myocardial infarction (DIGAMI Study): effects on mortality at 1 year. J Am Coll Cardiol 1995;26:57-65.
14. Van Den Berghe G, Wouters P, Weekers F et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001;345:1359-1367
15. Van den Berghe G, Wilmer A, Hermans G et al. Intensive insulin therapy in the medical ICU. N Engl J Med 2006;354:449-461
16. Furnary AP, Gao G, Grunkemeier GL et al. Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 2003;125:1007-1021
17. Gandhi GY, Nuttall GA, Abel MD et al. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery. Ann Intern Med 2007;146:233-243
18. Golden SH, Camille PV, Kao WHL, Brancat F. Perioperative glycaemic control and the risk of infectious complications in a cohort of adults with diabetes. Diabetes Care 1999;22:1408-1414
19. Furnary AP, Zerr KJ, Grunkemeier GL, Starr A. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg 1999;67:352-362
20. Malmberg K, Ryden L, Wedel H et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2); effects on mortality and morbidity. Eur Heart J 2005;26:650-661
21. Diaz R, Paolasso EC, Piegas LS et al. Metabolic modulation of acute myocardial infarction: the ECLA glucose-insulin-potassium pilot trial. Circulation 1998;98:2227-2234
22. The CREATE-ECLA Trial Group Investigators: Effect of glucose-insulin- potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction. JAMA 2005;293:437-446
23. Ceremuzytński L, Budaj A, Czepiel A et al. Low-dose glucose-insulin-potassium is ineffective in acute myocardial infarction: results of a randomized multicenter Pol-GIK trial. Cardiovasc Drugs Ther 1999; 13:185-189
24. Cheung NW, Wong VW, McLean M. The Hyperglycaemia: Intensive Insulin infusion In Infarction (HI-5) Study: A randomised controlled trial of insulin infusion therapy for myocardial infarction. Diabetes Care 2006;29:765-770
25. The Immediate Metabolic Myocardial Enhancement During Initial Assessment and Treatment in Emergency (IMMEDIATE) care study. www.clinicaltrials.gov/show/ NCT00091507 (Accessed 14 July 2008).
26. INTENSIVE Trial. www.sanofi-aventis.ca/live/ca/medias/CC1E2A67-6117-4B3E- 8077-7CD98621BD50.pdf (Accessed 14 July 2008).
27. Opie LH. Metabolic management of acute myocardial infarction comes to the fore and extends beyond control of hyperglycemia. Circulation 2008;117:2172-2177
28. Diaz R, Goyal A, Mehta SR et al. Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. JAMA 2007;298:2399-2405
29. Chaudhuri A, Miller M, Nesto R et al. Targeting glucose in acute myocardial infarction: has glucose, insulin, and potassium infusion missed the target? Diabetes Care 2007;30:3026-3028