Antioxidant and antihyperlipidaemic activity of protocatechuic acid on streptozotocindiabetic rats

Redox Report

Volumn 15, Issue 2, 2010, Pages 71-80

  Harini, Ranganathan ^a   Pugalendi, Kodukkur Viswanathan ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidant; Diabetes; Hyperlipidaemia; Oxidative stress; Protocatechuic acid

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; GLIBENCLAMIDE; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID HYDROPEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTOCATECHUIC ACID; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG ANALYSIS; DRUG DOSE COMPARISON; DRUG MECHANISM; HISTOPATHOLOGY; HYPERLIPIDEMIA; LIPID COMPOSITION; LIPOPROTEIN BLOOD LEVEL; LIVER PROTECTION; MALE; MORNING DOSAGE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RENAL PROTECTION; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTILIPEMIC AGENTS; ANTIOXIDANTS; ASCORBIC ACID; DIABETES MELLITUS, EXPERIMENTAL; GLUTATHIONE; HYDROXYBENZOIC ACIDS; KIDNEY; LIPID PEROXIDES; LIVER; MALE; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VITAMIN E;

RATTUS;

EID: 77952496651     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/174329210X12650506623285     Document Type: Article

References (46)

1. Halliwell B, Gutteridge J M C. Role of free radicals and catalytic metal ions in human disease. Methods Enzymol 1990;186:1-88.
2. King GL, Loken MR. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004;122:333-338.
3. Abu-seif MA, Youseef AA. Evaluation of some biochemical changes in diabetic patients. Clin Chim Acta 2004;346:161-170.
4. Deedwania PC, Hunninghake DB, Bays H. Effects of lipid-altering treatment in diabetes mellitus and metabolic syndrome. Am J Cardiol 2004;93:18c-20c.
5. Huang MT, Ferrano T. Phenolic compounds in food and cancer prevention. In: Huang MD, Ho CT, Lee CY. (eds). Phenolic Compounds in Food and Their Effects on Health: Antioxidants and Cancer Prevention. Washington, DC: American Chemical Society, 1992.
6. Chan K, Chui SH, Wong DY et al. Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction-. Life Sci 2004;75:3157-3171.
7. Chuen-Lan L, Jin-Ming W, Chia-Yih C et al. In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity. Food Chem Toxicol 2002;40:635-641.
8. Tanaka T, Kojima T, Kawamori T et al. Chemoprevention diethylnitrosamine-induced hepatocarcinogenesis by a simple phenolic acid protocatechuic acid in rats. Can Res 1993;53:2775-2779.
9. Niehaus WG, Samuelson B. Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem 1968;6:126-130.
10. Jiang ZY, Hunt JV, Wolff SP. Detection of lipid hydroperoxides using the -fox method-. Anal Biochem 1992;202:384-389.
11. Kakkar P, Das B, Viswanathan PN. A modified spectrophotometric assay of superoxide dismutase. Ind J Biochem Biophys 1984;21:130-132.
12. Sinha KA, Colorimetric assay of catalase. Anal Biochem 1972;47:389-394.
13. Rotruck JJ, Pope AL, Ganther HE et al. Selenium: biochemical rates as a component of glutathione peroxidase. Science 1973;179:588-590.
14. Ellman GL. Tissue sulphydryl groups. Arch Biochem Biophys 1959;82:70-77.
15. Roe JH, Kuether CA. Detection of ascorbic acid in whole blood and urine through 2, 4-DNPH derivative of dehydroascorbic acid. J Biol Chem 1943;47:399-407.
16. Baker H. Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol. Nutr Rep Int 1980;21:531-536.
17. Folch J, Lees M, Sloane Stanly GH. A simple method for isolation and purification of total lipids from animal tissues. J Biol Chem 1957;26:497-509.
18. Allain, CC, Poon LS, Chan CS et al. Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-475.
19. Izzo C, Grillo F, Murador E. Improved method for the determination of high density lipoprotein cholesterol. Isolation of high-density lipoproteins by the use of polyethylene glycol 6000. Clin Chem 1981;27:371-374.
20. Friedewald WT, Levy RI, Fredrickson DS. Estimation of LDL- cholesterol in the plasma, without the use of preparative ultracentrifuge. Clin Chem 1972;18:449.
21. McGowan MW, Artiss JD, Strandbergh DR et al. A peroxidasecoupled method for the colorimetric determination of serum triglycerides. Clin Chem 1983;29:538-542.
22. Falholt K, Lund B, Falholt W. An easy colorimetric method for routine determination of free fatty acids in the plasma. Clin Chim Acta 1973;46:105-111.
23. Zilversmit DB, Davis AK. Micro-determination of plasma phospholipids by trichloroacetic acid precipitation. J Lab Clin Med 1950;35:155-159.
24. Papaccio G, Pisanti FA, Latronico MV, Ammendola E, Galdieri M. Multiple low-dose and single high-dose treatments with streptozotocin do not generate nitric oxide. J Cell Biochem 2000;77:82-91.
25. Mohamed AK, Bierhaus A, Schiekofer S. The role of oxidative stress and NF-kappaB activation in late diabetic complications. Biofactors 1999;10:157-167.
26. Girotti MW. Mechanisms of lipid peroxidation. Free Radic Biol Med 1985;1:87-95.
27. Zhang XF, Tan BK. Antihyperglycaemic and antioxidant properties of andrographis particulate in normal and diabetic rats. Clin Exp Pharmacol Physiol 2000;27:5-6.
28. Yu BP. Cellular defenses against damage from reactive oxygen species. Physiol Rev 1994;74:136-162.
29. Del Maestro RF. An approach to free radicals in medicine and biology. Acta Physiol Scand Suppl 1980;492:153-168.
30. Andallu B, Varadacharyulu N Ch. Antioxidant role of mulberry (Morus indica L.) leaves in streptozotocin diabetic rats. Clin Chim Acta 2003;338:3-10.
31. Yen GC, Hsieh CL. Inhibitory effects of Du-zhong (Eucommia olmoides oliv.) against low-density lipoprotein oxidative modification. Food Chem 2002;77:449-456.
32. Wefers H, Sies H. The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. Eur J Biochem 1998;174:353-357.
33. Gary M, Bansal DD. Protective antioxidant effect of vitamin C and vitamin E in STZ-induced diabetic rats. Ind J Exp Biol 2000;28:101-104.
34. Jain SK, Levine SN. Elevated lipid peroxidation and vitamin E quinine levels in heart ventricles of streptozotocin treated diabetic rats. Free Radic Biol Med 1995;18:337-341.
35. Asayama K, Nakane T, Uchida N, Hayashibe H, Dobashi K, Nakazawa S. Serum antioxidant status in streptozotocin induced diabetic rats. Horm Metab Res 1994;26:313-315.
36. Yoshida K, Hirokawa J, Tagami S. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia 1995;38:201-210.
37. Halliwell B, Gutteridge J M C. Lipid peroxidation, oxygen radicals, cell damage and antioxidant therapy. Lancet 1994;1:1396-1397.
38. Levine WG. Interaction of ascorbic acid and α-tocopherol. Ann Nutr Acad Sci 1990;498:186-199.
39. Darlin Quine S, Pamakanthan S. Effects of (-) -epicatechin, a flavonoid on lipid peroxidation and antioxidants in streptozotocininduced diabetic liver, kidney and heart. Pharmacol Rep 2005;57:610-615.
40. Fontbonne A, Eschwege E, Cambien F et al. Hypertriglyceridaemia as a risk factor of coronary heart disease mortality in subjects with impaired glucose tolerance or diabetes. Diabetologia 1989;32:300-304.
41. Grudy MS, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV. Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 1999;100:1134-1146.
42. Lusis JA. Atheroscelerosis. Nature 2000;407, 233-241.
43. Kudchodkar BJ, Lee MJ, Lee SM, DiMarco NM, Lacko AG. Effect of dietary protein on cholesterol homeostasis in diabetic rats. J Lipid Res 1988;10:1272-1287.
44. Braun JE, Severson DL. Regulation of the synthesis, processing and translocation of lipoprotein lipase. Biochem J 1992;287:337-347.
45. Lopez-Virella MF, Wholtmann HJ, Mayfield RK, Loadholt CB, Colwell JA. Effect of metabolic control on lipid, lipoprotein, and apolipoprotein levels in 55 insulin-dependent diabetic patients: a longitudinal study. Diabetes 1983;32:20-25.
46. Rhoads GG, Gulbrandse CL, Kagan A. Serum lipoproteins and coronary artery diseases in a population study of Hawaii, a Japanese man-. N Engl J Med 1976;294:293-298.