Impact of lipid raft integrity on 5-HT 3 receptor function and its modulation by antidepressants

Neuropsychopharmacology

Volumn 35, Issue 7, 2010, Pages 1510-1519

  Nothdurfter, Caroline ^a,b   Tanasic, Sascha ^b   Di Benedetto, Barbara ^a,b   Rammes, Gerhard ^b,c   Wagner, Eva Maria ^b   Kirmeier, Thomas ^b   Ganal, Vanessa ^b   Kessler, Julia S ^a,b   Rein, Theo ^b   Holsboer, Florian ^b   Rupprecht, Rainer ^a,b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

5 HT3 receptor; Antidepressants; Cholesterol; Immunocytochemistry; Ligand gated ion channel; Lipid rafts

Indexed keywords

ANTIDEPRESSANT AGENT; BIOLOGICAL MARKER; CHOLESTEROL; DESIPRAMINE; FLOTILIN 1; FLUOXETINE; ION CHANNEL; METHYL BETA CYCLODEXTRIN; SEROTONIN RECEPTOR; SIMVASTATIN; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CENTRIFUGATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LIPID RAFT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WESTERN BLOTTING;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTIDEPRESSIVE AGENTS; BETA-CYCLODEXTRINS; BIOPHYSICS; CHOLESTEROL; DESIPRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC STIMULATION; FLUOXETINE; HUMANS; IMIDAZOLES; MEMBRANE MICRODOMAINS; MEMBRANE POTENTIALS; MICE; NEUROBLASTOMA; PATCH-CLAMP TECHNIQUES; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; SIMVASTATIN; SULFHYDRYL COMPOUNDS; TIME FACTORS; TRANSFECTION;

EID: 77952431020     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.20     Document Type: Article

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