Effects of the isoflavone puerarin and its glycosides on melanogenesis in B16 melanocytes

European Food Research and Technology

Volumn 231, Issue 1, 2010, Pages 75-83

  Choi, Young Mi ^a   Jun, Hee jin ^a   Dawson, Kevin ^b   Rodriguez, Raymond L ^b   Roh, Mi Ran ^a   Jun, Jungae ^a   Choi, Chung Hyo ^c   Shim, Jae Hoon ^c   Lee, ChoongHwan ^d   Lee, Sang Jun ^e   Park, Kwan Hwa ^c   Lee, Sung Joon ^a  

^a Korea University   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Seoul National University   (South Korea)

^d Konkuk University   (South Korea)

^e AmorePacific Corporation   (South Korea)

Author keywords

B16 murine melanocytes; Hypopigmentation; Melanin; Melanogenesis; Microarray analysis; Puerarin; Tyrosinase

Indexed keywords

CONCENTRATION OF; CONCENTRATION-DEPENDENT; DNA MICRO-ARRAY; DOWN-REGULATION; DUAL MECHANISMS; HYPOPIGMENTATION; IN-VITRO; INHIBITORY EFFECT; ISOFLAVONES; KUDZU ROOT; MELANIN CONTENT; MELANOGENESIS; MICROARRAY ANALYSIS; MUSHROOM TYROSINASE; PROTEIN EXPRESSIONS; PUERARIA LOBATA; PUERARIN; RT-PCR ANALYSIS; SOLUBLE DERIVATIVES; TARGET GENES;

CONCENTRATION (PROCESS); GENES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

SUGARS;

BASIDIOMYCOTA; MURINAE; PUERARIA; PUERARIA MONTANA VAR. LOBATA;

EID: 77952425134     PISSN: 14382377     EISSN: 14382385     Source Type: Journal    
DOI: 10.1007/s00217-010-1251-5     Document Type: Article

References (31)

1. Costin GE, Hearing VJ (2007) Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J 21: 976-994.
2. Iwata M, Corn T, Iwata S, Everett MA, Fuller BB (1990) The relationship between tyrosinase activity and skin color in human foreskins. J Invest Dermatol 95: 9-15.
3. del Marmol V, Beermann F (1996) Tyrosinase and related proteins in mammalian pigmentation. FEBS Lett 381: 165-168.
4. Hearing VJ, Jimenez M (1987) Mammalian tyrosinase-the critical regulatory control point in melanocyte pigmentation. Int J Biochem 19: 1141-1147.
5. Yokoyama K, Yasumoto K, Suzuki H, Shibahara S (1994) Cloning of the human dopachrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression. J Biol Chem 269: 27080-27087.
6. Kobayashi T, Urabe K, Winder A, Jimenez-Cervantes C, Imokawa G, Brewington T, Solano F, Garcia-Borron JC, Hearing VJ (1994) Tyrosinase related protein 1 (trp1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J 13: 5818-5825.
7. Kaufman PB, Duke JA, Brielmann H, Boik J, Hoyt JE (1997) A comparative survey of leguminous plants as sources of the isoflavones, genistein and daidzein: implications for human nutrition and health. J Altern Complement Med 3: 7-12.
8. Xiong FL, Sun XH, Gan L, Yang XL, Xu HB (2006) Puerarin protects rat pancreatic islets from damage by hydrogen peroxide. Eur J Pharmacol 529: 1-7.
9. Lucas EA, Khalil DA, Daggy BP, Arjmandi BH (2001) Ethanol-extracted soy protein isolate does not modulate serum cholesterol in golden Syrian hamsters: a model of postmenopausal hypercholesterolemia. J Nutr 131: 211-214.
10. Lin RC, Li TK (1998) Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats. Am J Clin Nutr 68: 1512S-1515S.
11. Rezvani AH, Overstreet DH, Perfumi M, Massi M (2003) Plant derivatives in the treatment of alcohol dependency. Pharmacol Biochem Behav 75: 593-606.
12. Prasain JK, Jones K, Kirk M, Wilson L, Smith-Johnson M, Weaver C, Barnes S (2003) Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry. J Agric Food Chem 51: 4213-4218.
13. Li D, Park SH, Shim JH, Lee HS, Tang SY, Park CS, Park KH (2004) In vitro enzymatic modification of puerarin to puerarin glycosides by maltogenic amylase. Carb Res 339: 2789-2797.
14. Chung MJ, Sung NJ, Park CS, Kweon DK, Mantovani A, Moon TW, Lee SJ, Park KH (2008) Antioxidative and hypocholesterolemic activities of water-soluble puerarin glycosides in hepg2 cells and in c57 bl/6j mice. Eur J Pharmacol 578: 159-170.
15. Matsuda H, Nakamura S, Kubo M (1994) Studies of cuticle drugs from natural sources. II. Inhibitory effects of Prunus plants on melanin biosynthesis. Biol Pharm Bull 17: 1417-1420.
16. Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121.
17. AMIGO http://amigo. Geneontology. Org.
18. Mouse genome informatics http://www. informatics. jax. org.
19. UniGene database http://www. ncbi. nlm. nih. gov/unigene.
20. Ando H, Kondoh H, Ichihashi M, Hearing VJ (2007) Approaches to identify inhibitors of melanin biosynthesis via the quality control of tyrosinase. J Invest Dermatol 127: 751-761.
21. Schallreuter KU (2007) Advances in melanocyte basic science research. Dermatol Clin 25: 283-291, vii.
22. Solano F, Briganti S, Picardo M, Ghanem G (2006) Hypopigmenting agents: an updated review on biological, chemical and clinical aspects. Pigment Cell Res 19: 550-571.
23. Badria FA, Elgayyar MA (2001) A new type of tyrosinase inhibitors from natural products as potential treatments for hyperpigmentation. Boll Chim Farm 140: 267-271.
24. Shimizu K, Kondo R, Sakai K (2000) Inhibition of tyrosinase by flavonoids, stilbenes and related 4-substituted resorcinols: Structure-activity investigations. Planta Med 66: 11-15.
25. Chang TS (2007) Two potent suicide substrates of mushroom tyrosinase: 7, 8, 4′-trihydroxyisoflavone and 5, 7, 8, 4′-tetrahydroxyisoflavone. J Agric Food Chem 55: 2010-2015.
26. Chang TS, Ding HY, Lin HC (2005) Identifying 6, 7, 4′-trihydroxyisoflavone as a potent tyrosinase inhibitor. Biosci Biotechnol Biochem 69: 1999-2001.
27. Schaffer JV, Bolognia JL (2001) The melanocortin-1 receptor: red hair and beyond. Arch Dermatol 137: 1477-1485.
28. Thody AJ (1999) Alpha-MSH and the regulation of melanocyte function. Ann NY Acad Sci 885: 217-229.
29. Schwyzer R, Eberle A (1977) On the molecular mechanism of alpha-MSH receptor interactions. Front Horm Res 4: 18-25.
30. Goverde HJ, Pesman GJ, Smals AG (1988) The melanotropin potentiating factor and beta-endorphin do not modulate the alpha-melanotropin- or adrenocorticotropin-induced corticosteroidogenesis in purified isolated rat adrenal cells. Neuropeptides 12: 125-130.
31. Huber WE, Price ER, Widlund HR, Du J, Davis IJ, Wegner M, Fisher DE (2003) A tissue-restricted camp transcriptional response: Sox10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes. J Biol Chem 278: 45224-45230.